Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50127140 ((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 3.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035880 (CHEMBL1437990) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035856 (CHEMBL1345545) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.39E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035855 (CHEMBL1505015) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.29E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035860 (CHEMBL3361009) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.37E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035872 (CHEMBL3361019) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035857 (CHEMBL1451460) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035863 (CHEMBL3361012) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035864 (CHEMBL3361013) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035876 (CHEMBL3361023) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035878 (CHEMBL3361025) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035873 (CHEMBL3361020) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035867 (CHEMBL3352903) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035868 (CHEMBL579923 | GNF-Pf-4873 | SJ000233075 | TCMDC-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035870 (CHEMBL3361017) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035874 (CHEMBL3361021) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035858 (CHEMBL3361008) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035861 (CHEMBL3361010) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035871 (CHEMBL3361018) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035875 (CHEMBL3361022) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035877 (CHEMBL3361024) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035869 (CHEMBL3361016) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035866 (CHEMBL3361015) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035859 (CHEMBL1597544) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035879 (CHEMBL3361026) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035862 (CHEMBL3361011) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50035865 (CHEMBL3361014) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry | Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK | |||||||||||
More data for this Ligand-Target Pair |