Affinity Data by PubMed id=24098954

PubMed code 24098954

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441948 (CHEMBL2440299) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441952 (CHEMBL2440297) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441939 (CHEMBL2440321) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441947 (CHEMBL2440307) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441949 (CHEMBL2440298) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441951 (CHEMBL2440120) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441950 (CHEMBL2440296) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441941 (CHEMBL2440319) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441943 (CHEMBL2440313) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441944 (CHEMBL2440311) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441945 (CHEMBL2440310) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441946 (CHEMBL2440308) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441942 (CHEMBL2440317) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	560	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441940 (CHEMBL2440320) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
University of California at Irvine Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%