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PubMed code 25261823

Compile data set for download or QSAR
Found 107 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099461
PNG
(CHEMBL3342871)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3cccc(c3)[N+]([O-])=O)O2)CC1
Show InChI InChI=1S/C25H32N4O7S/c1-34-24-8-3-2-7-23(24)27-15-13-26(14-16-27)18-21-19-35-25(36-21)9-11-28(12-10-25)37(32,33)22-6-4-5-20(17-22)29(30)31/h2-8,17,21H,9-16,18-19H2,1H3
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 0.912n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099461
PNG
(CHEMBL3342871)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3cccc(c3)[N+]([O-])=O)O2)CC1
Show InChI InChI=1S/C25H32N4O7S/c1-34-24-8-3-2-7-23(24)27-15-13-26(14-16-27)18-21-19-35-25(36-21)9-11-28(12-10-25)37(32,33)22-6-4-5-20(17-22)29(30)31/h2-8,17,21H,9-16,18-19H2,1H3
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 3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099457
PNG
(CHEMBL3342867)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(C)cc3)O2)CC1
Show InChI InChI=1S/C14H8N4O4/c19-13-12-15-8(14(20)21)5-18(12)11-9(16-13)6-3-1-2-4-7(6)10(11)17-22/h1-5,15,19H,(H,20,21)
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 4.60n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099437
PNG
(CHEMBL3342853)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(Cc4ccccc4)CC3)O2)CC1
Show InChI InChI=1S/C26H35N3O3/c1-30-25-10-6-5-9-24(25)29-17-15-28(16-18-29)20-23-21-31-26(32-23)11-13-27(14-12-26)19-22-7-3-2-4-8-22/h2-10,23H,11-21H2,1H3
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 4.70n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099434
PNG
(CHEMBL2234448)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCCCC3)O2)CC1
Show InChI InChI=1S/C20H30N2O3/c1-23-19-8-4-3-7-18(19)22-13-11-21(12-14-22)15-17-16-24-20(25-17)9-5-2-6-10-20/h3-4,7-8,17H,2,5-6,9-16H2,1H3
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 5.10n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099460
PNG
(CHEMBL3342870)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(cc3)[N+]([O-])=O)O2)CC1
Show InChI InChI=1S/C25H32N4O7S/c1-34-24-5-3-2-4-23(24)27-16-14-26(15-17-27)18-21-19-35-25(36-21)10-12-28(13-11-25)37(32,33)22-8-6-20(7-9-22)29(30)31/h2-9,21H,10-19H2,1H3
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PubMed
 5.20n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099460
PNG
(CHEMBL3342870)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(cc3)[N+]([O-])=O)O2)CC1
Show InChI InChI=1S/C25H32N4O7S/c1-34-24-5-3-2-4-23(24)27-16-14-26(15-17-27)18-21-19-35-25(36-21)10-12-28(13-11-25)37(32,33)22-8-6-20(7-9-22)29(30)31/h2-9,21H,10-19H2,1H3
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 5.80n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099441
PNG
(CHEMBL3342857)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)c3ccccc3)O2)CC1
Show InChI InChI=1S/C16H13FN2O3/c1-21-13-7-11-12(8-14(13)22-2)18-15(19-16(11)20)9-4-3-5-10(17)6-9/h3-8H,1-2H3,(H,18,19,20)
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 6.5n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099458
PNG
(CHEMBL3342868)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(Cl)cc3)O2)CC1
Show InChI InChI=1S/C14H15F3N3O6P/c15-14(16,17)8-5-9-11(6-10(8)19-1-3-26-4-2-19)20(7-27(23,24)25)13(22)12(21)18-9/h5-6H,1-4,7H2,(H,18,21)(H2,23,24,25)
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 6.5n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099437
PNG
(CHEMBL3342853)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(Cc4ccccc4)CC3)O2)CC1
Show InChI InChI=1S/C26H35N3O3/c1-30-25-10-6-5-9-24(25)29-17-15-28(16-18-29)20-23-21-31-26(32-23)11-13-27(14-12-26)19-22-7-3-2-4-8-22/h2-10,23H,11-21H2,1H3
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 6.80n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099458
PNG
(CHEMBL3342868)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(Cl)cc3)O2)CC1
Show InChI InChI=1S/C14H15F3N3O6P/c15-14(16,17)8-5-9-11(6-10(8)19-1-3-26-4-2-19)20(7-27(23,24)25)13(22)12(21)18-9/h5-6H,1-4,7H2,(H,18,21)(H2,23,24,25)
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 7.10n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099462
PNG
(CHEMBL3342872)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3cccs3)O2)CC1
Show InChI InChI=1S/C23H31N3O5S2/c1-29-21-6-3-2-5-20(21)25-14-12-24(13-15-25)17-19-18-30-23(31-19)8-10-26(11-9-23)33(27,28)22-7-4-16-32-22/h2-7,16,19H,8-15,17-18H2,1H3
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 7.90n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099456
PNG
(CHEMBL3342866)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccccc3)O2)CC1
Show InChI InChI=1S/C25H33N3O5S/c1-31-24-10-6-5-9-23(24)27-17-15-26(16-18-27)19-21-20-32-25(33-21)11-13-28(14-12-25)34(29,30)22-7-3-2-4-8-22/h2-10,21H,11-20H2,1H3
