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PubMed code 26218264

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Baculoviral IAP repeat-containing protein 2


(Homo sapiens (Human))		BDBM156012
PNG
(US9018214, 63)
Show SMILES COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3ccccc3)cc12 |r|
Show InChI InChI=1S/C25H34N4O2/c1-18-14-28(21(12-26-18)16-31-4)15-24(30)29-17-25(2,3)22-13-27-20(11-23(22)29)10-19-8-6-5-7-9-19/h5-9,11,13,18,21,26H,10,12,14-17H2,1-4H3/t18-,21-/m1/s1
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n/an/a 10n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at cIAP1-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM156012
PNG
(US9018214, 63)
Show SMILES COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3ccccc3)cc12 |r|
Show InChI InChI=1S/C25H34N4O2/c1-18-14-28(21(12-26-18)16-31-4)15-24(30)29-17-25(2,3)22-13-27-20(11-23(22)29)10-19-8-6-5-7-9-19/h5-9,11,13,18,21,26H,10,12,14-17H2,1-4H3/t18-,21-/m1/s1
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n/an/a 160n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2


(Homo sapiens (Human))		BDBM156011
PNG
(US9018214, 62)
Show SMILES COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cl)cc12 |r|
Show InChI InChI=1S/C18H27ClN4O2/c1-12-8-22(13(6-20-12)10-25-4)9-17(24)23-11-18(2,3)14-7-21-16(19)5-15(14)23/h5,7,12-13,20H,6,8-11H2,1-4H3/t12-,13-/m1/s1
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n/an/a 320n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at cIAP1-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM156011
PNG
(US9018214, 62)
Show SMILES COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cl)cc12 |r|
Show InChI InChI=1S/C18H27ClN4O2/c1-12-8-22(13(6-20-12)10-25-4)9-17(24)23-11-18(2,3)14-7-21-16(19)5-15(14)23/h5,7,12-13,20H,6,8-11H2,1-4H3/t12-,13-/m1/s1
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n/an/a 640n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2


(Homo sapiens (Human))		BDBM155993
PNG
(US9018214, 44)
Show SMILES COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2ccc(Cl)cc12 |r|
Show InChI InChI=1S/C19H28ClN3O2/c1-13-9-22(15(8-21-13)11-25-4)10-18(24)23-12-19(2,3)16-6-5-14(20)7-17(16)23/h5-7,13,15,21H,8-12H2,1-4H3/t13-,15-/m1/s1
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n/an/a 650n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at cIAP1-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM155993
PNG
(US9018214, 44)
Show SMILES COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2ccc(Cl)cc12 |r|
Show InChI InChI=1S/C19H28ClN3O2/c1-13-9-22(15(8-21-13)11-25-4)10-18(24)23-12-19(2,3)16-6-5-14(20)7-17(16)23/h5-7,13,15,21H,8-12H2,1-4H3/t13-,15-/m1/s1
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n/an/a 1.50E+3n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2


