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PubMed code 23409871

Compile data set for download or QSAR
Found 48 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50380884
PNG
(CHEMBL2018954)
Show SMILES COc1ccc(COc2nc(Br)cnc2NS(=O)(=O)c2ccc(C)cc2)cc1OCCN(C)C
Show InChI InChI=1S/C23H27BrN4O5S/c1-16-5-8-18(9-6-16)34(29,30)27-22-23(26-21(24)14-25-22)33-15-17-7-10-19(31-4)20(13-17)32-12-11-28(2)3/h5-10,13-14H,11-12,15H2,1-4H3,(H,25,27)
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n/an/a 3.90n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50380881
PNG
(CHEMBL2018953)
Show SMILES Clc1ccc(CNc2nc(nc3ncccc23)N2CCN(CC2)C(=O)[C@H]2CCCCN2)c(Cl)c1 |r|
Show InChI InChI=1S/C24H27Cl2N7O/c25-17-7-6-16(19(26)14-17)15-29-22-18-4-3-9-28-21(18)30-24(31-22)33-12-10-32(11-13-33)23(34)20-5-1-2-8-27-20/h3-4,6-7,9,14,20,27H,1-2,5,8,10-13,15H2,(H,28,29,30,31)/t20-/m1/s1
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n/an/a 5.5n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490519
PNG
(CHEMBL2326625)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C4COCCN4C)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C26H28ClN5O5S2/c1-31-11-12-37-16-20(31)26(33)28-14-17-5-3-6-18(13-17)15-32-19-7-4-8-21(36-2)24(19)25(29-32)30-39(34,35)23-10-9-22(27)38-23/h3-10,13,20H,11-12,14-16H2,1-2H3,(H,28,33)(H,29,30)
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n/an/a 6.30n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490515
PNG
(CHEMBL2326611)
Show SMILES CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(CO)cccc23)c1
Show InChI InChI=1S/C22H21ClN4O4S2/c1-14(29)24-11-15-4-2-5-16(10-15)12-27-18-7-3-6-17(13-28)21(18)22(25-27)26-33(30,31)20-9-8-19(23)32-20/h2-10,28H,11-13H2,1H3,(H,24,29)(H,25,26)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490519
PNG
(CHEMBL2326625)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C4COCCN4C)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C26H28ClN5O5S2/c1-31-11-12-37-16-20(31)26(33)28-14-17-5-3-6-18(13-17)15-32-19-7-4-8-21(36-2)24(19)25(29-32)30-39(34,35)23-10-9-22(27)38-23/h3-10,13,20H,11-12,14-16H2,1-2H3,(H,28,33)(H,29,30)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490524
PNG
(CHEMBL2326630)
Show SMILES COc1c(F)ccc2n(Cc3cccc(CNC(C)=O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C22H20ClFN4O4S2/c1-13(29)25-11-14-4-3-5-15(10-14)12-28-17-7-6-16(24)21(32-2)20(17)22(26-28)27-34(30,31)19-9-8-18(23)33-19/h3-10H,11-12H2,1-2H3,(H,25,29)(H,26,27)
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n/an/a 13n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490500
PNG
(CHEMBL2321924)
Show SMILES CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(O)cccc23)c1
Show InChI InChI=1S/C21H19ClN4O4S2/c1-13(27)23-11-14-4-2-5-15(10-14)12-26-16-6-3-7-17(28)20(16)21(24-26)25-32(29,30)19-9-8-18(22)31-19/h2-10,28H,11-12H2,1H3,(H,23,27)(H,24,25)
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n/an/a 13n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490511
PNG
(CHEMBL2326624)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)[C@@H]4COCCN4)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12 |r|
Show InChI InChI=1S/C25H26ClN5O5S2/c1-35-20-7-3-6-19-23(20)24(30-38(33,34)22-9-8-21(26)37-22)29-31(19)14-17-5-2-4-16(12-17)13-28-25(32)18-15-36-11-10-27-18/h2-9,12,18,27H,10-11,13-15H2,1H3,(H,28,32)(H,29,30)/t18-/m0/s1
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490531
PNG
(CHEMBL2326622)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)[C@@H]4CCCCN4)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12 |r|
Show InChI InChI=1S/C26H28ClN5O4S2/c1-36-21-10-5-9-20-24(21)25(31-38(34,35)23-12-11-22(27)37-23)30-32(20)16-18-7-4-6-17(14-18)15-29-26(33)19-8-2-3-13-28-19/h4-7,9-12,14,19,28H,2-3,8,13,15-16H2,1H3,(H,29,33)(H,30,31)/t19-/m0/s1
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490530
PNG
(CHEMBL2326926)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(C)c(F)c3)c12
Show InChI InChI=1S/C27H29FN4O5S/c1-17-11-12-20(14-21(17)28)38(35,36)31-25-24-22(9-6-10-23(24)37-4)32(30-25)16-19-8-5-7-18(13-19)15-29-26(33)27(2,3)34/h5-14,34H,15-16H2,1-4H3,(H,29,33)(H,30,31)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490512
PNG
(CHEMBL2326621)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)N)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H26ClN5O4S2/c1-24(2,26)23(31)27-13-15-6-4-7-16(12-15)14-30-17-8-5-9-18(34-3)21(17)22(28-30)29-36(32,33)20-11-10-19(25)35-20/h4-12H,13-14,26H2,1-3H3,(H,27,31)(H,28,29)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490506