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 7.90n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099441
PNG
(CHEMBL3342857)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)c3ccccc3)O2)CC1
Show InChI InChI=1S/C16H13FN2O3/c1-21-13-7-11-12(8-14(13)22-2)18-15(19-16(11)20)9-4-3-5-10(17)6-9/h3-8H,1-2H3,(H,18,19,20)
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 8.10n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099457
PNG
(CHEMBL3342867)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(C)cc3)O2)CC1
Show InChI InChI=1S/C14H8N4O4/c19-13-12-15-8(14(20)21)5-18(12)11-9(16-13)6-3-1-2-4-7(6)10(11)17-22/h1-5,15,19H,(H,20,21)
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 8.30n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099435
PNG
(CHEMBL3342852)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCSCC3)O2)CC1
Show InChI InChI=1S/C19H28N2O3S/c1-22-18-5-3-2-4-17(18)21-10-8-20(9-11-21)14-16-15-23-19(24-16)6-12-25-13-7-19/h2-5,16H,6-15H2,1H3
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 8.5n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099442
PNG
(CHEMBL3342858)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)c3ccccn3)O2)CC1
Show InChI InChI=1S/C14H9FN2O/c15-10-5-3-4-9(8-10)13-16-12-7-2-1-6-11(12)14(18)17-13/h1-8H,(H,16,17,18)
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 8.90n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099459
PNG
(CHEMBL3342869)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(OC(F)(F)F)cc3)O2)CC1
Show InChI InChI=1S/C18H14N4O6/c23-12(24)6-3-7-28-21-14-10-5-2-1-4-9(10)13-15(14)22-8-11(18(26)27)19-16(22)17(25)20-13/h1-2,4-5,8H,3,6-7H2,(H,20,25)(H,23,24)(H,26,27)/b21-14+
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 8.90n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099435
PNG
(CHEMBL3342852)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCSCC3)O2)CC1
Show InChI InChI=1S/C19H28N2O3S/c1-22-18-5-3-2-4-17(18)21-10-8-20(9-11-21)14-16-15-23-19(24-16)6-12-25-13-7-19/h2-5,16H,6-15H2,1H3
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 9.30n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099439
PNG
(CHEMBL3342855)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCS(=O)(=O)CC3)O2)CC1
Show InChI InChI=1S/C18H12N2O/c21-18-15-7-3-4-8-16(15)19-17(20-18)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H,19,20,21)
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 9.80n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099462
PNG
(CHEMBL3342872)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3cccs3)O2)CC1
Show InChI InChI=1S/C23H31N3O5S2/c1-29-21-6-3-2-5-20(21)25-14-12-24(13-15-25)17-19-18-30-23(31-19)8-10-26(11-9-23)33(27,28)22-7-4-16-32-22/h2-7,16,19H,8-15,17-18H2,1H3
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 9.80n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099444
PNG
(CHEMBL3342860)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)c3ccc(cc3)C(F)(F)F)O2)CC1
Show InChI InChI=1S/C20H16N2O3/c1-24-17-10-15-16(11-18(17)25-2)21-19(22-20(15)23)14-8-7-12-5-3-4-6-13(12)9-14/h3-11H,1-2H3,(H,21,22,23)
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 10n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099444
PNG
(CHEMBL3342860)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)c3ccc(cc3)C(F)(F)F)O2)CC1
Show InChI InChI=1S/C20H16N2O3/c1-24-17-10-15-16(11-18(17)25-2)21-19(22-20(15)23)14-8-7-12-5-3-4-6-13(12)9-14/h3-11H,1-2H3,(H,21,22,23)
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 11n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099457
PNG
(CHEMBL3342867)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(C)cc3)O2)CC1
Show InChI InChI=1S/C14H8N4O4/c19-13-12-15-8(14(20)21)5-18(12)11-9(16-13)6-3-1-2-4-7(6)10(11)17-22/h1-5,15,19H,(H,20,21)
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 11n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099443
PNG
(CHEMBL3342859)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)c3ccccc3)O2)CC1
Show InChI InChI=1S/C14H9FN2O/c15-10-7-5-9(6-8-10)13-16-12-4-2-1-3-11(12)14(18)17-13/h1-8H,(H,16,17,18)
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 11n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099456
PNG
(CHEMBL3342866)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccccc3)O2)CC1
Show InChI InChI=1S/C25H33N3O5S/c1-31-24-10-6-5-9-23(24)27-17-15-26(16-18-27)19-21-20-32-25(33-21)11-13-28(14-12-25)34(29,30)22-7-3-2-4-8-22/h2-10,21H,11-20H2,1H3
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 12n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099453
PNG
(CHEMBL3342863)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)C3CCCN3)O2)CC1
