BindingDB logo
myBDB logout

PubMed code 26022843

Compile data set for download or QSAR
Found 39 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094910
PNG
(CHEMBL3589475)
Show SMILES COc1ccc(cc1)C(=C/c1ccncc1)\C(=O)N1CC(=O)Nc2ccccc12
Show InChI InChI=1S/C23H19N3O3/c1-29-18-8-6-17(7-9-18)19(14-16-10-12-24-13-11-16)23(28)26-15-22(27)25-20-4-2-3-5-21(20)26/h2-14H,15H2,1H3,(H,25,27)/b19-14+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094913
PNG
(CHEMBL3589482)
Show SMILES Oc1cc(cc(c1)-c1ccccc1)C(=O)N1CC(=O)Nc2ccccc12
Show InChI InChI=1S/C21H16N2O3/c24-17-11-15(14-6-2-1-3-7-14)10-16(12-17)21(26)23-13-20(25)22-18-8-4-5-9-19(18)23/h1-12,24H,13H2,(H,22,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094887
PNG
(CHEMBL3589478)
Show SMILES CC(=O)Nc1cccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccccc2)c1
Show InChI InChI=1S/C25H21N3O3/c1-17(29)26-20-11-7-8-18(14-20)15-21(19-9-3-2-4-10-19)25(31)28-16-24(30)27-22-12-5-6-13-23(22)28/h2-15H,16H2,1H3,(H,26,29)(H,27,30)/b21-15+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094896
PNG
(CHEMBL3589487)
Show SMILES O=C(N1CC(=O)Nc2ccccc12)c1cncc(c1)-c1cccc(c1)C#N
Show InChI InChI=1S/C14H10N2O2/c15-7-1-3-9-11(5-7)14(18)10-4-2-8(16)6-12(10)13(9)17/h1-6H,15-16H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094888
PNG
(CHEMBL3589479)
Show SMILES COc1ccc(\C=C(\C(=O)Nc2c(C)noc2C)c2ccc(OC)cc2)cc1
Show InChI InChI=1S/C22H22N2O4/c1-14-21(15(2)28-24-14)23-22(25)20(17-7-11-19(27-4)12-8-17)13-16-5-9-18(26-3)10-6-16/h5-13H,1-4H3,(H,23,25)/b20-13+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094898
PNG
(CHEMBL3589470)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccc(NC(C)=O)cc2)cc1
Show InChI InChI=1S/C14H10N2O4/c15-5-1-3-7(17)11-9(5)13(19)10-6(16)2-4-8(18)12(10)14(11)20/h1-4,17-18H,15-16H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094899
PNG
(CHEMBL3589471)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3cc(OC)ccc23)c2ccc(OC)cc2)cc1
Show InChI InChI=1S/C14H11N3O2/c15-7-3-1-2-6-10(7)14(19)12-9(17)5-4-8(16)11(12)13(6)18/h1-5H,15-17H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094899
PNG
(CHEMBL3589471)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3cc(OC)ccc23)c2ccc(OC)cc2)cc1
Show InChI InChI=1S/C14H11N3O2/c15-7-3-1-2-6-10(7)14(19)12-9(17)5-4-8(16)11(12)13(6)18/h1-5H,15-17H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094897
PNG
(CHEMBL3589469)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2cccs2)cc1
Show InChI InChI=1S/C14H12N4O2/c15-5-1-2-6(16)10-9(5)13(19)11-7(17)3-4-8(18)12(11)14(10)20/h1-4H,15-18H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094908
PNG
(CHEMBL3589473)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccc(OC)cc2)cc1
Show InChI InChI=1S/C25H22N2O4/c1-30-19-11-7-17(8-12-19)15-21(18-9-13-20(31-2)14-10-18)25(29)27-16-24(28)26-22-5-3-4-6-23(22)27/h3-15H,16H2,1-2H3,(H,26,28)/b21-15+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094914
PNG
(CHEMBL3589483)
Show SMILES COc1cc(cc(c1)-c1ccccc1)C(=O)N1CC(=O)Nc2ccccc12
Show InChI InChI=1S/C22H18N2O3/c1-27-18-12-16(15-7-3-2-4-8-15)11-17(13-18)22(26)24-14-21(25)23-19-9-5-6-10-20(19)24/h2-13H,14H2,1H3,(H,23,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094900
