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PubMed code 24900747

Compile data set for download or QSAR
Found 25 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437410
PNG
(CHEMBL2409030)
Show SMILES CCOCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1ccncc1
Show InChI InChI=1S/C22H22N6O2S/c1-3-30-14-18-17(21(29)24-12-16-6-8-23-9-7-16)13-26-28(18)22-25-11-15(2)20(27-22)19-5-4-10-31-19/h4-11,13H,3,12,14H2,1-2H3,(H,24,29)
KEGG

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n/an/an/an/a 30n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437428
PNG
(CHEMBL2409025)
Show SMILES CCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1ccncc1
Show InChI InChI=1S/C21H20N6OS/c1-3-17-16(20(28)23-12-15-6-8-22-9-7-15)13-25-27(17)21-24-11-14(2)19(26-21)18-5-4-10-29-18/h4-11,13H,3,12H2,1-2H3,(H,23,28)
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n/an/an/an/a 1.00E+3n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437420
PNG
(CHEMBL2409014)
Show SMILES CCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1cncn1CC(O)=O
Show InChI InChI=1S/C23H25N7O3S/c1-3-4-6-18-17(22(33)25-11-16-10-24-14-29(16)13-20(31)32)12-27-30(18)23-26-9-15(2)21(28-23)19-7-5-8-34-19/h5,7-10,12,14H,3-4,6,11,13H2,1-2H3,(H,25,33)(H,31,32)
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n/an/an/an/a 0.200n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437414
PNG
(CHEMBL2409023)
Show SMILES CCOCc1c(cnn1-c1ncc(C)c(n1)N1CCCC1)C(=O)NCc1cncn1C
Show InChI InChI=1S/C21H28N8O2/c1-4-31-13-18-17(20(30)23-11-16-10-22-14-27(16)3)12-25-29(18)21-24-9-15(2)19(26-21)28-7-5-6-8-28/h9-10,12,14H,4-8,11,13H2,1-3H3,(H,23,30)
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n/an/an/an/a 14n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437416
PNG
(CHEMBL2409031)
Show SMILES CCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NC(C)(C)c1ccncc1
Show InChI InChI=1S/C24H26N6OS/c1-5-7-19-18(22(31)29-24(3,4)17-9-11-25-12-10-17)15-27-30(19)23-26-14-16(2)21(28-23)20-8-6-13-32-20/h6,8-15H,5,7H2,1-4H3,(H,29,31)
KEGG

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n/an/an/an/a 5n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437429
PNG
(CHEMBL2409026)
Show SMILES CCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1ccncc1
Show InChI InChI=1S/C22H22N6OS/c1-3-5-18-17(21(29)24-13-16-7-9-23-10-8-16)14-26-28(18)22-25-12-15(2)20(27-22)19-6-4-11-30-19/h4,6-12,14H,3,5,13H2,1-2H3,(H,24,29)
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n/an/an/an/a 250n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437430
PNG
(CHEMBL2409017)
Show SMILES CCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1sc(C)nc1C
Show InChI InChI=1S/C23H26N6OS2/c1-5-6-8-18-17(22(30)24-13-20-15(3)27-16(4)32-20)12-26-29(18)23-25-11-14(2)21(28-23)19-9-7-10-31-19/h7,9-12H,5-6,8,13H2,1-4H3,(H,24,30)
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n/an/an/an/a 200n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437432
PNG
(CHEMBL2409020)
Show SMILES CCOCc1c(cnn1-c1ncc(C)c(OCC)n1)C(=O)NCc1cncn1C
Show InChI InChI=1S/C19H25N7O3/c1-5-28-11-16-15(17(27)21-9-14-8-20-12-25(14)4)10-23-26(16)19-22-7-13(3)18(24-19)29-6-2/h7-8,10,12H,5-6,9,11H2,1-4H3,(H,21,27)
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n/an/an/an/a 96n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437411
PNG
(CHEMBL2409022)
Show SMILES CCOCc1c(cnn1-c1ncc(C)c(n1)N1CCC1)C(=O)NCc1cncn1C
Show InChI InChI=1S/C20H26N8O2/c1-4-30-12-17-16(19(29)22-10-15-9-21-13-26(15)3)11-24-28(17)20-23-8-14(2)18(25-20)27-6-5-7-27/h8-9,11,13H,4-7,10,12H2,1-3H3,(H,22,29)
KEGG