Show InChI InChI=1S/C24H36N4O4/c1-30-22-7-3-2-6-21(22)27-15-13-26(14-16-27)17-19-18-31-24(32-19)8-11-28(12-9-24)23(29)20-5-4-10-25-20/h2-3,6-7,19-20,25H,4-5,8-18H2,1H3
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 12n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099473
PNG
(CHEMBL3342874)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)Nc3ccccc3)O2)CC1
Show InChI InChI=1S/C26H34N4O4/c1-32-24-10-6-5-9-23(24)29-17-15-28(16-18-29)19-22-20-33-26(34-22)11-13-30(14-12-26)25(31)27-21-7-3-2-4-8-21/h2-10,22H,11-20H2,1H3,(H,27,31)
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 12n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099473
PNG
(CHEMBL3342874)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)Nc3ccccc3)O2)CC1
Show InChI InChI=1S/C26H34N4O4/c1-32-24-10-6-5-9-23(24)29-17-15-28(16-18-29)19-22-20-33-26(34-22)11-13-30(14-12-26)25(31)27-21-7-3-2-4-8-21/h2-10,22H,11-20H2,1H3,(H,27,31)
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 13n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099565
PNG
(CHEMBL3342876)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)NC(C)(C)C)O2)CC1
Show InChI InChI=1S/C24H38N4O4/c1-23(2,3)25-22(29)28-11-9-24(10-12-28)31-18-19(32-24)17-26-13-15-27(16-14-26)20-7-5-6-8-21(20)30-4/h5-8,19H,9-18H2,1-4H3,(H,25,29)
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 13n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099437
PNG
(CHEMBL3342853)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(Cc4ccccc4)CC3)O2)CC1
Show InChI InChI=1S/C26H35N3O3/c1-30-25-10-6-5-9-24(25)29-17-15-28(16-18-29)20-23-21-31-26(32-23)11-13-27(14-12-26)19-22-7-3-2-4-8-22/h2-10,23H,11-21H2,1H3
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 14n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099435
PNG
(CHEMBL3342852)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCSCC3)O2)CC1
Show InChI InChI=1S/C19H28N2O3S/c1-22-18-5-3-2-4-17(18)21-10-8-20(9-11-21)14-16-15-23-19(24-16)6-12-25-13-7-19/h2-5,16H,6-15H2,1H3
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 15n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099441
PNG
(CHEMBL3342857)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)c3ccccc3)O2)CC1
Show InChI InChI=1S/C16H13FN2O3/c1-21-13-7-11-12(8-14(13)22-2)18-15(19-16(11)20)9-4-3-5-10(17)6-9/h3-8H,1-2H3,(H,18,19,20)
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 16n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099437
PNG
(CHEMBL3342853)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(Cc4ccccc4)CC3)O2)CC1
Show InChI InChI=1S/C26H35N3O3/c1-30-25-10-6-5-9-24(25)29-17-15-28(16-18-29)20-23-21-31-26(32-23)11-13-27(14-12-26)19-22-7-3-2-4-8-22/h2-10,23H,11-21H2,1H3
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 17n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099436
PNG
(CHEMBL3341769)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCOCC3)O2)CC1
Show InChI InChI=1S/C19H28N2O4/c1-22-18-5-3-2-4-17(18)21-10-8-20(9-11-21)14-16-15-24-19(25-16)6-12-23-13-7-19/h2-5,16H,6-15H2,1H3
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 17n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099442
PNG
(CHEMBL3342858)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)c3ccccn3)O2)CC1
Show InChI InChI=1S/C14H9FN2O/c15-10-5-3-4-9(8-10)13-16-12-7-2-1-6-11(12)14(18)17-13/h1-8H,(H,16,17,18)
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 18n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099472
PNG
(CHEMBL3342873)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(C)(=O)=O)O2)CC1
Show InChI InChI=1S/C20H31N3O5S/c1-26-19-6-4-3-5-18(19)22-13-11-21(12-14-22)15-17-16-27-20(28-17)7-9-23(10-8-20)29(2,24)25/h3-6,17H,7-16H2,1-2H3
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 19n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099557
PNG
(CHEMBL3342875)
Show SMILES CCCCNC(=O)N1CCC2(CC1)OCC(CN1CCN(CC1)c1ccccc1OC)O2
Show InChI InChI=1S/C37H50N2O10/c1-7-38-17-34(18-49-32(42)20-10-8-9-11-23(20)39-26(40)14-19(2)31(39)41)13-12-25(46-4)36-22-15-21-24(45-3)16-35(43,27(22)28(21)47-5)37(44,33(36)38)30(48-6)29(34)36/h8-11,19,21-22,24-25,27-30,33,43-44H,7,12-18H2,1-6H3/t19-,21?,22+,24-,25-,27+,28-,29+,30-,33?,34?,35+,36?,37?/m0/s1
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 19n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099446
PNG
(CHEMBL3342862)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)C3CCCCC3)O2)CC1
Show InChI InChI=1S/C16H13FN2O3/c1-21-13-7-11-12(8-14(13)22-2)18-15(19-16(11)20)9-3-5-10(17)6-4-9/h3-8H,1-2H3,(H,18,19,20)
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 20n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099443
PNG
(CHEMBL3342859)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)c3ccccc3)O2)CC1
Show InChI InChI=1S/C14H9FN2O/c15-10-7-5-9(6-8-10)13-16-12-4-2-1-3-11(12)14(18)17-13/h1-8H,(H,16,17,18)
