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PubMed code 26244990

Compile data set for download or QSAR
Found 78 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholinesterase


(Equus caballus (Horse))		BDBM50119275
PNG
(CHEMBL3617399)
Show SMILES [O-][N+](=O)c1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccc(I)cc2)n1
Show InChI InChI=1S/C18H11IN4O4S/c19-11-1-3-12(4-2-11)20-17(24)22-18-21-14(9-28-18)16-8-10-7-13(23(25)26)5-6-15(10)27-16/h1-9H,(H2,20,21,22,24)
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n/an/a 2.03E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119106
PNG
(CHEMBL3617394)
Show SMILES [O-][N+](=O)c1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccccc2)n1
Show InChI InChI=1S/C18H12N4O4S/c23-17(19-12-4-2-1-3-5-12)21-18-20-14(10-27-18)16-9-11-8-13(22(24)25)6-7-15(11)26-16/h1-10H,(H2,19,20,21,23)
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n/an/a 2.26E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM10404
PNG
((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Show SMILES COc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24 |r,c:12|
Show InChI InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1
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n/an/a 2.41E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119081
PNG
(CHEMBL3617385)
Show SMILES [O-][N+](=O)c1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)cc1
Show InChI InChI=1S/C18H11BrN4O4S/c19-11-1-6-15-10(7-11)8-16(27-15)14-9-28-18(21-14)22-17(24)20-12-2-4-13(5-3-12)23(25)26/h1-9H,(H2,20,21,22,24)
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n/an/a 3.12E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118820
PNG
(CHEMBL3617369)
Show SMILES [O-][N+](=O)c1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C18H12N4O4S/c23-17(19-12-5-7-13(8-6-12)22(24)25)21-18-20-14(10-27-18)16-9-11-3-1-2-4-15(11)26-16/h1-10H,(H2,19,20,21,23)
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n/an/a 3.44E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119098
PNG
(CHEMBL3617386)
Show SMILES Fc1ccccc1NC(=O)Nc1nc(cs1)-c1cc2cc(Br)ccc2o1
Show InChI InChI=1S/C18H11BrFN3O2S/c19-11-5-6-15-10(7-11)8-16(25-15)14-9-26-18(22-14)23-17(24)21-13-4-2-1-3-12(13)20/h1-9H,(H2,21,22,23,24)
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n/an/a 3.85E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119106
PNG
(CHEMBL3617394)
Show SMILES [O-][N+](=O)c1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccccc2)n1
Show InChI InChI=1S/C18H12N4O4S/c23-17(19-12-4-2-1-3-5-12)21-18-20-14(10-27-18)16-9-11-8-13(22(24)25)6-7-15(11)26-16/h1-10H,(H2,19,20,21,23)
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n/an/a 4.42E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119081
PNG
(CHEMBL3617385)
Show SMILES [O-][N+](=O)c1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)cc1
Show InChI InChI=1S/C18H11BrN4O4S/c19-11-1-6-15-10(7-11)8-16(27-15)14-9-28-18(21-14)22-17(24)20-12-2-4-13(5-3-12)23(25)26/h1-9H,(H2,20,21,22,24)
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n/an/a 4.78E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119072
PNG
(CHEMBL3617383)
Show SMILES [O-][N+](=O)c1ccccc1NC(=O)Nc1nc(cs1)-c1cc2cc(Br)ccc2o1
Show InChI InChI=1S/C18H11BrN4O4S/c19-11-5-6-15-10(7-11)8-16(27-15)13-9-28-18(21-13)22-17(24)20-12-3-1-2-4-14(12)23(25)26/h1-9H,(H2,20,21,22,24)
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n/an/a 5.12E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118820
PNG
(CHEMBL3617369)
Show SMILES [O-][N+](=O)c1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C18H12N4O4S/c23-17(19-12-5-7-13(8-6-12)22(24)25)21-18-20-14(10-27-18)16-9-11-3-1-2-4-15(11)26-16/h1-10H,(H2,19,20,21,23)
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n/an/a 5.23E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119275
PNG
(CHEMBL3617399)
