Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50000780 (2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 0.890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards kappa opioid receptor using [3H](-)-U-69,593 in guinea pig ileum | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50000780 (2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description In vitro inhibition of rat liver dihydrofolate reductase. | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50017214 ((-)2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description In vitro inhibition of dihydrofolate reductase of Escherichia coli | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 109 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description In vitro inhibition of rat liver dihydrofolate reductase. | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50008848 ((+)2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 118 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards sigma opioid receptor using [3H]DTG in guinea pig ileum | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50017214 ((-)2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidi...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 167 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards kappa opioid receptor using [3H](-)-U-69,593 in guinea pig ileum | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50008848 ((+)2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 221 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description In vitro inhibition of dihydrofolate reductase of Escherichia coli | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50017214 ((-)2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards sigma opioid receptor using [3H]DTG in guinea pig ileum | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 299 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description In vitro inhibition of rat liver dihydrofolate reductase. | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50000780 (2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 594 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards sigma opioid receptor using [3H](+)-3-PPP in guinea pig ileum | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 874 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards sigma opioid receptor using [3H](+)-3-PPP in guinea pig ileum | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 874 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description In vitro inhibition of Escherichia coli dihydrofolate reductase. | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards kappa opioid receptor using [3H]-BREM in guinea pig ileum | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50008848 ((+)2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidi...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 2.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards kappa opioid receptor using [3H](-)-U-69,593 in guinea pig ileum | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50017214 ((-)2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 3.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards Dopamine receptor D2 using [3H]SULP in rat | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50008848 ((+)2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Digestive Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards Dopamine receptor D2 using [3H]SULP in rat | J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP | |||||||||||
More data for this Ligand-Target Pair |