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 20n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099557
PNG
(CHEMBL3342875)
Show SMILES CCCCNC(=O)N1CCC2(CC1)OCC(CN1CCN(CC1)c1ccccc1OC)O2
Show InChI InChI=1S/C37H50N2O10/c1-7-38-17-34(18-49-32(42)20-10-8-9-11-23(20)39-26(40)14-19(2)31(39)41)13-12-25(46-4)36-22-15-21-24(45-3)16-35(43,27(22)28(21)47-5)37(44,33(36)38)30(48-6)29(34)36/h8-11,19,21-22,24-25,27-30,33,43-44H,7,12-18H2,1-6H3/t19-,21?,22+,24-,25-,27+,28-,29+,30-,33?,34?,35+,36?,37?/m0/s1
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 20n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099445
PNG
(CHEMBL3342861)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)c3ccco3)O2)CC1
Show InChI InChI=1S/C14H9FN2O/c15-11-7-3-1-5-9(11)13-16-12-8-4-2-6-10(12)14(18)17-13/h1-8H,(H,16,17,18)
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 21n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099472
PNG
(CHEMBL3342873)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(C)(=O)=O)O2)CC1
Show InChI InChI=1S/C20H31N3O5S/c1-26-19-6-4-3-5-18(19)22-13-11-21(12-14-22)15-17-16-27-20(28-17)7-9-23(10-8-20)29(2,24)25/h3-6,17H,7-16H2,1-2H3
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 23n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099442
PNG
(CHEMBL3342858)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)c3ccccn3)O2)CC1
Show InChI InChI=1S/C14H9FN2O/c15-10-5-3-4-9(8-10)13-16-12-7-2-1-6-11(12)14(18)17-13/h1-8H,(H,16,17,18)
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 23n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099460
PNG
(CHEMBL3342870)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(cc3)[N+]([O-])=O)O2)CC1
Show InChI InChI=1S/C25H32N4O7S/c1-34-24-5-3-2-4-23(24)27-16-14-26(15-17-27)18-21-19-35-25(36-21)10-12-28(13-11-25)37(32,33)22-8-6-20(7-9-22)29(30)31/h2-9,21H,10-19H2,1H3
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 25n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099436
PNG
(CHEMBL3341769)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCOCC3)O2)CC1
Show InChI InChI=1S/C19H28N2O4/c1-22-18-5-3-2-4-17(18)21-10-8-20(9-11-21)14-16-15-24-19(25-16)6-12-23-13-7-19/h2-5,16H,6-15H2,1H3
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 25n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099459
PNG
(CHEMBL3342869)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(OC(F)(F)F)cc3)O2)CC1
Show InChI InChI=1S/C18H14N4O6/c23-12(24)6-3-7-28-21-14-10-5-2-1-4-9(10)13-15(14)22-8-11(18(26)27)19-16(22)17(25)20-13/h1-2,4-5,8H,3,6-7H2,(H,20,25)(H,23,24)(H,26,27)/b21-14+
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 26n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099453
PNG
(CHEMBL3342863)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)C3CCCN3)O2)CC1
Show InChI InChI=1S/C24H36N4O4/c1-30-22-7-3-2-6-21(22)27-15-13-26(14-16-27)17-19-18-31-24(32-19)8-11-28(12-9-24)23(29)20-5-4-10-25-20/h2-3,6-7,19-20,25H,4-5,8-18H2,1H3
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 27n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099457
PNG
(CHEMBL3342867)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(C)cc3)O2)CC1
Show InChI InChI=1S/C14H8N4O4/c19-13-12-15-8(14(20)21)5-18(12)11-9(16-13)6-3-1-2-4-7(6)10(11)17-22/h1-5,15,19H,(H,20,21)
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 27n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099445
PNG
(CHEMBL3342861)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)c3ccco3)O2)CC1
Show InChI InChI=1S/C14H9FN2O/c15-11-7-3-1-5-9(11)13-16-12-8-4-2-6-10(12)14(18)17-13/h1-8H,(H,16,17,18)
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 28n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099446
PNG
(CHEMBL3342862)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)C3CCCCC3)O2)CC1
Show InChI InChI=1S/C16H13FN2O3/c1-21-13-7-11-12(8-14(13)22-2)18-15(19-16(11)20)9-3-5-10(17)6-4-9/h3-8H,1-2H3,(H,18,19,20)
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 31n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099473
PNG
(CHEMBL3342874)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)Nc3ccccc3)O2)CC1
Show InChI InChI=1S/C26H34N4O4/c1-32-24-10-6-5-9-23(24)29-17-15-28(16-18-29)19-22-20-33-26(34-22)11-13-30(14-12-26)25(31)27-21-7-3-2-4-8-21/h2-10,22H,11-20H2,1H3,(H,27,31)
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 33n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099565
PNG
(CHEMBL3342876)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)NC(C)(C)C)O2)CC1
Show InChI InChI=1S/C24H38N4O4/c1-23(2,3)25-22(29)28-11-9-24(10-12-28)31-18-19(32-24)17-26-13-15-27(16-14-26)20-7-5-6-8-21(20)30-4/h5-8,19H,9-18H2,1-4H3,(H,25,29)
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 35n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099453
PNG