PNG
(CHEMBL3589472)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccc(C)c(C)c2)cc1
Show InChI InChI=1S/C14H9NO2/c15-8-5-6-11-12(7-8)14(17)10-4-2-1-3-9(10)13(11)16/h1-7H,15H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094908
PNG
(CHEMBL3589473)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccc(OC)cc2)cc1
Show InChI InChI=1S/C25H22N2O4/c1-30-19-11-7-17(8-12-19)15-21(18-9-13-20(31-2)14-10-18)25(29)27-16-24(28)26-22-5-3-4-6-23(22)27/h3-15H,16H2,1-2H3,(H,26,28)/b21-15+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094909
PNG
(CHEMBL3589474)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccc(OC)c(OC)c2)cc1
Show InChI InChI=1S/C26H24N2O5/c1-31-19-11-8-17(9-12-19)14-20(18-10-13-23(32-2)24(15-18)33-3)26(30)28-16-25(29)27-21-6-4-5-7-22(21)28/h4-15H,16H2,1-3H3,(H,27,29)/b20-14+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094894
PNG
(CHEMBL3589485)
Show SMILES O=C(N1CC(=O)Nc2ccccc12)c1cncc(c1)-c1ccccc1
Show InChI InChI=1S/C14H10N2O2/c15-10-6-5-9-11(12(10)16)14(18)8-4-2-1-3-7(8)13(9)17/h1-6H,15-16H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094886
PNG
(CHEMBL3589468)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccccc2)cc1
Show InChI InChI=1S/C24H20N2O3/c1-29-19-13-11-17(12-14-19)15-20(18-7-3-2-4-8-18)24(28)26-16-23(27)25-21-9-5-6-10-22(21)26/h2-15H,16H2,1H3,(H,25,27)/b20-15+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Similars
Article
PubMed
n/an/a 2.20E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094897
PNG
(CHEMBL3589469)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2cccs2)cc1
Show InChI InChI=1S/C14H12N4O2/c15-5-1-2-6(16)10-9(5)13(19)11-7(17)3-4-8(18)12(11)14(10)20/h1-4H,15-18H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094898
PNG
(CHEMBL3589470)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccc(NC(C)=O)cc2)cc1
Show InChI InChI=1S/C14H10N2O4/c15-5-1-3-7(17)11-9(5)13(19)10-6(16)2-4-8(18)12(10)14(11)20/h1-4,17-18H,15-16H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.40E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094915
PNG
(CHEMBL3589484)
Show SMILES COc1cccc(c1)-c1cncc(c1)C(=O)N1CC(=O)Nc2ccccc12
Show InChI InChI=1S/C21H17N3O3/c1-27-17-6-4-5-14(10-17)15-9-16(12-22-11-15)21(26)24-13-20(25)23-18-7-2-3-8-19(18)24/h2-12H,13H2,1H3,(H,23,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094910
PNG
(CHEMBL3589475)
Show SMILES COc1ccc(cc1)C(=C/c1ccncc1)\C(=O)N1CC(=O)Nc2ccccc12
Show InChI InChI=1S/C23H19N3O3/c1-29-18-8-6-17(7-9-18)19(14-16-10-12-24-13-11-16)23(28)26-15-22(27)25-20-4-2-3-5-21(20)26/h2-14H,15H2,1H3,(H,25,27)/b19-14+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094911
PNG
(CHEMBL3589476)
Show SMILES COC(=O)c1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccccc2)cc1
Show InChI InChI=1S/C25H20N2O4/c1-31-25(30)19-13-11-17(12-14-19)15-20(18-7-3-2-4-8-18)24(29)27-16-23(28)26-21-9-5-6-10-22(21)27/h2-15H,16H2,1H3,(H,26,28)/b20-15+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094911
PNG
(CHEMBL3589476)
Show SMILES COC(=O)c1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccccc2)cc1