Show SMILES [O-][N+](=O)c1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccc(I)cc2)n1
Show InChI InChI=1S/C18H11IN4O4S/c19-11-1-3-12(4-2-11)20-17(24)22-18-21-14(9-28-18)16-8-10-7-13(23(25)26)5-6-15(10)27-16/h1-9H,(H2,20,21,22,24)
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n/an/a 5.53E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118960
PNG
(CHEMBL3617381)
Show SMILES Cc1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)cc1
Show InChI InChI=1S/C19H14BrN3O2S/c1-11-2-5-14(6-3-11)21-18(24)23-19-22-15(10-26-19)17-9-12-8-13(20)4-7-16(12)25-17/h2-10H,1H3,(H2,21,22,23,24)
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n/an/a 5.65E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119104
PNG
(CHEMBL3617392)
Show SMILES Brc1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccc(I)cc2)n1
Show InChI InChI=1S/C18H11BrIN3O2S/c19-11-1-6-15-10(7-11)8-16(25-15)14-9-26-18(22-14)23-17(24)21-13-4-2-12(20)3-5-13/h1-9H,(H2,21,22,23,24)
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n/an/a 6.42E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118817
PNG
(CHEMBL3617372)
Show SMILES Fc1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C18H12FN3O2S/c19-12-5-7-13(8-6-12)20-17(23)22-18-21-14(10-25-18)16-9-11-3-1-2-4-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 7.45E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119101
PNG
(CHEMBL3617389)
Show SMILES Clc1cccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)c1
Show InChI InChI=1S/C18H11BrClN3O2S/c19-11-4-5-15-10(6-11)7-16(25-15)14-9-26-18(22-14)23-17(24)21-13-3-1-2-12(20)8-13/h1-9H,(H2,21,22,23,24)
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n/an/a 7.93E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119072
PNG
(CHEMBL3617383)
Show SMILES [O-][N+](=O)c1ccccc1NC(=O)Nc1nc(cs1)-c1cc2cc(Br)ccc2o1
Show InChI InChI=1S/C18H11BrN4O4S/c19-11-5-6-15-10(7-11)8-16(27-15)13-9-28-18(21-13)22-17(24)20-12-3-1-2-4-14(12)23(25)26/h1-9H,(H2,20,21,22,24)
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n/an/a 8.82E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119098
PNG
(CHEMBL3617386)
Show SMILES Fc1ccccc1NC(=O)Nc1nc(cs1)-c1cc2cc(Br)ccc2o1
Show InChI InChI=1S/C18H11BrFN3O2S/c19-11-5-6-15-10(7-11)8-16(25-15)14-9-26-18(22-14)23-17(24)21-13-4-2-1-3-12(13)20/h1-9H,(H2,21,22,23,24)
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n/an/a 9.25E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118816
PNG
(CHEMBL3617373)
Show SMILES Clc1cccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)c1
Show InChI InChI=1S/C18H12ClN3O2S/c19-12-5-3-6-13(9-12)20-17(23)22-18-21-14(10-25-18)16-8-11-4-1-2-7-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 9.67E+3n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118890
PNG
(CHEMBL3617365)
Show SMILES Cc1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C19H15N3O2S/c1-12-6-8-14(9-7-12)20-18(23)22-19-21-15(11-25-19)17-10-13-4-2-3-5-16(13)24-17/h2-11H,1H3,(H2,20,21,22,23)
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n/an/a 1.04E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119103
PNG
(CHEMBL3617391)
Show SMILES Brc1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)cc1
Show InChI InChI=1S/C18H11Br2N3O2S/c19-11-1-4-13(5-2-11)21-17(24)23-18-22-14(9-26-18)16-8-10-7-12(20)3-6-15(10)25-16/h1-9H,(H2,21,22,23,24)
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n/an/a 1.19E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118958
PNG
(CHEMBL3617379)
Show SMILES COc1cccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)c1
Show InChI InChI=1S/C19H14BrN3O3S/c1-25-14-4-2-3-13(9-14)21-18(24)23-19-22-15(10-27-19)17-8-11-7-12(20)5-6-16(11)26-17/h2-10H,1H3,(H2,21,22,23,24)
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n/an/a 1.40E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM10404
PNG