(CHEMBL3342863)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)C3CCCN3)O2)CC1
Show InChI InChI=1S/C24H36N4O4/c1-30-22-7-3-2-6-21(22)27-15-13-26(14-16-27)17-19-18-31-24(32-19)8-11-28(12-9-24)23(29)20-5-4-10-25-20/h2-3,6-7,19-20,25H,4-5,8-18H2,1H3
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 36n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099440
PNG
(CHEMBL3342856)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCNCC3)O2)CC1
Show InChI InChI=1S/C16H13FN2O3/c1-21-13-7-10-12(8-14(13)22-2)18-15(19-16(10)20)9-5-3-4-6-11(9)17/h3-8H,1-2H3,(H,18,19,20)
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 37n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099458
PNG
(CHEMBL3342868)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(Cl)cc3)O2)CC1
Show InChI InChI=1S/C14H15F3N3O6P/c15-14(16,17)8-5-9-11(6-10(8)19-1-3-26-4-2-19)20(7-27(23,24)25)13(22)12(21)18-9/h5-6H,1-4,7H2,(H,18,21)(H2,23,24,25)
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 37n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099446
PNG
(CHEMBL3342862)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)C3CCCCC3)O2)CC1
Show InChI InChI=1S/C16H13FN2O3/c1-21-13-7-11-12(8-14(13)22-2)18-15(19-16(11)20)9-3-5-10(17)6-4-9/h3-8H,1-2H3,(H,18,19,20)
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 40n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099445
PNG
(CHEMBL3342861)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)c3ccco3)O2)CC1
Show InChI InChI=1S/C14H9FN2O/c15-11-7-3-1-5-9(11)13-16-12-8-4-2-6-10(12)14(18)17-13/h1-8H,(H,16,17,18)
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 43n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099438
PNG
(CHEMBL3342854)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CC[S+]([O-])CC3)O2)CC1
Show InChI InChI=1S/C19H28N2O4S/c1-23-18-5-3-2-4-17(18)21-10-8-20(9-11-21)14-16-15-24-19(25-16)6-12-26(22)13-7-19/h2-5,16H,6-15H2,1H3
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 43n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099440
PNG
(CHEMBL3342856)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCNCC3)O2)CC1
Show InChI InChI=1S/C16H13FN2O3/c1-21-13-7-10-12(8-14(13)22-2)18-15(19-16(10)20)9-5-3-4-6-11(9)17/h3-8H,1-2H3,(H,18,19,20)
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 43n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099461
PNG
(CHEMBL3342871)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3cccc(c3)[N+]([O-])=O)O2)CC1
Show InChI InChI=1S/C25H32N4O7S/c1-34-24-8-3-2-7-23(24)27-15-13-26(14-16-27)18-21-19-35-25(36-21)9-11-28(12-10-25)37(32,33)22-6-4-5-20(17-22)29(30)31/h2-8,17,21H,9-16,18-19H2,1H3
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 44n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099436
PNG
(CHEMBL3341769)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCOCC3)O2)CC1
Show InChI InChI=1S/C19H28N2O4/c1-22-18-5-3-2-4-17(18)21-10-8-20(9-11-21)14-16-15-24-19(25-16)6-12-23-13-7-19/h2-5,16H,6-15H2,1H3
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 47n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099440
PNG
(CHEMBL3342856)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCNCC3)O2)CC1
Show InChI InChI=1S/C16H13FN2O3/c1-21-13-7-10-12(8-14(13)22-2)18-15(19-16(10)20)9-5-3-4-6-11(9)17/h3-8H,1-2H3,(H,18,19,20)
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 49n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099444
PNG
(CHEMBL3342860)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)c3ccc(cc3)C(F)(F)F)O2)CC1
Show InChI InChI=1S/C20H16N2O3/c1-24-17-10-15-16(11-18(17)25-2)21-19(22-20(15)23)14-8-7-12-5-3-4-6-13(12)9-14/h3-11H,1-2H3,(H,21,22,23)
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 50n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099439
PNG
(CHEMBL3342855)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCS(=O)(=O)CC3)O2)CC1
Show InChI InChI=1S/C18H12N2O/c21-18-15-7-3-4-8-16(15)19-17(20-18)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H,19,20,21)
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 51n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099456
PNG
(CHEMBL3342866)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccccc3)O2)CC1
Show InChI InChI=1S/C25H33N3O5S/c1-31-24-10-6-5-9-23(24)27-17-15-26(16-18-27)19-21-20-32-25(33-21)11-13-28(14-12-25)34(29,30)22-7-3-2-4-8-22/h2-10,21H,11-20H2,1H3
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 52n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099443
PNG
(CHEMBL3342859)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)c3ccccc3)O2)CC1
Show InChI InChI=1S/C14H9FN2O/c15-10-7-5-9(6-8-10)13-16-12-4-2-1-3-11(12)14(18)17-13/h1-8H,(H,16,17,18)
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 59n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099454
PNG
