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PubMed code 23712084

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50436356
PNG
(CHEMBL2396702)
Show SMILES FCCCCCNC(=O)Oc1cccc(c1)C1=NCCO1 |t:17|
Show InChI InChI=1S/C15H19FN2O3/c16-7-2-1-3-8-18-15(19)21-13-6-4-5-12(11-13)14-17-9-10-20-14/h4-6,11H,1-3,7-10H2,(H,18,19)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.813n/an/an/an/an/an/a



Centre for Addiction and Mental Health

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain homogenates using [3H]anandamide as substrate preincubated for 60 mins by liquid scintillation spectroscopy


Bioorg Med Chem 21: 4351-7 (2013)


Article DOI: 10.1016/j.bmc.2013.04.077
BindingDB Entry DOI: 10.7270/Q2RN398F
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50436356
PNG
(CHEMBL2396702)
Show SMILES FCCCCCNC(=O)Oc1cccc(c1)C1=NCCO1 |t:17|
Show InChI InChI=1S/C15H19FN2O3/c16-7-2-1-3-8-18-15(19)21-13-6-4-5-12(11-13)14-17-9-10-20-14/h4-6,11H,1-3,7-10H2,(H,18,19)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.820n/an/an/an/an/an/a



Centre for Addiction and Mental Health

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain homogenates using [3H]anandamide as substrate preincubated for 60 mins by liquid scintillation spectroscopy


Bioorg Med Chem 21: 4351-7 (2013)


Article DOI: 10.1016/j.bmc.2013.04.077
BindingDB Entry DOI: 10.7270/Q2RN398F
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%