((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Show SMILES COc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24 |r,c:12|
Show InChI InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1
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n/an/a 1.74E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119075
PNG
(CHEMBL3617384)
Show SMILES [O-][N+](=O)c1cccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)c1
Show InChI InChI=1S/C18H11BrN4O4S/c19-11-4-5-15-10(6-11)7-16(27-15)14-9-28-18(21-14)22-17(24)20-12-2-1-3-13(8-12)23(25)26/h1-9H,(H2,20,21,22,24)
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n/an/a 1.75E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118818
PNG
(CHEMBL3617371)
Show SMILES Fc1cccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)c1
Show InChI InChI=1S/C18H12FN3O2S/c19-12-5-3-6-13(9-12)20-17(23)22-18-21-14(10-25-18)16-8-11-4-1-2-7-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 1.80E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118889
PNG
(CHEMBL3617366)
Show SMILES O=C(Nc1nc(cs1)-c1cc2ccccc2o1)Nc1ccccc1
Show InChI InChI=1S/C18H13N3O2S/c22-17(19-13-7-2-1-3-8-13)21-18-20-14(11-24-18)16-10-12-6-4-5-9-15(12)23-16/h1-11H,(H2,19,20,21,22)
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n/an/a 2.13E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118956
PNG
(CHEMBL3617377)
Show SMILES Ic1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C18H12IN3O2S/c19-12-5-7-13(8-6-12)20-17(23)22-18-21-14(10-25-18)16-9-11-3-1-2-4-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 2.14E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118816
PNG
(CHEMBL3617373)
Show SMILES Clc1cccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)c1
Show InChI InChI=1S/C18H12ClN3O2S/c19-12-5-3-6-13(9-12)20-17(23)22-18-21-14(10-25-18)16-8-11-4-1-2-7-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 2.15E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119102
PNG
(CHEMBL3617390)
Show SMILES Clc1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)cc1
Show InChI InChI=1S/C18H11BrClN3O2S/c19-11-1-6-15-10(7-11)8-16(25-15)14-9-26-18(22-14)23-17(24)21-13-4-2-12(20)3-5-13/h1-9H,(H2,21,22,23,24)
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n/an/a 2.22E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118963
PNG
(CHEMBL3617382)
Show SMILES Brc1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccccc2)n1
Show InChI InChI=1S/C18H12BrN3O2S/c19-12-6-7-15-11(8-12)9-16(24-15)14-10-25-18(21-14)22-17(23)20-13-4-2-1-3-5-13/h1-10H,(H2,20,21,22,23)
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n/an/a 2.34E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118889
PNG
(CHEMBL3617366)
Show SMILES O=C(Nc1nc(cs1)-c1cc2ccccc2o1)Nc1ccccc1
Show InChI InChI=1S/C18H13N3O2S/c22-17(19-13-7-2-1-3-8-13)21-18-20-14(11-24-18)16-10-12-6-4-5-9-15(12)23-16/h1-11H,(H2,19,20,21,22)
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n/an/a 2.47E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119107
PNG
(CHEMBL3617395)
Show SMILES [O-][N+](=O)c1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(ccc3o2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C18H11N5O6S/c24-17(19-11-1-3-12(4-2-11)22(25)26)21-18-20-14(9-30-18)16-8-10-7-13(23(27)28)5-6-15(10)29-16/h1-9H,(H2,19,20,21,24)
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n/an/a 2.52E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119107
PNG
(CHEMBL3617395)
Show SMILES [O-][N+](=O)c1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(ccc3o2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C18H11N5O6S/c24-17(19-11-1-3-12(4-2-11)22(25)26)21-18-20-14(9-30-18)16-8-10-7-13(23(27)28)5-6-15(10)29-16/h1-9H,(H2,19,20,21,24)
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n/an/a 2.56E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119101
PNG
(CHEMBL3617389)
Show SMILES Clc1cccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)c1
