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PubMed code 24083878

Compile data set for download or QSAR
Found 61 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442954
PNG
(CHEMBL3087192)
Show SMILES COc1nn([C@@H](C)c2ccc(CC(C)C)cc2)c(=O)o1 |r|
Show InChI InChI=1S/C15H20N2O3/c1-10(2)9-12-5-7-13(8-6-12)11(3)17-15(18)20-14(16-17)19-4/h5-8,10-11H,9H2,1-4H3/t11-/m0/s1
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n/an/a 11n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50442946
PNG
(CHEMBL3087191)
Show SMILES COc1nn(C(C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1
Show InChI InChI=1S/C23H21N3O3/c1-17(26-23(27)29-22(24-26)28-2)18-13-15-21(16-14-18)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-17H,1-2H3
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n/an/a 11n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat RBL2H3 cells assessed as blockade of [3H]-anandamide uptake incubated for 15 mins prior to [3H]-anandamide addition measure...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442954
PNG
(CHEMBL3087192)
Show SMILES COc1nn([C@@H](C)c2ccc(CC(C)C)cc2)c(=O)o1 |r|
Show InChI InChI=1S/C15H20N2O3/c1-10(2)9-12-5-7-13(8-6-12)11(3)17-15(18)20-14(16-17)19-4/h5-8,10-11H,9H2,1-4H3/t11-/m0/s1
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University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50350547
PNG
(CHEMBL257307)
Show SMILES CCCCCCCCCCCC(=O)c1nc2ncccc2o1
Show InChI InChI=1S/C18H26N2O2/c1-2-3-4-5-6-7-8-9-10-12-15(21)18-20-17-16(22-18)13-11-14-19-17/h11,13-14H,2-10,12H2,1H3
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n/an/a 17n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50350547
PNG
(CHEMBL257307)
Show SMILES CCCCCCCCCCCC(=O)c1nc2ncccc2o1
Show InChI InChI=1S/C18H26N2O2/c1-2-3-4-5-6-7-8-9-10-12-15(21)18-20-17-16(22-18)13-11-14-19-17/h11,13-14H,2-10,12H2,1H3
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n/an/a 17n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442953
PNG
(CHEMBL3087168)
Show SMILES COc1nn([C@@H](C)c2ccc(cc2)-c2ccccc2)c(=O)o1 |r|
Show InChI InChI=1S/C17H16N2O3/c1-12(19-17(20)22-16(18-19)21-2)13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-12H,1-2H3/t12-/m0/s1
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n/an/a 23n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442959
PNG
(CHEMBL3087182)
Show SMILES COc1nn(C(C)c2ccc(CC(C)C)cc2)c(=O)o1
Show InChI InChI=1S/C15H20N2O3/c1-10(2)9-12-5-7-13(8-6-12)11(3)17-15(18)20-14(16-17)19-4/h5-8,10-11H,9H2,1-4H3
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n/an/a 23n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442959
PNG
(CHEMBL3087182)
Show SMILES COc1nn(C(C)c2ccc(CC(C)C)cc2)c(=O)o1
Show InChI InChI=1S/C15H20N2O3/c1-10(2)9-12-5-7-13(8-6-12)11(3)17-15(18)20-14(16-17)19-4/h5-8,10-11H,9H2,1-4H3
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n/an/a 23n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442953
PNG
(CHEMBL3087168)
Show SMILES COc1nn([C@@H](C)c2ccc(cc2)-c2ccccc2)c(=O)o1 |r|
Show InChI InChI=1S/C17H16N2O3/c1-12(19-17(20)22-16(18-19)21-2)13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-12H,1-2H3/t12-/m0/s1
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n/an/a 23n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442947
PNG
(CHEMBL3087185)
Show SMILES COc1nn(C(C)c2ccc(Oc3ccccc3)cc2)c(=O)o1
Show InChI InChI=1S/C17H16N2O4/c1-12(19-17(20)23-16(18-19)21-2)13-8-10-15(11-9-13)22-14-6-4-3-5-7-14/h3-12H,1-2H3
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n/an/a 34n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442947
PNG
(CHEMBL3087185)
Show SMILES COc1nn(C(C)c2ccc(Oc3ccccc3)cc2)c(=O)o1
Show InChI InChI=1S/C17H16N2O4/c1-12(19-17(20)23-16(18-19)21-2)13-8-10-15(11-9-13)22-14-6-4-3-5-7-14/h3-12H,1-2H3
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n/an/a 34n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442958
PNG
(CHEMBL3087183)
Show SMILES COc1nn(C(C)c2ccc(cc2)-c2ccccc2)c(=O)o1
Show InChI InChI=1S/C17H16N2O3/c1-12(19-17(20)22-16(18-19)21-2)13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-12H,1-2H3
