Affinity Data by PubMed id=23528299

PubMed code 23528299

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aminopeptidase N (Sus scrofa (Pig))	BDBM50435266 (CHEMBL2393088) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of pig kidney APN using L-Leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by UV-Vi...				Bioorg Med Chem Lett 23: 2512-7 (2013) Article DOI: 10.1016/j.bmcl.2013.03.021 BindingDB Entry DOI: 10.7270/Q21G0NN4
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50435266 (CHEMBL2393088) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of APN in human ES-2 cells using L-Leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured after 1 hr by...				Bioorg Med Chem Lett 23: 2512-7 (2013) Article DOI: 10.1016/j.bmcl.2013.03.021 BindingDB Entry DOI: 10.7270/Q21G0NN4
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of pig kidney APN using L-Leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by UV-Vi...				Bioorg Med Chem Lett 23: 2512-7 (2013) Article DOI: 10.1016/j.bmcl.2013.03.021 BindingDB Entry DOI: 10.7270/Q21G0NN4
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Aminopeptidase N (Homo sapiens (Human))	BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of APN in human ES-2 cells using L-Leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured after 1 hr by...				Bioorg Med Chem Lett 23: 2512-7 (2013) Article DOI: 10.1016/j.bmcl.2013.03.021 BindingDB Entry DOI: 10.7270/Q21G0NN4
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%