Show InChI InChI=1S/C18H11BrClN3O2S/c19-11-4-5-15-10(6-11)7-16(25-15)14-9-26-18(22-14)23-17(24)21-13-3-1-2-12(20)8-13/h1-9H,(H2,21,22,23,24)
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n/an/a 2.63E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119109
PNG
(CHEMBL3617397)
Show SMILES [O-][N+](=O)c1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccc(Cl)cc2)n1
Show InChI InChI=1S/C18H11ClN4O4S/c19-11-1-3-12(4-2-11)20-17(24)22-18-21-14(9-28-18)16-8-10-7-13(23(25)26)5-6-15(10)27-16/h1-9H,(H2,20,21,22,24)
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n/an/a 2.66E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118821
PNG
(CHEMBL3617368)
Show SMILES [O-][N+](=O)c1cccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)c1
Show InChI InChI=1S/C18H12N4O4S/c23-17(19-12-5-3-6-13(9-12)22(24)25)21-18-20-14(10-27-18)16-8-11-4-1-2-7-15(11)26-16/h1-10H,(H2,19,20,21,23)
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n/an/a 2.68E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119170
PNG
(CHEMBL3617398)
Show SMILES [O-][N+](=O)c1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccc(Br)cc2)n1
Show InChI InChI=1S/C18H11BrN4O4S/c19-11-1-3-12(4-2-11)20-17(24)22-18-21-14(9-28-18)16-8-10-7-13(23(25)26)5-6-15(10)27-16/h1-9H,(H2,20,21,22,24)
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n/an/a 2.82E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119099
PNG
(CHEMBL3617387)
Show SMILES Fc1cccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)c1
Show InChI InChI=1S/C18H11BrFN3O2S/c19-11-4-5-15-10(6-11)7-16(25-15)14-9-26-18(22-14)23-17(24)21-13-3-1-2-12(20)8-13/h1-9H,(H2,21,22,23,24)
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n/an/a 2.94E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118958
PNG
(CHEMBL3617379)
Show SMILES COc1cccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)c1
Show InChI InChI=1S/C19H14BrN3O3S/c1-25-14-4-2-3-13(9-14)21-18(24)23-19-22-15(10-27-19)17-8-11-7-12(20)5-6-16(11)26-17/h2-10H,1H3,(H2,21,22,23,24)
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n/an/a 2.94E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119109
PNG
(CHEMBL3617397)
Show SMILES [O-][N+](=O)c1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccc(Cl)cc2)n1
Show InChI InChI=1S/C18H11ClN4O4S/c19-11-1-3-12(4-2-11)20-17(24)22-18-21-14(9-28-18)16-8-10-7-13(23(25)26)5-6-15(10)27-16/h1-9H,(H2,20,21,22,24)
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n/an/a 3.06E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118819
PNG
(CHEMBL3617370)
Show SMILES Fc1ccccc1NC(=O)Nc1nc(cs1)-c1cc2ccccc2o1
Show InChI InChI=1S/C18H12FN3O2S/c19-12-6-2-3-7-13(12)20-17(23)22-18-21-14(10-25-18)16-9-11-5-1-4-8-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 3.09E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118959
PNG
(CHEMBL3617380)
Show SMILES COc1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)cc1
Show InChI InChI=1S/C19H14BrN3O3S/c1-25-14-5-3-13(4-6-14)21-18(24)23-19-22-15(10-27-19)17-9-11-8-12(20)2-7-16(11)26-17/h2-10H,1H3,(H2,21,22,23,24)
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n/an/a 3.10E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118960
PNG
(CHEMBL3617381)
Show SMILES Cc1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)cc1
Show InChI InChI=1S/C19H14BrN3O2S/c1-11-2-5-14(6-3-11)21-18(24)23-19-22-15(10-26-19)17-9-12-8-13(20)4-7-16(12)25-17/h2-10H,1H3,(H2,21,22,23,24)
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n/an/a 3.25E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118959
PNG
(CHEMBL3617380)
Show SMILES COc1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)cc1
Show InChI InChI=1S/C19H14BrN3O3S/c1-25-14-5-3-13(4-6-14)21-18(24)23-19-22-15(10-27-19)17-9-11-8-12(20)2-7-16(11)26-17/h2-10H,1H3,(H2,21,22,23,24)