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n/an/a 47n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442958
PNG
(CHEMBL3087183)
Show SMILES COc1nn(C(C)c2ccc(cc2)-c2ccccc2)c(=O)o1
Show InChI InChI=1S/C17H16N2O3/c1-12(19-17(20)22-16(18-19)21-2)13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-12H,1-2H3
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University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442943
PNG
(CHEMBL3087173)
Show SMILES COc1nn(Cc2ccc(CC(C)C)cc2)c(=O)o1
Show InChI InChI=1S/C14H18N2O3/c1-10(2)8-11-4-6-12(7-5-11)9-16-14(17)19-13(15-16)18-3/h4-7,10H,8-9H2,1-3H3
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n/an/a 89n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442943
PNG
(CHEMBL3087173)
Show SMILES COc1nn(Cc2ccc(CC(C)C)cc2)c(=O)o1
Show InChI InChI=1S/C14H18N2O3/c1-10(2)8-11-4-6-12(7-5-11)9-16-14(17)19-13(15-16)18-3/h4-7,10H,8-9H2,1-3H3
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University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442951
PNG
(CHEMBL3087170)
Show SMILES COc1nn([C@@H](C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1 |r|
Show InChI InChI=1S/C23H21N3O3/c1-17(26-23(27)29-22(24-26)28-2)18-13-15-21(16-14-18)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-17H,1-2H3/t17-/m0/s1
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University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442951
PNG
(CHEMBL3087170)
Show SMILES COc1nn([C@@H](C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1 |r|
Show InChI InChI=1S/C23H21N3O3/c1-17(26-23(27)29-22(24-26)28-2)18-13-15-21(16-14-18)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-17H,1-2H3/t17-/m0/s1
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University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442941
PNG
(CHEMBL3087178)
Show SMILES COc1nn(Cc2ccc(Oc3ccccc3)cc2)c(=O)o1
Show InChI InChI=1S/C16H14N2O4/c1-20-15-17-18(16(19)22-15)11-12-7-9-14(10-8-12)21-13-5-3-2-4-6-13/h2-10H,11H2,1H3
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University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442941
PNG
(CHEMBL3087178)
Show SMILES COc1nn(Cc2ccc(Oc3ccccc3)cc2)c(=O)o1
Show InChI InChI=1S/C16H14N2O4/c1-20-15-17-18(16(19)22-15)11-12-7-9-14(10-8-12)21-13-5-3-2-4-6-13/h2-10H,11H2,1H3
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University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442946
PNG
(CHEMBL3087191)
Show SMILES COc1nn(C(C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1
Show InChI InChI=1S/C23H21N3O3/c1-17(26-23(27)29-22(24-26)28-2)18-13-15-21(16-14-18)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-17H,1-2H3
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University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442946
PNG
(CHEMBL3087191)
Show SMILES COc1nn(C(C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1
Show InChI InChI=1S/C23H21N3O3/c1-17(26-23(27)29-22(24-26)28-2)18-13-15-21(16-14-18)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-17H,1-2H3
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University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442942
PNG
(CHEMBL3087174)
Show SMILES COc1nn(Cc2ccc(cc2)-c2ccccc2)c(=O)o1
Show InChI InChI=1S/C16H14N2O3/c1-20-15-17-18(16(19)21-15)11-12-7-9-14(10-8-12)13-5-3-2-4-6-13/h2-10H,11H2,1H3
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n/an/a 160n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442942
PNG
(CHEMBL3087174)
Show SMILES COc1nn(Cc2ccc(cc2)-c2ccccc2)c(=O)o1
Show InChI InChI=1S/C16H14N2O3/c1-20-15-17-18(16(19)21-15)11-12-7-9-14(10-8-12)13-5-3-2-4-6-13/h2-10H,11H2,1H3
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n/an/a 162n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM26739
PNG
(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
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n/an/a 166n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM26739
PNG
(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