(CHEMBL3342864)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(C)=O)O2)CC1
Show InChI InChI=1S/C21H31N3O4/c1-17(25)23-9-7-21(8-10-23)27-16-18(28-21)15-22-11-13-24(14-12-22)19-5-3-4-6-20(19)26-2/h3-6,18H,7-16H2,1-2H3
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 60n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099462
PNG
(CHEMBL3342872)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3cccs3)O2)CC1
Show InChI InChI=1S/C23H31N3O5S2/c1-29-21-6-3-2-5-20(21)25-14-12-24(13-15-25)17-19-18-30-23(31-19)8-10-26(11-9-23)33(27,28)22-7-4-16-32-22/h2-7,16,19H,8-15,17-18H2,1H3
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 60n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099444
PNG
(CHEMBL3342860)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)c3ccc(cc3)C(F)(F)F)O2)CC1
Show InChI InChI=1S/C20H16N2O3/c1-24-17-10-15-16(11-18(17)25-2)21-19(22-20(15)23)14-8-7-12-5-3-4-6-13(12)9-14/h3-11H,1-2H3,(H,21,22,23)
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 63n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099454
PNG
(CHEMBL3342864)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(C)=O)O2)CC1
Show InChI InChI=1S/C21H31N3O4/c1-17(25)23-9-7-21(8-10-23)27-16-18(28-21)15-22-11-13-24(14-12-22)19-5-3-4-6-20(19)26-2/h3-6,18H,7-16H2,1-2H3
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 65n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099443
PNG
(CHEMBL3342859)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)c3ccccc3)O2)CC1
Show InChI InChI=1S/C14H9FN2O/c15-10-7-5-9(6-8-10)13-16-12-4-2-1-3-11(12)14(18)17-13/h1-8H,(H,16,17,18)
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 68n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099459
PNG
(CHEMBL3342869)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(OC(F)(F)F)cc3)O2)CC1
Show InChI InChI=1S/C18H14N4O6/c23-12(24)6-3-7-28-21-14-10-5-2-1-4-9(10)13-15(14)22-8-11(18(26)27)19-16(22)17(25)20-13/h1-2,4-5,8H,3,6-7H2,(H,20,25)(H,23,24)(H,26,27)/b21-14+
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 69n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099458
PNG
(CHEMBL3342868)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(Cl)cc3)O2)CC1
Show InChI InChI=1S/C14H15F3N3O6P/c15-14(16,17)8-5-9-11(6-10(8)19-1-3-26-4-2-19)20(7-27(23,24)25)13(22)12(21)18-9/h5-6H,1-4,7H2,(H,18,21)(H2,23,24,25)
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 69n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099461
PNG
(CHEMBL3342871)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3cccc(c3)[N+]([O-])=O)O2)CC1
Show InChI InChI=1S/C25H32N4O7S/c1-34-24-8-3-2-7-23(24)27-15-13-26(14-16-27)18-21-19-35-25(36-21)9-11-28(12-10-25)37(32,33)22-6-4-5-20(17-22)29(30)31/h2-8,17,21H,9-16,18-19H2,1H3
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 69n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099557
PNG
(CHEMBL3342875)
Show SMILES CCCCNC(=O)N1CCC2(CC1)OCC(CN1CCN(CC1)c1ccccc1OC)O2
Show InChI InChI=1S/C37H50N2O10/c1-7-38-17-34(18-49-32(42)20-10-8-9-11-23(20)39-26(40)14-19(2)31(39)41)13-12-25(46-4)36-22-15-21-24(45-3)16-35(43,27(22)28(21)47-5)37(44,33(36)38)30(48-6)29(34)36/h8-11,19,21-22,24-25,27-30,33,43-44H,7,12-18H2,1-6H3/t19-,21?,22+,24-,25-,27+,28-,29+,30-,33?,34?,35+,36?,37?/m0/s1
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 79n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099439
PNG
(CHEMBL3342855)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCS(=O)(=O)CC3)O2)CC1
Show InChI InChI=1S/C18H12N2O/c21-18-15-7-3-4-8-16(15)19-17(20-18)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H,19,20,21)
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 81n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099473
PNG
(CHEMBL3342874)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)Nc3ccccc3)O2)CC1
Show InChI InChI=1S/C26H34N4O4/c1-32-24-10-6-5-9-23(24)29-17-15-28(16-18-29)19-22-20-33-26(34-22)11-13-30(14-12-26)25(31)27-21-7-3-2-4-8-21/h2-10,22H,11-20H2,1H3,(H,27,31)
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 81n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099456
PNG
(CHEMBL3342866)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccccc3)O2)CC1
Show InChI InChI=1S/C25H33N3O5S/c1-31-24-10-6-5-9-23(24)27-17-15-26(16-18-27)19-21-20-32-25(33-21)11-13-28(14-12-25)34(29,30)22-7-3-2-4-8-22/h2-10,21H,11-20H2,1H3
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 85n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099462
PNG
(CHEMBL3342872)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3cccs3)O2)CC1
Show InChI InChI=1S/C23H31N3O5S2/c1-29-21-6-3-2-5-20(21)25-14-12-24(13-15-25)17-19-18-30-23(31-19)8-10-26(11-9-23)33(27,28)22-7-4-16-32-22/h2-7,16,19H,8-15,17-18H2,1H3
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 85n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099565