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n/an/a 3.28E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118797
PNG
(CHEMBL3617376)
Show SMILES Brc1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C18H12BrN3O2S/c19-12-5-7-13(8-6-12)20-17(23)22-18-21-14(10-25-18)16-9-11-3-1-2-4-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 3.28E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119105
PNG
(CHEMBL3617393)
Show SMILES COc1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(ccc3o2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C19H14N4O5S/c1-27-14-5-2-12(3-6-14)20-18(24)22-19-21-15(10-29-19)17-9-11-8-13(23(25)26)4-7-16(11)28-17/h2-10H,1H3,(H2,20,21,22,24)
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n/an/a 3.41E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119170
PNG
(CHEMBL3617398)
Show SMILES [O-][N+](=O)c1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccc(Br)cc2)n1
Show InChI InChI=1S/C18H11BrN4O4S/c19-11-1-3-12(4-2-11)20-17(24)22-18-21-14(9-28-18)16-8-10-7-13(23(25)26)5-6-15(10)27-16/h1-9H,(H2,20,21,22,24)
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n/an/a 3.45E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118963
PNG
(CHEMBL3617382)
Show SMILES Brc1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccccc2)n1
Show InChI InChI=1S/C18H12BrN3O2S/c19-12-6-7-15-11(8-12)9-16(24-15)14-10-25-18(21-14)22-17(23)20-13-4-2-1-3-5-13/h1-10H,(H2,20,21,22,23)
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n/an/a 3.50E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119100
PNG
(CHEMBL3617388)
Show SMILES Fc1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)cc1
Show InChI InChI=1S/C18H11BrFN3O2S/c19-11-1-6-15-10(7-11)8-16(25-15)14-9-26-18(22-14)23-17(24)21-13-4-2-12(20)3-5-13/h1-9H,(H2,21,22,23,24)
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n/an/a 3.56E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119103
PNG
(CHEMBL3617391)
Show SMILES Brc1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)cc1
Show InChI InChI=1S/C18H11Br2N3O2S/c19-11-1-4-13(5-2-11)21-17(24)23-18-22-14(9-26-18)16-8-10-7-12(20)3-6-15(10)25-16/h1-9H,(H2,21,22,23,24)
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n/an/a 3.58E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119102
PNG
(CHEMBL3617390)
Show SMILES Clc1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)cc1
Show InChI InChI=1S/C18H11BrClN3O2S/c19-11-1-6-15-10(7-11)8-16(25-15)14-9-26-18(22-14)23-17(24)21-13-4-2-12(20)3-5-13/h1-9H,(H2,21,22,23,24)
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n/an/a 3.69E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118815
PNG
(CHEMBL3617374)
Show SMILES Clc1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C18H12ClN3O2S/c19-12-5-7-13(8-6-12)20-17(23)22-18-21-14(10-25-18)16-9-11-3-1-2-4-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 3.86E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119099
PNG
(CHEMBL3617387)
Show SMILES Fc1cccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)c1
Show InChI InChI=1S/C18H11BrFN3O2S/c19-11-4-5-15-10(6-11)7-16(25-15)14-9-26-18(22-14)23-17(24)21-13-3-1-2-12(20)8-13/h1-9H,(H2,21,22,23,24)
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n/an/a 4.02E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50119108
PNG
(CHEMBL3617396)
Show SMILES [O-][N+](=O)c1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccc(F)cc2)n1
Show InChI InChI=1S/C18H11FN4O4S/c19-11-1-3-12(4-2-11)20-17(24)22-18-21-14(9-28-18)16-8-10-7-13(23(25)26)5-6-15(10)27-16/h1-9H,(H2,20,21,22,24)
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n/an/a 4.11E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118821
PNG
(CHEMBL3617368)
Show SMILES [O-][N+](=O)c1cccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)c1
Show InChI InChI=1S/C18H12N4O4S/c23-17(19-12-5-3-6-13(9-12)22(24)25)21-18-20-14(10-27-18)16-8-11-4-1-2-7-15(11)26-16/h1-10H,(H2,19,20,21,23)