PNG
(CHEMBL2326633)
Show SMILES COc1cc(F)cc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H24ClFN4O5S2/c1-24(2,32)23(31)27-12-14-5-4-6-15(9-14)13-30-17-10-16(26)11-18(35-3)21(17)22(28-30)29-37(33,34)20-8-7-19(25)36-20/h4-11,32H,12-13H2,1-3H3,(H,27,31)(H,28,29)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490520
PNG
(CHEMBL2326620)
Show SMILES CN[C@H](C)C(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(OC)cccc23)c1 |r|
Show InChI InChI=1S/C24H26ClN5O4S2/c1-15(26-2)24(31)27-13-16-6-4-7-17(12-16)14-30-18-8-5-9-19(34-3)22(18)23(28-30)29-36(32,33)21-11-10-20(25)35-21/h4-12,15,26H,13-14H2,1-3H3,(H,27,31)(H,28,29)/t15-/m1/s1
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490522
PNG
(CHEMBL2326616)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C4COC4)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H23ClN4O5S2/c1-33-19-7-3-6-18-22(19)23(28-36(31,32)21-9-8-20(25)35-21)27-29(18)12-16-5-2-4-15(10-16)11-26-24(30)17-13-34-14-17/h2-10,17H,11-14H2,1H3,(H,26,30)(H,27,28)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490518
PNG
(CHEMBL2326613)
Show SMILES CC(O)c1cccc2n(Cc3cccc(CNC(C)=O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C23H23ClN4O4S2/c1-14(29)18-7-4-8-19-22(18)23(27-34(31,32)21-10-9-20(24)33-21)26-28(19)13-17-6-3-5-16(11-17)12-25-15(2)30/h3-11,14,29H,12-13H2,1-2H3,(H,25,30)(H,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490517
PNG
(CHEMBL2326623)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)[C@H]4COCCN4)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12 |r|
Show InChI InChI=1S/C25H26ClN5O5S2/c1-35-20-7-3-6-19-23(20)24(30-38(33,34)22-9-8-21(26)37-22)29-31(19)14-17-5-2-4-16(12-17)13-28-25(32)18-15-36-11-10-27-18/h2-9,12,18,27H,10-11,13-15H2,1H3,(H,28,32)(H,29,30)/t18-/m1/s1
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50380867
PNG
(CHEMBL2018964)
Show SMILES COc1cccc2n(Cc3cccc(CNC(C)=O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C22H21ClN4O4S2/c1-14(28)24-12-15-5-3-6-16(11-15)13-27-17-7-4-8-18(31-2)21(17)22(25-27)26-33(29,30)20-10-9-19(23)32-20/h3-11H,12-13H2,1-2H3,(H,24,28)(H,25,26)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490529
PNG
(CHEMBL2326617)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C4CCO4)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H23ClN4O5S2/c1-33-18-7-3-6-17-22(18)23(28-36(31,32)21-9-8-20(25)35-21)27-29(17)14-16-5-2-4-15(12-16)13-26-24(30)19-10-11-34-19/h2-9,12,19H,10-11,13-14H2,1H3,(H,26,30)(H,27,28)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490525
PNG
(CHEMBL2326619)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C4CCOCC4)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C26H27ClN4O5S2/c1-35-21-7-3-6-20-24(21)25(30-38(33,34)23-9-8-22(27)37-23)29-31(20)16-18-5-2-4-17(14-18)15-28-26(32)19-10-12-36-13-11-19/h2-9,14,19H,10-13,15-16H2,1H3,(H,28,32)(H,29,30)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490502
PNG
(CHEMBL2326608)
Show SMILES CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(Cl)cccc23)c1
Show InChI InChI=1S/C21H18Cl2N4O3S2/c1-13(28)24-11-14-4-2-5-15(10-14)12-27-17-7-3-6-16(22)20(17)21(25-27)26-32(29,30)19-9-8-18(23)31-19/h2-10H,11-12H2,1H3,(H,24,28)(H,25,26)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50380880
PNG
(CHEMBL2018969)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490516
PNG
(CHEMBL2326632)
Show SMILES COc1cc(F)cc2n(Cc3cccc(CNC(C)=O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C22H20ClFN4O4S2/c1-13(29)25-11-14-4-3-5-15(8-14)12-28-17-9-16(24)10-18(32-2)21(17)22(26-28)27-34(30,31)20-7-6-19(23)33-20/h3-10H,11-12H2,1-2H3,(H,25,29)(H,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490513
PNG
(CHEMBL2326618)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C4CCCO4)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C25H25ClN4O5S2/c1-34-19-8-3-7-18-23(19)24(29-37(32,33)22-11-10-21(26)36-22)28-30(18)15-17-6-2-5-16(13-17)14-27-25(31)20-9-4-12-35-20/h2-3,5-8,10-11,13,20H,4,9,12,14-15H2,1H3,(H,27,31)(H,28,29)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490507
PNG
(CHEMBL2326631)
Show SMILES COc1c(F)ccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H24ClFN4O5S2/c1-24(2,32)23(31)27-12-14-5-4-6-15(11-14)13-30-17-8-7-16(26)21(35-3)20(17)22(28-30)29-37(33,34)19-10-9-18(25)36-19/h4-11,32H,12-13H2,1-3H3,(H,27,31)(H,28,29)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490504