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n/an/an/an/a 28n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437413
PNG
(CHEMBL2409007)
Show SMILES CCOCc1c(cnn1-c1ncc(C)c(n1)N1CCCCC1)C(=O)NCc1cncn1C
Show InChI InChI=1S/C22H30N8O2/c1-4-32-14-19-18(21(31)24-12-17-11-23-15-28(17)3)13-26-30(19)22-25-10-16(2)20(27-22)29-8-6-5-7-9-29/h10-11,13,15H,4-9,12,14H2,1-3H3,(H,24,31)
KEGG

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n/an/an/an/a 22n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437419
PNG
(CHEMBL2409009)
Show SMILES CCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1cncn1C
Show InChI InChI=1S/C22H25N7OS/c1-4-5-7-18-17(21(30)24-12-16-11-23-14-28(16)3)13-26-29(18)22-25-10-15(2)20(27-22)19-8-6-9-31-19/h6,8-11,13-14H,4-5,7,12H2,1-3H3,(H,24,30)
KEGG

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n/an/an/an/a 1n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437422
PNG
(CHEMBL2409016)
Show SMILES CCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1cc(C)no1
Show InChI InChI=1S/C21H22N6O2S/c1-4-6-17-16(20(28)22-11-15-9-14(3)26-29-15)12-24-27(17)21-23-10-13(2)19(25-21)18-7-5-8-30-18/h5,7-10,12H,4,6,11H2,1-3H3,(H,22,28)
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n/an/an/an/a>2.00E+4n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437431
PNG
(CHEMBL2409013)
Show SMILES CCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NC1CCCc2ncn(C)c12
Show InChI InChI=1S/C25H29N7OS/c1-4-5-10-20-17(24(33)29-19-9-6-8-18-23(19)31(3)15-27-18)14-28-32(20)25-26-13-16(2)22(30-25)21-11-7-12-34-21/h7,11-15,19H,4-6,8-10H2,1-3H3,(H,29,33)
KEGG

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n/an/an/an/a 100n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437433
PNG
(CHEMBL2409015)
Show SMILES CCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1ccnn1C
Show InChI InChI=1S/C22H25N7OS/c1-4-5-7-18-17(21(30)23-13-16-9-10-25-28(16)3)14-26-29(18)22-24-12-15(2)20(27-22)19-8-6-11-31-19/h6,8-12,14H,4-5,7,13H2,1-3H3,(H,23,30)
KEGG