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n/an/a 170n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442945
PNG
(CHEMBL3087314)
Show SMILES COc1nn([C@H](C)c2ccc(CC(C)C)cc2)c(=O)o1 |r|
Show InChI InChI=1S/C15H20N2O3/c1-10(2)9-12-5-7-13(8-6-12)11(3)17-15(18)20-14(16-17)19-4/h5-8,10-11H,9H2,1-4H3/t11-/m1/s1
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n/an/a 240n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442945
PNG
(CHEMBL3087314)
Show SMILES COc1nn([C@H](C)c2ccc(CC(C)C)cc2)c(=O)o1 |r|
Show InChI InChI=1S/C15H20N2O3/c1-10(2)9-12-5-7-13(8-6-12)11(3)17-15(18)20-14(16-17)19-4/h5-8,10-11H,9H2,1-4H3/t11-/m1/s1
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n/an/a 245n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442940
PNG
(CHEMBL3087179)
Show SMILES COc1nn(Cc2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1
Show InChI InChI=1S/C22H19N3O3/c1-27-21-23-24(22(26)28-21)16-17-12-14-20(15-13-17)25(18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-15H,16H2,1H3
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n/an/a 251n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442940
PNG
(CHEMBL3087179)
Show SMILES COc1nn(Cc2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1
Show InChI InChI=1S/C22H19N3O3/c1-27-21-23-24(22(26)28-21)16-17-12-14-20(15-13-17)25(18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-15H,16H2,1H3
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n/an/a 260n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442948
PNG
(CHEMBL3087180)
Show SMILES O=C(Nc1ccccc1)N1CCC(Cc2ccc3ccccc3n2)CC1
Show InChI InChI=1S/C22H23N3O/c26-22(24-19-7-2-1-3-8-19)25-14-12-17(13-15-25)16-20-11-10-18-6-4-5-9-21(18)23-20/h1-11,17H,12-16H2,(H,24,26)
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n/an/a 320n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442948
PNG
(CHEMBL3087180)
Show SMILES O=C(Nc1ccccc1)N1CCC(Cc2ccc3ccccc3n2)CC1
Show InChI InChI=1S/C22H23N3O/c26-22(24-19-7-2-1-3-8-19)25-14-12-17(13-15-25)16-20-11-10-18-6-4-5-9-21(18)23-20/h1-11,17H,12-16H2,(H,24,26)
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n/an/a 324n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442944
PNG
(CHEMBL3087171)
Show SMILES COc1nn([C@H](C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1 |r|
Show InChI InChI=1S/C23H21N3O3/c1-17(26-23(27)29-22(24-26)28-2)18-13-15-21(16-14-18)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-17H,1-2H3/t17-/m1/s1
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n/an/a 339n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442944
PNG
(CHEMBL3087171)
Show SMILES COc1nn([C@H](C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1 |r|
Show InChI InChI=1S/C23H21N3O3/c1-17(26-23(27)29-22(24-26)28-2)18-13-15-21(16-14-18)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-17H,1-2H3/t17-/m1/s1
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n/an/a 350n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442941
PNG
(CHEMBL3087178)
Show SMILES COc1nn(Cc2ccc(Oc3ccccc3)cc2)c(=O)o1
Show InChI InChI=1S/C16H14N2O4/c1-20-15-17-18(16(19)22-15)11-12-7-9-14(10-8-12)21-13-5-3-2-4-6-13/h2-10H,11H2,1H3
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n/an/a 398n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442941
PNG
(CHEMBL3087178)
Show SMILES COc1nn(Cc2ccc(Oc3ccccc3)cc2)c(=O)o1
Show InChI InChI=1S/C16H14N2O4/c1-20-15-17-18(16(19)22-15)11-12-7-9-14(10-8-12)21-13-5-3-2-4-6-13/h2-10H,11H2,1H3
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n/an/a 400n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442940
PNG
(CHEMBL3087179)
Show SMILES COc1nn(Cc2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1
Show InChI InChI=1S/C22H19N3O3/c1-27-21-23-24(22(26)28-21)16-17-12-14-20(15-13-17)25(18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-15H,16H2,1H3
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n/an/a 457n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442940
PNG
(CHEMBL3087179)
Show SMILES COc1nn(Cc2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1