PNG
(CHEMBL2326924)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3cccc(Cl)c3)c12
Show InChI InChI=1S/C26H27ClN4O5S/c1-26(2,33)25(32)28-15-17-7-4-8-18(13-17)16-31-21-11-6-12-22(36-3)23(21)24(29-31)30-37(34,35)20-10-5-9-19(27)14-20/h4-14,33H,15-16H2,1-3H3,(H,28,32)(H,29,30)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490532
PNG
(CHEMBL2326609)
Show SMILES CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(F)cccc23)c1
Show InChI InChI=1S/C21H18ClFN4O3S2/c1-13(28)24-11-14-4-2-5-15(10-14)12-27-17-7-3-6-16(23)20(17)21(25-27)26-32(29,30)19-9-8-18(22)31-19/h2-10H,11-12H2,1H3,(H,24,28)(H,25,26)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490505
PNG
(CHEMBL2326634)
Show SMILES COc1ccc(F)c2n(Cc3cccc(CNC(C)=O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C22H20ClFN4O4S2/c1-13(29)25-11-14-4-3-5-15(10-14)12-28-21-16(24)6-7-17(32-2)20(21)22(26-28)27-34(30,31)19-9-8-18(23)33-19/h3-10H,11-12H2,1-2H3,(H,25,29)(H,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490521
PNG
(CHEMBL2326615)
Show SMILES CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(cccc23)C(F)F)c1
Show InChI InChI=1S/C22H19ClF2N4O3S2/c1-13(30)26-11-14-4-2-5-15(10-14)12-29-17-7-3-6-16(21(24)25)20(17)22(27-29)28-34(31,32)19-9-8-18(23)33-19/h2-10,21H,11-12H2,1H3,(H,26,30)(H,27,28)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490526
PNG
(CHEMBL2326614)
Show SMILES CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(cccc23)C(C)(C)O)c1
Show InChI InChI=1S/C24H25ClN4O4S2/c1-15(30)26-13-16-6-4-7-17(12-16)14-29-19-9-5-8-18(24(2,3)31)22(19)23(27-29)28-35(32,33)21-11-10-20(25)34-21/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490514
PNG
(CHEMBL2326612)
Show SMILES CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(cccc23)C(C)=O)c1
Show InChI InChI=1S/C23H21ClN4O4S2/c1-14(29)18-7-4-8-19-22(18)23(27-34(31,32)21-10-9-20(24)33-21)26-28(19)13-17-6-3-5-16(11-17)12-25-15(2)30/h3-11H,12-13H2,1-2H3,(H,25,30)(H,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490528
PNG
(CHEMBL2326628)
Show SMILES COc1cccc2n(Cc3ccnc(CNC(C)=O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C21H20ClN5O4S2/c1-13(28)24-11-15-10-14(8-9-23-15)12-27-16-4-3-5-17(31-2)20(16)21(25-27)26-33(29,30)19-7-6-18(22)32-19/h3-10H,11-12H2,1-2H3,(H,24,28)(H,25,26)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490508
PNG
(CHEMBL2326629)
Show SMILES COc1cccc2n(Cc3cccc(CNC(C)=O)n3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C21H20ClN5O4S2/c1-13(28)23-11-14-5-3-6-15(24-14)12-27-16-7-4-8-17(31-2)20(16)21(25-27)26-33(29,30)19-10-9-18(22)32-19/h3-10H,11-12H2,1-2H3,(H,23,28)(H,25,26)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490509
PNG
(CHEMBL2326627)
Show SMILES COc1cccc2n(Cc3cc(CNC(C)=O)ccn3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C21H20ClN5O4S2/c1-13(28)24-11-14-8-9-23-15(10-14)12-27-16-4-3-5-17(31-2)20(16)21(25-27)26-33(29,30)19-7-6-18(22)32-19/h3-10H,11-12H2,1-2H3,(H,24,28)(H,25,26)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490527
PNG
(CHEMBL2326927)
Show SMILES CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3ccccc23)c1
Show InChI InChI=1S/C21H19ClN4O3S2/c1-14(27)23-12-15-5-4-6-16(11-15)13-26-18-8-3-2-7-17(18)21(24-26)25-31(28,29)20-10-9-19(22)30-20/h2-11H,12-13H2,1H3,(H,23,27)(H,24,25)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490510
PNG
(CHEMBL2326626)
Show SMILES COc1cccc2n(Cc3cccc(CNC4COC4)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C23H23ClN4O4S2/c1-31-19-7-3-6-18-22(19)23(27-34(29,30)21-9-8-20(24)33-21)26-28(18)12-16-5-2-4-15(10-16)11-25-17-13-32-14-17/h2-10,17,25H,11-14H2,1H3,(H,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490501
PNG
(CHEMBL2326610)
Show SMILES CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(cccc23)C#N)c1
Show InChI InChI=1S/C22H18ClN5O3S2/c1-14(29)25-12-15-4-2-5-16(10-15)13-28-18-7-3-6-17(11-24)21(18)22(26-28)27-33(30,31)20-9-8-19(23)32-20/h2-10H,12-13H2,1H3,(H,25,29)(H,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490523
PNG
(CHEMBL2326923)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)c(Cl)c3)c12
Show InChI InChI=1S/C26H26Cl2N4O5S/c1-26(2,34)25(33)29-14-16-6-4-7-17(12-16)15-32-21-8-5-9-22(37-3)23(21)24(30-32)31-38(35,36)18-10-11-19(27)20(28)13-18/h4-13,34H,14-15H2,1-3H3,(H,29,33)(H,30,31)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
Solute carrier organic anion transporter family member 1B1