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n/an/a 4.12E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118956
PNG
(CHEMBL3617377)
Show SMILES Ic1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C18H12IN3O2S/c19-12-5-7-13(8-6-12)20-17(23)22-18-21-14(10-25-18)16-9-11-3-1-2-4-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 4.13E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118819
PNG
(CHEMBL3617370)
Show SMILES Fc1ccccc1NC(=O)Nc1nc(cs1)-c1cc2ccccc2o1
Show InChI InChI=1S/C18H12FN3O2S/c19-12-6-2-3-7-13(12)20-17(23)22-18-21-14(10-25-18)16-9-11-5-1-4-8-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 4.17E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118861
PNG
(CHEMBL3617367)
Show SMILES [O-][N+](=O)c1ccccc1NC(=O)Nc1nc(cs1)-c1cc2ccccc2o1
Show InChI InChI=1S/C18H12N4O4S/c23-17(19-12-6-2-3-7-14(12)22(24)25)21-18-20-13(10-27-18)16-9-11-5-1-4-8-15(11)26-16/h1-10H,(H2,19,20,21,23)
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n/an/a 4.19E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118815
PNG
(CHEMBL3617374)
Show SMILES Clc1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C18H12ClN3O2S/c19-12-5-7-13(8-6-12)20-17(23)22-18-21-14(10-25-18)16-9-11-3-1-2-4-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 4.26E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119104
PNG
(CHEMBL3617392)
Show SMILES Brc1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccc(I)cc2)n1
Show InChI InChI=1S/C18H11BrIN3O2S/c19-11-1-6-15-10(7-11)8-16(25-15)14-9-26-18(22-14)23-17(24)21-13-4-2-12(20)3-5-13/h1-9H,(H2,21,22,23,24)
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n/an/a 4.36E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119108
PNG
(CHEMBL3617396)
Show SMILES [O-][N+](=O)c1ccc2oc(cc2c1)-c1csc(NC(=O)Nc2ccc(F)cc2)n1
Show InChI InChI=1S/C18H11FN4O4S/c19-11-1-3-12(4-2-11)20-17(24)22-18-21-14(9-28-18)16-8-10-7-13(23(25)26)5-6-15(10)27-16/h1-9H,(H2,20,21,22,24)
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n/an/a 4.76E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118911
PNG
(CHEMBL3617363)
Show SMILES COc1cccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)c1
Show InChI InChI=1S/C19H15N3O3S/c1-24-14-7-4-6-13(10-14)20-18(23)22-19-21-15(11-26-19)17-9-12-5-2-3-8-16(12)25-17/h2-11H,1H3,(H2,20,21,22,23)
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n/an/a 4.89E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118818
PNG
(CHEMBL3617371)
Show SMILES Fc1cccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)c1
Show InChI InChI=1S/C18H12FN3O2S/c19-12-5-3-6-13(9-12)20-17(23)22-18-21-14(10-25-18)16-8-11-4-1-2-7-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 4.90E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119105
PNG
(CHEMBL3617393)
Show SMILES COc1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(ccc3o2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C19H14N4O5S/c1-27-14-5-2-12(3-6-14)20-18(24)22-19-21-15(10-29-19)17-9-11-8-13(23(25)26)4-7-16(11)28-17/h2-10H,1H3,(H2,20,21,22,24)
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n/an/a 4.92E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118814
PNG
(CHEMBL3617375)
Show SMILES Clc1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1Cl
Show InChI InChI=1S/C18H11Cl2N3O2S/c19-12-6-5-11(8-13(12)20)21-17(24)23-18-22-14(9-26-18)16-7-10-3-1-2-4-15(10)25-16/h1-9H,(H2,21,22,23,24)
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n/an/a 5.20E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118895
PNG
(CHEMBL3617364)
Show SMILES COc1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C19H15N3O3S/c1-24-14-8-6-13(7-9-14)20-18(23)22-19-21-15(11-26-19)17-10-12-4-2-3-5-16(12)25-17/h2-11H,1H3,(H2,20,21,22,23)
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n/an/a 5.25E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118817
PNG