(Homo sapiens (Human))		BDBM155969
PNG
(US9018214, 20)
Show SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ccc(Cl)cc23)CCN1 |r|
Show InChI InChI=1S/C17H24ClN3O/c1-12-9-20(7-6-19-12)10-16(22)21-11-17(2,3)14-5-4-13(18)8-15(14)21/h4-5,8,12,19H,6-7,9-11H2,1-3H3/t12-/m1/s1
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n/an/a 3.70E+3n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at cIAP1-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM155979
PNG
(US9018214, 30)
Show SMILES C[C@@H]1CN(CC(=O)N2CCc3ccc(cc23)S(C)(=O)=O)CCN1 |r|
Show InChI InChI=1S/C16H23N3O3S/c1-12-10-18(8-6-17-12)11-16(20)19-7-5-13-3-4-14(9-15(13)19)23(2,21)22/h3-4,9,12,17H,5-8,10-11H2,1-2H3/t12-/m1/s1
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n/an/a 4.10E+3n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM155969
PNG
(US9018214, 20)
Show SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ccc(Cl)cc23)CCN1 |r|
Show InChI InChI=1S/C17H24ClN3O/c1-12-9-20(7-6-19-12)10-16(22)21-11-17(2,3)14-5-4-13(18)8-15(14)21/h4-5,8,12,19H,6-7,9-11H2,1-3H3/t12-/m1/s1
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n/an/a 5.50E+3n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM155971
PNG
(US9018214, 22)
Show SMILES C[C@@H]1CN(CC(=O)N2CCc3ccc(cc23)C(F)(F)F)CCN1 |r|
Show InChI InChI=1S/C16H20F3N3O/c1-11-9-21(7-5-20-11)10-15(23)22-6-4-12-2-3-13(8-14(12)22)16(17,18)19/h2-3,8,11,20H,4-7,9-10H2,1H3/t11-/m1/s1
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n/an/a 5.90E+3n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM155983
PNG
(US9018214, 34)
Show SMILES C[C@@H]1CN(CC(=O)N2CCc3cnc(Cl)cc23)CCN1 |r|
Show InChI InChI=1S/C14H19ClN4O/c1-10-8-18(5-3-16-10)9-14(20)19-4-2-11-7-17-13(15)6-12(11)19/h6-7,10,16H,2-5,8-9H2,1H3/t10-/m1/s1
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n/an/a 7.70E+3n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM155950
PNG
(US9018214, 1)
Show SMILES C[C@@H]1CN(CC(=O)N2CCc3ccc(Br)cc23)CCN1 |r|
Show InChI InChI=1S/C15H20BrN3O/c1-11-9-18(7-5-17-11)10-15(20)19-6-4-12-2-3-13(16)8-14(12)19/h2-3,8,11,17H,4-7,9-10H2,1H3/t11-/m1/s1
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n/an/a 9.80E+3n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM155953
PNG
(US9018214, 4)
Show SMILES C[C@@H]1CN(CC(=O)N2CCc3ccc(Cl)cc23)CCN1 |r|
Show InChI InChI=1S/C15H20ClN3O/c1-11-9-18(7-5-17-11)10-15(20)19-6-4-12-2-3-13(16)8-14(12)19/h2-3,8,11,17H,4-7,9-10H2,1H3/t11-/m1/s1
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n/an/a 1.30E+4n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2


(Homo sapiens (Human))		BDBM155983
PNG
(US9018214, 34)
Show SMILES C[C@@H]1CN(CC(=O)N2CCc3cnc(Cl)cc23)CCN1 |r|
Show InChI InChI=1S/C14H19ClN4O/c1-10-8-18(5-3-16-10)9-14(20)19-4-2-11-7-17-13(15)6-12(11)19/h6-7,10,16H,2-5,8-9H2,1H3/t10-/m1/s1
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n/an/a 2.00E+4n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at cIAP1-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2


(Homo sapiens (Human))		BDBM50109042
PNG
(CHEMBL181785)
Show SMILES CC(C)[C@H](NC(=O)[C@H](C)N)C(N)=O
Show InChI InChI=1S/C8H17N3O2/c1-4(2)6(7(10)12)11-8(13)5(3)9/h4-6H,9H2,1-3H3,(H2,10,12)(H,11,13)/t5-,6-/m0/s1
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n/an/a 2.40E+4n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at cIAP1-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2


