Affinity Data by PubMed id=24200808

PubMed code 24200808

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50428449 (CHEMBL449451) Show SMILES COc1ccc(cc1F)-c1ccc(O)c(CN=O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human H1299 cells assessed as inhibition of 2-deoxy-D-[3H]-glucose uptake incubated for 15 mins prior to 2-deoxy-D-[3H]-glucos...				Bioorg Med Chem Lett 23: 6923-7 (2013) Article DOI: 10.1016/j.bmcl.2013.09.037 BindingDB Entry DOI: 10.7270/Q2639R6Q
Universit£ di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50428447 (CHEMBL479638) Show SMILES CC(N=O)c1ccc(-c2ccc(O)cc2)c(Cl)c1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human H1299 cells assessed as inhibition of 2-deoxy-D-[3H]-glucose uptake incubated for 15 mins prior to 2-deoxy-D-[3H]-glucos...				Bioorg Med Chem Lett 23: 6923-7 (2013) Article DOI: 10.1016/j.bmcl.2013.09.037 BindingDB Entry DOI: 10.7270/Q2639R6Q
Universit£ di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50444088 (CHEMBL3092944) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human H1299 cells assessed as inhibition of 2-deoxy-D-[3H]-glucose uptake incubated for 15 mins prior to 2-deoxy-D-[3H]-glucos...				Bioorg Med Chem Lett 23: 6923-7 (2013) Article DOI: 10.1016/j.bmcl.2013.09.037 BindingDB Entry DOI: 10.7270/Q2639R6Q
Universit£ di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50444086 (CHEMBL479837) Show SMILES COc1ccc(cc1F)-c1ccc(C(C)N=O)c(O)c1Cl Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human H1299 cells assessed as inhibition of 2-deoxy-D-[3H]-glucose uptake incubated for 15 mins prior to 2-deoxy-D-[3H]-glucos...				Bioorg Med Chem Lett 23: 6923-7 (2013) Article DOI: 10.1016/j.bmcl.2013.09.037 BindingDB Entry DOI: 10.7270/Q2639R6Q
Universit£ di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM23446 (3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop...) Show SMILES Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human H1299 cells assessed as inhibition of 2-deoxy-D-[3H]-glucose uptake incubated for 15 mins prior to 2-deoxy-D-[3H]-glucos...				Bioorg Med Chem Lett 23: 6923-7 (2013) Article DOI: 10.1016/j.bmcl.2013.09.037 BindingDB Entry DOI: 10.7270/Q2639R6Q
Universit£ di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50444087 (CHEMBL480612) Show SMILES COc1ccc(cc1)-c1ccc(O)c(CN=O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human H1299 cells assessed as inhibition of 2-deoxy-D-[3H]-glucose uptake incubated for 15 mins prior to 2-deoxy-D-[3H]-glucos...				Bioorg Med Chem Lett 23: 6923-7 (2013) Article DOI: 10.1016/j.bmcl.2013.09.037 BindingDB Entry DOI: 10.7270/Q2639R6Q
Universit£ di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%