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n/an/an/an/a 90n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437412
PNG
(CHEMBL2409021)
Show SMILES CCOCc1c(cnn1-c1ncc(C)c(NC2CCC2)n1)C(=O)NCc1cncn1C
Show InChI InChI=1S/C21H28N8O2/c1-4-31-12-18-17(20(30)23-10-16-9-22-13-28(16)3)11-25-29(18)21-24-8-14(2)19(27-21)26-15-6-5-7-15/h8-9,11,13,15H,4-7,10,12H2,1-3H3,(H,23,30)(H,24,26,27)
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n/an/an/an/a 25n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437409
PNG
(CHEMBL2409012)
Show SMILES CCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1cnc(C)n1C
Show InChI InChI=1S/C23H27N7OS/c1-5-6-8-19-18(22(31)25-13-17-12-24-16(3)29(17)4)14-27-30(19)23-26-11-15(2)21(28-23)20-9-7-10-32-20/h7,9-12,14H,5-6,8,13H2,1-4H3,(H,25,31)
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n/an/an/an/a 30n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437417
PNG
(CHEMBL2409019)
Show SMILES CCOCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1cncn1C
Show InChI InChI=1S/C21H23N7O2S/c1-4-30-12-17-16(20(29)23-10-15-9-22-13-27(15)3)11-25-28(17)21-24-8-14(2)19(26-21)18-6-5-7-31-18/h5-9,11,13H,4,10,12H2,1-3H3,(H,23,29)
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n/an/an/an/a 1.30n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437418
PNG
(CHEMBL2409011)
Show SMILES CCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1c(C)ncn1C
Show InChI InChI=1S/C23H27N7OS/c1-5-6-8-18-17(22(31)24-13-19-16(3)26-14-29(19)4)12-27-30(18)23-25-11-15(2)21(28-23)20-9-7-10-32-20/h7,9-12,14H,5-6,8,13H2,1-4H3,(H,24,31)
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n/an/an/an/a 1n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437424
PNG
(CHEMBL2409032)
Show SMILES CCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)N(CC)Cc1ccncc1
Show InChI InChI=1S/C24H26N6OS/c1-4-7-20-19(23(31)29(5-2)16-18-9-11-25-12-10-18)15-27-30(20)24-26-14-17(3)22(28-24)21-8-6-13-32-21/h6,8-15H,4-5,7,16H2,1-3H3
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n/an/an/an/a 3.00E+3n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437426
PNG
(CHEMBL2409029)
Show SMILES CCC(C)c1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1ccncc1
Show InChI InChI=1S/C23H24N6OS/c1-4-15(2)21-18(22(30)25-13-17-7-9-24-10-8-17)14-27-29(21)23-26-12-16(3)20(28-23)19-6-5-11-31-19/h5-12,14-15H,4,13H2,1-3H3,(H,25,30)
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n/an/an/an/a 1.20E+3n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437427
PNG
(CHEMBL2409028)
Show SMILES CCCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1ccncc1
Show InChI InChI=1S/C24H26N6OS/c1-3-4-5-7-20-19(23(31)26-15-18-9-11-25-12-10-18)16-28-30(20)24-27-14-17(2)22(29-24)21-8-6-13-32-21/h6,8-14,16H,3-5,7,15H2,1-2H3,(H,26,31)
KEGG

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n/an/an/an/a 1.00E+3n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437423
PNG
(CHEMBL2409010)
Show SMILES CCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1cn(C)cn1
Show InChI InChI=1S/C21H23N7OS/c1-4-6-17-16(20(29)22-10-15-12-27(3)13-24-15)11-25-28(17)21-23-9-14(2)19(26-21)18-7-5-8-30-18/h5,7-9,11-13H,4,6,10H2,1-3H3,(H,22,29)
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n/an/an/an/a 1.50E+4n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437425
PNG
(CHEMBL2409024)
Show SMILES COCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1ccncc1
Show InChI InChI=1S/C21H20N6O2S/c1-14-10-24-21(26-19(14)18-4-3-9-30-18)27-17(13-29-2)16(12-25-27)20(28)23-11-15-5-7-22-8-6-15/h3-10,12H,11,13H2,1-2H3,(H,23,28)
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n/an/an/an/a 1.50E+3n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437421
PNG
(CHEMBL2409018)
Show SMILES CCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1c[nH]c2ccccc12
Show InChI InChI=1S/C26H26N6OS/c1-3-4-10-22-20(25(33)28-15-18-14-27-21-9-6-5-8-19(18)21)16-30-32(22)26-29-13-17(2)24(31-26)23-11-7-12-34-23/h5-9,11-14,16,27H,3-4,10,15H2,1-2H3,(H,28,33)
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n/an/an/an/a>2.00E+4n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))		BDBM50437415
PNG
(CHEMBL2409027)
Show SMILES CCCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1ccncc1
Show InChI InChI=1S/C23H24N6OS/c1-3-4-6-19-18(22(30)25-14-17-8-10-24-11-9-17)15-27-29(19)23-26-13-16(2)21(28-23)20-7-5-12-31-20/h5,7-13,15H,3-4,6,14H2,1-2H3,(H,25,30)
KEGG

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n/an/an/an/a 7n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay

ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%