Affinity Data by PubMed id=25453818

PubMed code 25453818

Found 21 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50059863 ((Z)-2-Methyl-3-tetradecyl-but-2-enedioic acid \| CH...) Show SMILES CCCCCCCCCCCCCC\C(C(O)=O)=C(/C)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50036274 (CHEMBL3361086) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50036270 (CHEMBL3361094) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50035931 (CHEMBL3361085) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50036277 (CHEMBL3361077) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50036276 (CHEMBL3361076) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50036272 (CHEMBL3361092) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50035927 (CHEMBL3361080) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50035929 (CHEMBL3361082) Show SMILES O=C(OCC#C)c1cc(C(=O)c2ccccc2)n2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50035921 (CHEMBL3361071) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50035926 (CHEMBL3361079) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50035928 (CHEMBL3361081) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50035923 (CHEMBL3361068) Show SMILES OC(=O)c1cc(C(=O)c2ccc(Br)cc2)n2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50035925 (CHEMBL3361066) Show SMILES OC(=O)c1cc(C(=O)c2ccccc2)n2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50035924 (CHEMBL3361067) Show SMILES OC(=O)c1cc(C(=O)c2ccc(Cl)cc2)n2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50036273 (CHEMBL3361093) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50035930 (CHEMBL3361084) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50036275 (CHEMBL3361075) Show SMILES O=C(NCC#C)c1cc(C(=O)c2ccccc2)n2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50035922 (CHEMBL3361070) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50036278 (CHEMBL3361078) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50036271 (CHEMBL3361072) Show SMILES Cc1ccn2c(cc(C(O)=O)c2c1)C(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
Alexandru Ioan Cuza University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%