(Homo sapiens (Human))		BDBM50109043
PNG
(CHEMBL3600720)
Show SMILES C[C@H](N)C(=O)Nc1cccc(N)n1 |r|
Show InChI InChI=1S/C8H12N4O/c1-5(9)8(13)12-7-4-2-3-6(10)11-7/h2-5H,9H2,1H3,(H3,10,11,12,13)/t5-/m0/s1
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n/an/a 2.70E+4n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at cIAP1-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM155955
PNG
(US9018214, 6)
Show SMILES C[C@@H]1CN(CC(=O)N2CCc3ccc(C)cc23)CCN1 |r|
Show InChI InChI=1S/C16H23N3O/c1-12-3-4-14-5-7-19(15(14)9-12)16(20)11-18-8-6-17-13(2)10-18/h3-4,9,13,17H,5-8,10-11H2,1-2H3/t13-/m1/s1
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n/an/a 4.60E+4n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM155959
PNG
(US9018214, 10)
Show SMILES C[C@@H]1CN(CC(=O)N2CCc3ccc(F)cc23)CCN1 |r|
Show InChI InChI=1S/C15H20FN3O/c1-11-9-18(7-5-17-11)10-15(20)19-6-4-12-2-3-13(16)8-14(12)19/h2-3,8,11,17H,4-7,9-10H2,1H3/t11-/m1/s1
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n/an/a 5.10E+4n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM155962
PNG
(US9018214, 13)
Show SMILES CC(C)c1ccc2CCN(C(=O)CN3CCN[C@H](C)C3)c2c1 |r|
Show InChI InChI=1S/C18H27N3O/c1-13(2)16-5-4-15-6-8-21(17(15)10-16)18(22)12-20-9-7-19-14(3)11-20/h4-5,10,13-14,19H,6-9,11-12H2,1-3H3/t14-/m1/s1
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n/an/a 5.90E+4n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM50109043
PNG
(CHEMBL3600720)
Show SMILES C[C@H](N)C(=O)Nc1cccc(N)n1 |r|
Show InChI InChI=1S/C8H12N4O/c1-5(9)8(13)12-7-4-2-3-6(10)11-7/h2-5H,9H2,1H3,(H3,10,11,12,13)/t5-/m0/s1
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n/an/a 1.10E+5n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2


(Homo sapiens (Human))		BDBM50109044
PNG
(CHEMBL3600721)
Show SMILES C[C@@H]1CN(CC(=O)N2CCCC2)CCN1 |r|
Show InChI InChI=1S/C11H21N3O/c1-10-8-13(7-4-12-10)9-11(15)14-5-2-3-6-14/h10,12H,2-9H2,1H3/t10-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

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antibodypedia
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UniChem

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n/an/a 4.10E+5n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at cIAP1-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM50109042
PNG
(CHEMBL181785)
Show SMILES CC(C)[C@H](NC(=O)[C@H](C)N)C(N)=O
Show InChI InChI=1S/C8H17N3O2/c1-4(2)6(7(10)12)11-8(13)5(3)9/h4-6H,9H2,1-3H3,(H2,10,12)(H,11,13)/t5-,6-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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DrugBank
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CHEMBL
KEGG
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UniChem

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n/an/a 1.20E+6n/an/an/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assay

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM50393505
PNG
(CHEMBL2158051)
Show SMILES CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)CC(C)C |r|
Show InChI InChI=1S/C32H43N5O4/c1-21(2)19-28(38)36-18-17-25-15-16-27(37(25)32(41)26(20-36)34-30(39)22(3)33-4)31(40)35-29(23-11-7-5-8-12-23)24-13-9-6-10-14-24/h5-14,21-22,25-27,29,33H,15-20H2,1-4H3,(H,34,39)(H,35,40)/t22-,25+,26-,27-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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antibodypedia
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MCE
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n/an/an/an/a 34n/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at full-length FLAG-tagged XIAP (unknown origin) transfected in HEK293 cells assessed as inhibition of interaction with caspase 9...

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM156012
PNG
(US9018214, 63)
Show SMILES COC[C@H]1CN[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(Cc3ccccc3)cc12 |r|
Show InChI InChI=1S/C25H34N4O2/c1-18-14-28(21(12-26-18)16-31-4)15-24(30)29-17-25(2,3)22-13-27-20(11-23(22)29)10-19-8-6-5-7-9-19/h5-9,11,13,18,21,26H,10,12,14-17H2,1-4H3/t18-,21-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 140n/an/an/an/a



Astex Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at full-length FLAG-tagged XIAP (unknown origin) transfected in HEK293 cells assessed as inhibition of interaction with caspase 9...

J Med Chem 58: 6574-88 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00706
BindingDB Entry DOI: 10.7270/Q2DR2X8F
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%