Affinity Data by PubMed id=25699147

PubMed code 25699147

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Type-1 angiotensin II receptor A (RAT)	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-Ang II from AT1 receptor in rat liver membranes after 2 hrs by gamma-counting method				ACS Med Chem Lett 6: 178-82 (2015) Article DOI: 10.1021/ml500427r BindingDB Entry DOI: 10.7270/Q2HD7X98
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A (RAT)	BDBM50030814 (CHEMBL2086892) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-Ang II from AT1 receptor in rat liver membranes after 2 hrs by gamma-counting method				ACS Med Chem Lett 6: 178-82 (2015) Article DOI: 10.1021/ml500427r BindingDB Entry DOI: 10.7270/Q2HD7X98
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50141059 (CHEMBL289614 \| L-162782 \| N-Butyloxycarbonyl-4'-(2...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity to AT2 receptor (unknown origin)				ACS Med Chem Lett 6: 178-82 (2015) Article DOI: 10.1021/ml500427r BindingDB Entry DOI: 10.7270/Q2HD7X98
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50049195 (3-[(2'-(butylsulfonylcarbamate)-3'-propyl-1,1'-bip...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-[Sar1,Leu8]angiotensin II from human AT1 receptor expressed in african green monkey COS7 cells				ACS Med Chem Lett 6: 178-82 (2015) Article DOI: 10.1021/ml500427r BindingDB Entry DOI: 10.7270/Q2HD7X98
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50141059 (CHEMBL289614 \| L-162782 \| N-Butyloxycarbonyl-4'-(2...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-[Sar1,Leu8]angiotensin II from human AT1 receptor expressed in african green monkey COS7 cells				ACS Med Chem Lett 6: 178-82 (2015) Article DOI: 10.1021/ml500427r BindingDB Entry DOI: 10.7270/Q2HD7X98
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50049195 (3-[(2'-(butylsulfonylcarbamate)-3'-propyl-1,1'-bip...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity to AT2 receptor (unknown origin)				ACS Med Chem Lett 6: 178-82 (2015) Article DOI: 10.1021/ml500427r BindingDB Entry DOI: 10.7270/Q2HD7X98
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%