Show InChI InChI=1S/C25H20N2O4/c1-31-25(30)19-13-11-17(12-14-19)15-20(18-7-3-2-4-8-18)24(29)27-16-23(28)26-21-9-5-6-10-22(21)27/h2-15H,16H2,1H3,(H,26,28)/b20-15+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094894
PNG
(CHEMBL3589485)
Show SMILES O=C(N1CC(=O)Nc2ccccc12)c1cncc(c1)-c1ccccc1
Show InChI InChI=1S/C14H10N2O2/c15-10-6-5-9-11(12(10)16)14(18)8-4-2-1-3-7(8)13(9)17/h1-6H,15-16H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 2.60E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094886
PNG
(CHEMBL3589468)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccccc2)cc1
Show InChI InChI=1S/C24H20N2O3/c1-29-19-13-11-17(12-14-19)15-20(18-7-3-2-4-8-18)24(28)26-16-23(27)25-21-9-5-6-10-22(21)26/h2-15H,16H2,1H3,(H,25,27)/b20-15+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Similars
PDB
Article
PubMed
n/an/a 2.60E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094909
PNG
(CHEMBL3589474)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccc(OC)c(OC)c2)cc1
Show InChI InChI=1S/C26H24N2O5/c1-31-19-11-8-17(9-12-19)14-20(18-10-13-23(32-2)24(15-18)33-3)26(30)28-16-25(29)27-21-6-4-5-7-22(21)28/h4-15H,16H2,1-3H3,(H,27,29)/b20-14+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.60E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094916
PNG
(CHEMBL3589486)
Show SMILES Oc1cccc(c1)-c1cncc(c1)C(=O)N1CC(=O)Nc2ccccc12
Show InChI InChI=1S/C20H15N3O3/c24-16-5-3-4-13(9-16)14-8-15(11-21-10-14)20(26)23-12-19(25)22-17-6-1-2-7-18(17)23/h1-11,24H,12H2,(H,22,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.90E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094912
PNG
(CHEMBL3589477)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3cc(OC)ccc23)c2ccccc2)cc1
Show InChI InChI=1S/C25H22N2O4/c1-30-19-10-8-17(9-11-19)14-21(18-6-4-3-5-7-18)25(29)27-16-24(28)26-22-15-20(31-2)12-13-23(22)27/h3-15H,16H2,1-2H3,(H,26,28)/b21-14+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.40E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094887
PNG
(CHEMBL3589478)
Show SMILES CC(=O)Nc1cccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccccc2)c1
Show InChI InChI=1S/C25H21N3O3/c1-17(29)26-20-11-7-8-18(14-20)15-21(19-9-3-2-4-10-19)25(31)28-16-24(30)27-22-12-5-6-13-23(22)28/h2-15H,16H2,1H3,(H,26,29)(H,27,30)/b21-15+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.00E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094888
PNG
(CHEMBL3589479)
Show SMILES COc1ccc(\C=C(\C(=O)Nc2c(C)noc2C)c2ccc(OC)cc2)cc1
Show InChI InChI=1S/C22H22N2O4/c1-14-21(15(2)28-24-14)23-22(25)20(17-7-11-19(27-4)12-8-17)13-16-5-9-18(26-3)10-6-16/h5-13H,1-4H3,(H,23,25)/b20-13+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.40E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094896
PNG
(CHEMBL3589487)
Show SMILES O=C(N1CC(=O)Nc2ccccc12)c1cncc(c1)-c1cccc(c1)C#N
Show InChI InChI=1S/C14H10N2O2/c15-7-1-3-9-11(5-7)14(18)10-4-2-8(16)6-12(10)13(9)17/h1-6H,15-16H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 4.40E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094889
PNG
(CHEMBL3589480)
Show SMILES NC(=O)c1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccccc2)cc1