(Homo sapiens (Human))		BDBM50380880
PNG
(CHEMBL2018969)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)
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n/an/a 398n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at OATP1B1 (unknown origin) by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50490503
PNG
(CHEMBL2326925)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3cccc(Cl)c3Cl)c12
Show InChI InChI=1S/C26H26Cl2N4O5S/c1-26(2,34)25(33)29-14-16-7-4-8-17(13-16)15-32-19-10-6-11-20(37-3)22(19)24(30-32)31-38(35,36)21-12-5-9-18(27)23(21)28/h4-13,34H,14-15H2,1-3H3,(H,29,33)(H,30,31)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50380880
PNG
(CHEMBL2018969)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)
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n/an/a 6.31E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CCR5 receptor (unknown origin) by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 8


(Homo sapiens (Human))		BDBM50380880
PNG
(CHEMBL2018969)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)
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n/an/a<1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CCR8 receptor (unknown origin) by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 10


(Homo sapiens (Human))		BDBM50380880
PNG
(CHEMBL2018969)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)
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n/an/a<1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CCR10 receptor (unknown origin) by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-X-C chemokine receptor type 1


(Homo sapiens (Human))		BDBM50380880
PNG
(CHEMBL2018969)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)
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n/an/a<1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CXCR1 receptor (unknown origin) by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-X-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50380880
PNG
(CHEMBL2018969)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)
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n/an/a<1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CXCR4 receptor (unknown origin) by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 1


(Homo sapiens (Human))		BDBM50380880
PNG
(CHEMBL2018969)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)
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n/an/a<1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CCR1 receptor (unknown origin) by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50380880
PNG
(CHEMBL2018969)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)
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n/an/a<1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CCR2 receptor (unknown origin) by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50380880
PNG
(CHEMBL2018969)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)
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n/an/a<1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CXCR2 receptor (unknown origin) by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
C-X-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50380880
PNG
(CHEMBL2018969)
Show SMILES COc1cccc2n(Cc3cccc(CNC(=O)C(C)(C)O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12
Show InChI InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)
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n/an/a<1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CXCR3 receptor (unknown origin) by [35S]GTPgammaS binding assay

J Med Chem 56: 1946-60 (2013)


Article DOI: 10.1021/jm301572h
BindingDB Entry DOI: 10.7270/Q26W9F07
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%