PNG
(CHEMBL3342876)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)NC(C)(C)C)O2)CC1
Show InChI InChI=1S/C24H38N4O4/c1-23(2,3)25-22(29)28-11-9-24(10-12-28)31-18-19(32-24)17-26-13-15-27(16-14-26)20-7-5-6-8-21(20)30-4/h5-8,19H,9-18H2,1-4H3,(H,25,29)
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 87n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099454
PNG
(CHEMBL3342864)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(C)=O)O2)CC1
Show InChI InChI=1S/C21H31N3O4/c1-17(25)23-9-7-21(8-10-23)27-16-18(28-21)15-22-11-13-24(14-12-22)19-5-3-4-6-20(19)26-2/h3-6,18H,7-16H2,1-2H3
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 89n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099434
PNG
(CHEMBL2234448)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCCCC3)O2)CC1
Show InChI InChI=1S/C20H30N2O3/c1-23-19-8-4-3-7-18(19)22-13-11-21(12-14-22)15-17-16-24-20(25-17)9-5-2-6-10-20/h3-4,7-8,17H,2,5-6,9-16H2,1H3
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 91n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099460
PNG
(CHEMBL3342870)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(cc3)[N+]([O-])=O)O2)CC1
Show InChI InChI=1S/C25H32N4O7S/c1-34-24-5-3-2-4-23(24)27-16-14-26(15-17-27)18-21-19-35-25(36-21)10-12-28(13-11-25)37(32,33)22-8-6-20(7-9-22)29(30)31/h2-9,21H,10-19H2,1H3
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 110n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099446
PNG
(CHEMBL3342862)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)C3CCCCC3)O2)CC1
Show InChI InChI=1S/C16H13FN2O3/c1-21-13-7-11-12(8-14(13)22-2)18-15(19-16(11)20)9-3-5-10(17)6-4-9/h3-8H,1-2H3,(H,18,19,20)
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 110n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099438
PNG
(CHEMBL3342854)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CC[S+]([O-])CC3)O2)CC1
Show InChI InChI=1S/C19H28N2O4S/c1-23-18-5-3-2-4-17(18)21-10-8-20(9-11-21)14-16-15-24-19(25-16)6-12-26(22)13-7-19/h2-5,16H,6-15H2,1H3
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 117n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099434
PNG
(CHEMBL2234448)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCCCC3)O2)CC1
Show InChI InChI=1S/C20H30N2O3/c1-23-19-8-4-3-7-18(19)22-13-11-21(12-14-22)15-17-16-24-20(25-17)9-5-2-6-10-20/h3-4,7-8,17H,2,5-6,9-16H2,1H3
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 126n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099565
PNG
(CHEMBL3342876)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)NC(C)(C)C)O2)CC1
Show InChI InChI=1S/C24H38N4O4/c1-23(2,3)25-22(29)28-11-9-24(10-12-28)31-18-19(32-24)17-26-13-15-27(16-14-26)20-7-5-6-8-21(20)30-4/h5-8,19H,9-18H2,1-4H3,(H,25,29)
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 129n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099435
PNG
(CHEMBL3342852)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCSCC3)O2)CC1
Show InChI InChI=1S/C19H28N2O3S/c1-22-18-5-3-2-4-17(18)21-10-8-20(9-11-21)14-16-15-23-19(24-16)6-12-25-13-7-19/h2-5,16H,6-15H2,1H3
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 141n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099472
PNG
(CHEMBL3342873)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(C)(=O)=O)O2)CC1
Show InChI InChI=1S/C20H31N3O5S/c1-26-19-6-4-3-5-18(19)22-13-11-21(12-14-22)15-17-16-27-20(28-17)7-9-23(10-8-20)29(2,24)25/h3-6,17H,7-16H2,1-2H3
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 145n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099459
PNG
(CHEMBL3342869)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(OC(F)(F)F)cc3)O2)CC1
Show InChI InChI=1S/C18H14N4O6/c23-12(24)6-3-7-28-21-14-10-5-2-1-4-9(10)13-15(14)22-8-11(18(26)27)19-16(22)17(25)20-13/h1-2,4-5,8H,3,6-7H2,(H,20,25)(H,23,24)(H,26,27)/b21-14+
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 148n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099441
PNG
(CHEMBL3342857)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)c3ccccc3)O2)CC1
Show InChI InChI=1S/C16H13FN2O3/c1-21-13-7-11-12(8-14(13)22-2)18-15(19-16(11)20)9-4-3-5-10(17)6-9/h3-8H,1-2H3,(H,18,19,20)
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 155n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099445
PNG
(CHEMBL3342861)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)c3ccco3)O2)CC1
Show InChI InChI=1S/C14H9FN2O/c15-11-7-3-1-5-9(11)13-16-12-8-4-2-6-10(12)14(18)17-13/h1-8H,(H,16,17,18)
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 158n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099453
PNG
(CHEMBL3342863)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)C3CCCN3)O2)CC1
Show InChI InChI=1S/C24H36N4O4/c1-30-22-7-3-2-6-21(22)27-15-13-26(14-16-27)17-19-18-31-24(32-19)8-11-28(12-9-24)23(29)20-5-4-10-25-20/h2-3,6-7,19-20,25H,4-5,8-18H2,1H3