Show InChI InChI=1S/C22H19N3O3/c1-27-21-23-24(22(26)28-21)16-17-12-14-20(15-13-17)25(18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-15H,16H2,1H3
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n/an/a 470n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442946
PNG
(CHEMBL3087191)
Show SMILES COc1nn(C(C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1
Show InChI InChI=1S/C23H21N3O3/c1-17(26-23(27)29-22(24-26)28-2)18-13-15-21(16-14-18)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-17H,1-2H3
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n/an/a 630n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442946
PNG
(CHEMBL3087191)
Show SMILES COc1nn(C(C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1
Show InChI InChI=1S/C23H21N3O3/c1-17(26-23(27)29-22(24-26)28-2)18-13-15-21(16-14-18)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-17H,1-2H3
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n/an/a 631n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442949
PNG
(CHEMBL3087177)
Show SMILES COc1nn(Cc2cccc(Oc3ccccc3)c2)c(=O)o1
Show InChI InChI=1S/C16H14N2O4/c1-20-15-17-18(16(19)22-15)11-12-6-5-9-14(10-12)21-13-7-3-2-4-8-13/h2-10H,11H2,1H3
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n/an/a 977n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442949
PNG
(CHEMBL3087177)
Show SMILES COc1nn(Cc2cccc(Oc3ccccc3)c2)c(=O)o1
Show InChI InChI=1S/C16H14N2O4/c1-20-15-17-18(16(19)22-15)11-12-6-5-9-14(10-12)21-13-7-3-2-4-8-13/h2-10H,11H2,1H3
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n/an/a 980n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442957
PNG
(CHEMBL3087184)
Show SMILES COc1nn(C(C)c2cccc(c2)-c2ccccc2)c(=O)o1
Show InChI InChI=1S/C17H16N2O3/c1-12(19-17(20)22-16(18-19)21-2)14-9-6-10-15(11-14)13-7-4-3-5-8-13/h3-12H,1-2H3
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n/an/a 1.18E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442957
PNG
(CHEMBL3087184)
Show SMILES COc1nn(C(C)c2cccc(c2)-c2ccccc2)c(=O)o1
Show InChI InChI=1S/C17H16N2O3/c1-12(19-17(20)22-16(18-19)21-2)14-9-6-10-15(11-14)13-7-4-3-5-8-13/h3-12H,1-2H3
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n/an/a 1.20E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442943
PNG
(CHEMBL3087173)
Show SMILES COc1nn(Cc2ccc(CC(C)C)cc2)c(=O)o1
Show InChI InChI=1S/C14H18N2O3/c1-10(2)8-11-4-6-12(7-5-11)9-16-14(17)19-13(15-16)18-3/h4-7,10H,8-9H2,1-3H3
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n/an/a 1.30E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442943
PNG
(CHEMBL3087173)
Show SMILES COc1nn(Cc2ccc(CC(C)C)cc2)c(=O)o1
Show InChI InChI=1S/C14H18N2O3/c1-10(2)8-11-4-6-12(7-5-11)9-16-14(17)19-13(15-16)18-3/h4-7,10H,8-9H2,1-3H3
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n/an/a 1.35E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442942
PNG
(CHEMBL3087174)
Show SMILES COc1nn(Cc2ccc(cc2)-c2ccccc2)c(=O)o1
Show InChI InChI=1S/C16H14N2O3/c1-20-15-17-18(16(19)21-15)11-12-7-9-14(10-8-12)13-5-3-2-4-6-13/h2-10H,11H2,1H3
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n/an/a 1.60E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442942
PNG
(CHEMBL3087174)
Show SMILES COc1nn(Cc2ccc(cc2)-c2ccccc2)c(=O)o1
Show InChI InChI=1S/C16H14N2O3/c1-20-15-17-18(16(19)21-15)11-12-7-9-14(10-8-12)13-5-3-2-4-6-13/h2-10H,11H2,1H3
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n/an/a 1.62E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442947
PNG
(CHEMBL3087185)
Show SMILES COc1nn(C(C)c2ccc(Oc3ccccc3)cc2)c(=O)o1
Show InChI InChI=1S/C17H16N2O4/c1-12(19-17(20)23-16(18-19)21-2)13-8-10-15(11-9-13)22-14-6-4-3-5-7-14/h3-12H,1-2H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442947
PNG
(CHEMBL3087185)
Show SMILES COc1nn(C(C)c2ccc(Oc3ccccc3)cc2)c(=O)o1
Show InChI InChI=1S/C17H16N2O4/c1-12(19-17(20)23-16(18-19)21-2)13-8-10-15(11-9-13)22-14-6-4-3-5-7-14/h3-12H,1-2H3
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n/an/a 2.09E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442952
PNG
(CHEMBL3087169)
Show SMILES COc1nn([C@H](C)c2ccc(cc2)-c2ccccc2)c(=O)o1 |r|