Show InChI InChI=1S/C24H19N3O3/c25-23(29)18-12-10-16(11-13-18)14-19(17-6-2-1-3-7-17)24(30)27-15-22(28)26-20-8-4-5-9-21(20)27/h1-14H,15H2,(H2,25,29)(H,26,28)/b19-14+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.60E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094917
PNG
(CHEMBL3589488)
Show SMILES Fc1ccc(cc1)-c1cncc(c1)C(=O)N1CC(=O)Nc2ccccc12
Show InChI InChI=1S/C20H14FN3O2/c21-16-7-5-13(6-8-16)14-9-15(11-22-10-14)20(26)24-12-19(25)23-17-3-1-2-4-18(17)24/h1-11H,12H2,(H,23,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.70E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094889
PNG
(CHEMBL3589480)
Show SMILES NC(=O)c1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccccc2)cc1
Show InChI InChI=1S/C24H19N3O3/c25-23(29)18-12-10-16(11-13-18)14-19(17-6-2-1-3-7-17)24(30)27-15-22(28)26-20-8-4-5-9-21(20)27/h1-14H,15H2,(H2,25,29)(H,26,28)/b19-14+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.90E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094918
PNG
(CHEMBL3589489)
Show SMILES Clc1ccc(cc1)-c1cncc(c1)C(=O)N1CC(=O)Nc2ccccc12
Show InChI InChI=1S/C20H14ClN3O2/c21-16-7-5-13(6-8-16)14-9-15(11-22-10-14)20(26)24-12-19(25)23-17-3-1-2-4-18(17)24/h1-11H,12H2,(H,23,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.90E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094919
PNG
(CHEMBL3589490)
Show SMILES COc1cc(NCc2ccccc2)cc(c1)C(=O)N1CC(=O)Nc2ccccc12
Show InChI InChI=1S/C23H21N3O3/c1-29-19-12-17(11-18(13-19)24-14-16-7-3-2-4-8-16)23(28)26-15-22(27)25-20-9-5-6-10-21(20)26/h2-13,24H,14-15H2,1H3,(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094890
PNG
(CHEMBL3589481)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccc(OC)cc2OC)cc1
Show InChI InChI=1S/C14H10N2O2/c15-9-5-1-3-7-11(9)14(18)8-4-2-6-10(16)12(8)13(7)17/h1-6H,15-16H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094900
PNG
(CHEMBL3589472)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccc(C)c(C)c2)cc1
Show InChI InChI=1S/C14H9NO2/c15-8-5-6-11-12(7-8)14(17)10-4-2-1-3-9(10)13(11)16/h1-7H,15H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50094890
PNG
(CHEMBL3589481)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3ccccc23)c2ccc(OC)cc2OC)cc1
Show InChI InChI=1S/C14H10N2O2/c15-9-5-1-3-7-11(9)14(18)8-4-2-6-10(16)12(8)13(7)17/h1-6H,15-16H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD4(1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
Bromodomain-containing protein 2


(Homo sapiens (Human))		BDBM50094912
PNG
(CHEMBL3589477)
Show SMILES COc1ccc(\C=C(\C(=O)N2CC(=O)Nc3cc(OC)ccc23)c2ccccc2)cc1
Show InChI InChI=1S/C25H22N2O4/c1-30-19-10-8-17(9-11-19)14-21(18-6-4-3-5-7-18)25(29)27-16-24(28)26-22-15-20(31-2)12-13-23(22)27/h3-15H,16H2,1-2H3,(H,26,28)/b21-14+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Inhibition of HTRF binding to N-terminal His-tagged BRD2(2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide and Cryptate-labe...

Bioorg Med Chem Lett 25: 2818-23 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.107
BindingDB Entry DOI: 10.7270/Q25M67FC
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%