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 158n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099440
PNG
(CHEMBL3342856)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCNCC3)O2)CC1
Show InChI InChI=1S/C16H13FN2O3/c1-21-13-7-10-12(8-14(13)22-2)18-15(19-16(10)20)9-5-3-4-6-11(9)17/h3-8H,1-2H3,(H,18,19,20)
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 158n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099557
PNG
(CHEMBL3342875)
Show SMILES CCCCNC(=O)N1CCC2(CC1)OCC(CN1CCN(CC1)c1ccccc1OC)O2
Show InChI InChI=1S/C37H50N2O10/c1-7-38-17-34(18-49-32(42)20-10-8-9-11-23(20)39-26(40)14-19(2)31(39)41)13-12-25(46-4)36-22-15-21-24(45-3)16-35(43,27(22)28(21)47-5)37(44,33(36)38)30(48-6)29(34)36/h8-11,19,21-22,24-25,27-30,33,43-44H,7,12-18H2,1-6H3/t19-,21?,22+,24-,25-,27+,28-,29+,30-,33?,34?,35+,36?,37?/m0/s1
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 240n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099439
PNG
(CHEMBL3342855)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCS(=O)(=O)CC3)O2)CC1
Show InChI InChI=1S/C18H12N2O/c21-18-15-7-3-4-8-16(15)19-17(20-18)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H,19,20,21)
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 288n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50099455
PNG
(CHEMBL3342865)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)C(F)(F)F)O2)CC1
Show InChI InChI=1S/C14H7N3O4/c18-11-7-4-2-1-3-6(7)9-10(11)17-5-8(14(20)21)15-12(17)13(19)16-9/h1-5H,(H,16,19)(H,20,21)
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 324n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099436
PNG
(CHEMBL3341769)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCOCC3)O2)CC1
Show InChI InChI=1S/C19H28N2O4/c1-22-18-5-3-2-4-17(18)21-10-8-20(9-11-21)14-16-15-24-19(25-16)6-12-23-13-7-19/h2-5,16H,6-15H2,1H3
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 324n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099472
PNG
(CHEMBL3342873)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(C)(=O)=O)O2)CC1
Show InChI InChI=1S/C20H31N3O5S/c1-26-19-6-4-3-5-18(19)22-13-11-21(12-14-22)15-17-16-27-20(28-17)7-9-23(10-8-20)29(2,24)25/h3-6,17H,7-16H2,1-2H3
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 363n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099455
PNG
(CHEMBL3342865)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)C(F)(F)F)O2)CC1
Show InChI InChI=1S/C14H7N3O4/c18-11-7-4-2-1-3-6(7)9-10(11)17-5-8(14(20)21)15-12(17)13(19)16-9/h1-5H,(H,16,19)(H,20,21)
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 417n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099438
PNG
(CHEMBL3342854)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CC[S+]([O-])CC3)O2)CC1
Show InChI InChI=1S/C19H28N2O4S/c1-23-18-5-3-2-4-17(18)21-10-8-20(9-11-21)14-16-15-24-19(25-16)6-12-26(22)13-7-19/h2-5,16H,6-15H2,1H3
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 479n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099454
PNG
(CHEMBL3342864)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(C)=O)O2)CC1
Show InChI InChI=1S/C21H31N3O4/c1-17(25)23-9-7-21(8-10-23)27-16-18(28-21)15-22-11-13-24(14-12-22)19-5-3-4-6-20(19)26-2/h3-6,18H,7-16H2,1-2H3
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 1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))		BDBM50099455
PNG
(CHEMBL3342865)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)C(F)(F)F)O2)CC1
Show InChI InChI=1S/C14H7N3O4/c18-11-7-4-2-1-3-6(7)9-10(11)17-5-8(14(20)21)15-12(17)13(19)16-9/h1-5H,(H,16,19)(H,20,21)
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<1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))		BDBM50099434
PNG
(CHEMBL2234448)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCCCC3)O2)CC1
Show InChI InChI=1S/C20H30N2O3/c1-23-19-8-4-3-7-18(19)22-13-11-21(12-14-22)15-17-16-24-20(25-17)9-5-2-6-10-20/h3-4,7-8,17H,2,5-6,9-16H2,1H3
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<1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099455
PNG
(CHEMBL3342865)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)C(=O)C(F)(F)F)O2)CC1
Show InChI InChI=1S/C14H7N3O4/c18-11-7-4-2-1-3-6(7)9-10(11)17-5-8(14(20)21)15-12(17)13(19)16-9/h1-5H,(H,16,19)(H,20,21)
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 1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Homo sapiens (Human))		BDBM50099442
PNG
(CHEMBL3342858)
Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)c3ccccn3)O2)CC1
Show InChI InChI=1S/C14H9FN2O/c15-10-5-3-4-9(8-10)13-16-12-7-2-1-6-11(12)14(18)17-13/h1-8H,(H,16,17,18)
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 1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting

Eur J Med Chem 87: 248-66 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%