Show InChI InChI=1S/C17H16N2O3/c1-12(19-17(20)22-16(18-19)21-2)13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-12H,1-2H3/t12-/m1/s1
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n/an/a 2.88E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442952
PNG
(CHEMBL3087169)
Show SMILES COc1nn([C@H](C)c2ccc(cc2)-c2ccccc2)c(=O)o1 |r|
Show InChI InChI=1S/C17H16N2O3/c1-12(19-17(20)22-16(18-19)21-2)13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-12H,1-2H3/t12-/m1/s1
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n/an/a 3.00E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442956
PNG
(CHEMBL3087186)
Show SMILES COc1nn(C(C)c2cccc(Oc3ccccc3)c2)c(=O)o1
Show InChI InChI=1S/C17H16N2O4/c1-12(19-17(20)23-16(18-19)21-2)13-7-6-10-15(11-13)22-14-8-4-3-5-9-14/h3-12H,1-2H3
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n/an/a 5.20E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442956
PNG
(CHEMBL3087186)
Show SMILES COc1nn(C(C)c2cccc(Oc3ccccc3)c2)c(=O)o1
Show InChI InChI=1S/C17H16N2O4/c1-12(19-17(20)23-16(18-19)21-2)13-7-6-10-15(11-13)22-14-8-4-3-5-9-14/h3-12H,1-2H3
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n/an/a 5.25E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442955
PNG
(CHEMBL3087189)
Show SMILES COc1nn(C(C)c2ccccc2)c(=O)o1
Show InChI InChI=1S/C11H12N2O3/c1-8(9-6-4-3-5-7-9)13-11(14)16-10(12-13)15-2/h3-8H,1-2H3
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n/an/a 6.00E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442955
PNG
(CHEMBL3087189)
Show SMILES COc1nn(C(C)c2ccccc2)c(=O)o1
Show InChI InChI=1S/C11H12N2O3/c1-8(9-6-4-3-5-7-9)13-11(14)16-10(12-13)15-2/h3-8H,1-2H3
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n/an/a 6.03E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442944
PNG
(CHEMBL3087171)
Show SMILES COc1nn([C@H](C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1 |r|
Show InChI InChI=1S/C23H21N3O3/c1-17(26-23(27)29-22(24-26)28-2)18-13-15-21(16-14-18)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-17H,1-2H3/t17-/m1/s1
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n/an/a 6.17E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442944
PNG
(CHEMBL3087171)
Show SMILES COc1nn([C@H](C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1 |r|
Show InChI InChI=1S/C23H21N3O3/c1-17(26-23(27)29-22(24-26)28-2)18-13-15-21(16-14-18)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-17H,1-2H3/t17-/m1/s1
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n/an/a 6.30E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442950
PNG
(CHEMBL3087176)
Show SMILES COc1nn(Cc2ccccc2Oc2ccccc2)c(=O)o1
Show InChI InChI=1S/C16H14N2O4/c1-20-15-17-18(16(19)22-15)11-12-7-5-6-10-14(12)21-13-8-3-2-4-9-13/h2-10H,11H2,1H3
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n/an/a 6.30E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50442950
PNG
(CHEMBL3087176)
Show SMILES COc1nn(Cc2ccccc2Oc2ccccc2)c(=O)o1
Show InChI InChI=1S/C16H14N2O4/c1-20-15-17-18(16(19)22-15)11-12-7-5-6-10-14(12)21-13-8-3-2-4-9-13/h2-10H,11H2,1H3
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n/an/a 6.31E+3n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442945
PNG
(CHEMBL3087314)
Show SMILES COc1nn([C@H](C)c2ccc(CC(C)C)cc2)c(=O)o1 |r|
Show InChI InChI=1S/C15H20N2O3/c1-10(2)9-12-5-7-13(8-6-12)11(3)17-15(18)20-14(16-17)19-4/h5-8,10-11H,9H2,1-4H3/t11-/m1/s1
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n/an/a 1.34E+4n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))		BDBM50442945
PNG
(CHEMBL3087314)
Show SMILES COc1nn([C@H](C)c2ccc(CC(C)C)cc2)c(=O)o1 |r|
Show InChI InChI=1S/C15H20N2O3/c1-10(2)9-12-5-7-13(8-6-12)11(3)17-15(18)20-14(16-17)19-4/h5-8,10-11H,9H2,1-4H3/t11-/m1/s1
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n/an/a 1.35E+4n/an/an/an/an/an/a



University of Eastern Finland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...

J Med Chem 56: 8484-96 (2013)


Article DOI: 10.1021/jm400923s
BindingDB Entry DOI: 10.7270/Q29C6ZWQ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%