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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM163719 (3-Cyclohexyl-5-{4-[4-(2-methoxyphenyl)piperazin-1-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | Article PubMed | 5 | -47.4 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM163721 (3-Cyclohexyl-5-{4-[4-(2,3-dichlorophenyl)piperazin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5 | -47.4 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM163720 (3-Cyclohexyl-5-{4-[4-(2-(methylthio)phenyl)piperaz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6 | -46.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM163713 (5-{4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl}-3-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 9 | -45.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM163720 (3-Cyclohexyl-5-{4-[4-(2-(methylthio)phenyl)piperaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 14 | -44.8 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM163717 (5-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl}-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 16 | -44.5 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM163714 (5-{4-[4-(2-(Methylthio)phenyl)piperazin-1-yl]butyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 17 | -44.3 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM22869 (6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 18 | -44.2 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM163719 (3-Cyclohexyl-5-{4-[4-(2-methoxyphenyl)piperazin-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 20 | -43.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM163713 (5-{4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl}-3-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 27 | -43.2 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM163714 (5-{4-[4-(2-(Methylthio)phenyl)piperazin-1-yl]butyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 28 | -43.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM163721 (3-Cyclohexyl-5-{4-[4-(2,3-dichlorophenyl)piperazin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 32 | -42.8 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM163718 (3-(2-Chlorophenyl)-5-{4-[4-(2-fluorophenyl)piperaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 37 | -42.4 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM163717 (5-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl}-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 70 | -40.8 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM163716 (5-{4-[4-(4-Chlorophenyl)piperazin-1-yl]butyl}-3-ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 79 | -40.5 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM163712 (3-Phenyl-5-[4-(4-phenylpiperazin-1-yl)butyl]-4,5-d...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 79 | -40.5 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM163718 (3-(2-Chlorophenyl)-5-{4-[4-(2-fluorophenyl)piperaz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 91 | -40.2 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM163712 (3-Phenyl-5-[4-(4-phenylpiperazin-1-yl)butyl]-4,5-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 95 | -40.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM163715 (5-{4-[4-(2-Fluorophenyl)piperazin-1-yl]butyl}-3-ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 100 | -40.0 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM163715 (5-{4-[4-(2-Fluorophenyl)piperazin-1-yl]butyl}-3-ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 119 | -39.5 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM22869 (6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 143 | -39.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM163716 (5-{4-[4-(4-Chlorophenyl)piperazin-1-yl]butyl}-3-ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 698 | -35.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Jagiellonian University Medical College | Assay Description All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room... | Chem Biol Drug Des 86: 697-703 (2015) Article DOI: 10.1111/cbdd.12539 BindingDB Entry DOI: 10.7270/Q2DR2T86 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
