Affinity Data by PubMed id=24147804

PubMed code 24147804

Found 17 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443300 (CHEMBL3088230) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	323	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Displacement of FITC-ATRIP2 from RPA70NAB domain (unknown origin) by FPA assay				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443305 (CHEMBL3088226) Show SMILES OC(=O)c1ccc(o1)-c1ccc(F)c(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	1.40E+6	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N (1 to 120) site2 (unknown origin) expressed in Escherichia coli BL21-DE3 cells by NMR spectroscopy				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443302 (CHEMBL3088229) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N (1 to 120) (unknown origin) expressed in Escherichia coli BL21-DE3 cells by FPA assay				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443300 (CHEMBL3088230) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70NAB (unknown origin) by FPA assay				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443302 (CHEMBL3088229) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N (1 to 120) (unknown origin) expressed in Escherichia coli BL21-DE3 cells by NMR spectroscopy				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50437283 (CHEMBL449442) Show SMILES Clc1ccc(cc1)-c1nnn[nH]1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.85E+6	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N (1 to 120) site1 (unknown origin) expressed in Escherichia coli BL21-DE3 cells by NMR spectroscopy				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50424720 (CHEMBL2314511) Show SMILES Cc1cccc2c(c([nH]c12)C(O)=O)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	6.40E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N (1 to 120) site1 (unknown origin) expressed in Escherichia coli BL21-DE3 cells by NMR spectroscopy				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443300 (CHEMBL3088230) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Displacement of FITC-ATRIP2 from RPA70N (1 to 120) (unknown origin) by FPA assay				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443305 (CHEMBL3088226) Show SMILES OC(=O)c1ccc(o1)-c1ccc(F)c(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	7.10E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N (1 to 120) site1 (unknown origin) expressed in Escherichia coli BL21-DE3 cells by NMR spectroscopy				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443300 (CHEMBL3088230) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Displacement of FITC-ss-DNA from RPA70AB domain (unknown origin) by FPA assay				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443303 (CHEMBL3088228) Show SMILES CCc1c(O)nc2[nH]c3ccccc3n2c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.62E+6	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N (1 to 120) site2 (unknown origin) expressed in Escherichia coli BL21-DE3 cells by NMR spectroscopy				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443304 (CHEMBL3088227) Show SMILES Cc1cccc(c1)-n1nc(cc1-c1ccccc1)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	>2.00E+6	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N (1 to 120) site2 (unknown origin) expressed in Escherichia coli BL21-DE3 cells by NMR spectroscopy				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443304 (CHEMBL3088227) Show SMILES Cc1cccc(c1)-n1nc(cc1-c1ccccc1)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	5.80E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N (1 to 120) site1 (unknown origin) expressed in Escherichia coli BL21-DE3 cells by NMR spectroscopy				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443300 (CHEMBL3088230) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N (1 to 120) (unknown origin) expressed in Escherichia coli BL21-DE3 cells by FPA assay				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM45821 (3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid \|...) Show SMILES OC(=O)c1cc(n[nH]1)-c1ccc(F)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.12E+6	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N (1 to 120) site2 (unknown origin) expressed in Escherichia coli BL21-DE3 cells by NMR spectroscopy				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443300 (CHEMBL3088230) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Displacement of FITC-ss-DNA from RPA70NAB domain (unknown origin) by FPA assay				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50443301 (CHEMBL3088231) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to RPA70N (1 to 120) (unknown origin) expressed in Escherichia coli BL21-DE3 cells by NMR spectroscopy				J Med Chem 56: 9242-50 (2013) Article DOI: 10.1021/jm401333u BindingDB Entry DOI: 10.7270/Q2B56M5D
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%