Affinity Data by PubMed id=26190460

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Endothelin-1 receptor (RAT)	BDBM50108104 (CHEMBL3601500) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Kansas State University Curated by ChEMBL					Assay Description Antagonist activity at endothelin A receptor in rat A7r5 cells assessed as inhibition of ET-1-induced increase in cytosolic free Ca2+ level treated 1...				Bioorg Med Chem 23: 5985-98 (2015) Article DOI: 10.1016/j.bmc.2015.06.055 BindingDB Entry DOI: 10.7270/Q2862J7P
Kansas State University Curated by ChEMBL					More data for this Ligand-Target Pair
Endothelin-1 receptor (RAT)	BDBM50108104 (CHEMBL3601500) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Kansas State University Curated by ChEMBL					Assay Description Antagonist activity at endothelin A receptor in Wistar rat thoracic aorta strips assessed as inhibition of ET1-induced vasoconstriction preincubated ...				Bioorg Med Chem 23: 5985-98 (2015) Article DOI: 10.1016/j.bmc.2015.06.055 BindingDB Entry DOI: 10.7270/Q2862J7P
Kansas State University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%