(CHEMBL3617372)
Show SMILES Fc1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C18H12FN3O2S/c19-12-5-7-13(8-6-12)20-17(23)22-18-21-14(10-25-18)16-9-11-3-1-2-4-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 5.50E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118797
PNG
(CHEMBL3617376)
Show SMILES Brc1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C18H12BrN3O2S/c19-12-5-7-13(8-6-12)20-17(23)22-18-21-14(10-25-18)16-9-11-3-1-2-4-15(11)24-16/h1-10H,(H2,20,21,22,23)
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n/an/a 5.52E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118890
PNG
(CHEMBL3617365)
Show SMILES Cc1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C19H15N3O2S/c1-12-6-8-14(9-7-12)20-18(23)22-19-21-15(11-25-19)17-10-13-4-2-3-5-16(13)24-17/h2-11H,1H3,(H2,20,21,22,23)
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n/an/a 5.63E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118911
PNG
(CHEMBL3617363)
Show SMILES COc1cccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)c1
Show InChI InChI=1S/C19H15N3O3S/c1-24-14-7-4-6-13(10-14)20-18(23)22-19-21-15(11-26-19)17-9-12-5-2-3-8-16(12)25-17/h2-11H,1H3,(H2,20,21,22,23)
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n/an/a 5.96E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118925
PNG
(CHEMBL3617362)
Show SMILES COc1ccccc1NC(=O)Nc1nc(cs1)-c1cc2ccccc2o1
Show InChI InChI=1S/C19H15N3O3S/c1-24-16-9-5-3-7-13(16)20-18(23)22-19-21-14(11-26-19)17-10-12-6-2-4-8-15(12)25-17/h2-11H,1H3,(H2,20,21,22,23)
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n/an/a 6.10E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119100
PNG
(CHEMBL3617388)
Show SMILES Fc1ccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)cc1
Show InChI InChI=1S/C18H11BrFN3O2S/c19-11-1-6-15-10(7-11)8-16(25-15)14-9-26-18(22-14)23-17(24)21-13-4-2-12(20)3-5-13/h1-9H,(H2,21,22,23,24)
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n/an/a 6.43E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118895
PNG
(CHEMBL3617364)
Show SMILES COc1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C19H15N3O3S/c1-24-14-8-6-13(7-9-14)20-18(23)22-19-21-15(11-26-19)17-10-12-4-2-3-5-16(12)25-17/h2-11H,1H3,(H2,20,21,22,23)
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n/an/a 7.43E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118814
PNG
(CHEMBL3617375)
Show SMILES Clc1ccc(NC(=O)Nc2nc(cs2)-c2cc3ccccc3o2)cc1Cl
Show InChI InChI=1S/C18H11Cl2N3O2S/c19-12-6-5-11(8-13(12)20)21-17(24)23-18-22-14(9-26-18)16-7-10-3-1-2-4-15(10)25-16/h1-9H,(H2,21,22,23,24)
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n/an/a 7.56E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50118957
PNG
(CHEMBL3617378)
Show SMILES COc1ccccc1NC(=O)Nc1nc(cs1)-c1cc2cc(Br)ccc2o1
Show InChI InChI=1S/C19H14BrN3O3S/c1-25-16-5-3-2-4-13(16)21-18(24)23-19-22-14(10-27-19)17-9-11-8-12(20)6-7-15(11)26-17/h2-10H,1H3,(H2,21,22,23,24)
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n/an/a 7.89E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition b...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50119075
PNG
(CHEMBL3617384)
Show SMILES [O-][N+](=O)c1cccc(NC(=O)Nc2nc(cs2)-c2cc3cc(Br)ccc3o2)c1
Show InChI InChI=1S/C18H11BrN4O4S/c19-11-4-5-15-10(6-11)7-16(27-15)14-9-28-18(21-14)22-17(24)20-12-2-1-3-13(8-12)23(25)26/h1-9H,(H2,20,21,22,24)
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n/an/a 7.90E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118861
PNG
(CHEMBL3617367)
Show SMILES [O-][N+](=O)c1ccccc1NC(=O)Nc1nc(cs1)-c1cc2ccccc2o1
Show InChI InChI=1S/C18H12N4O4S/c23-17(19-12-6-2-3-7-14(12)22(24)25)21-18-20-13(10-27-18)16-9-11-5-1-4-8-15(11)26-16/h1-10H,(H2,19,20,21,23)
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n/an/a 7.99E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118925
PNG
(CHEMBL3617362)
Show SMILES COc1ccccc1NC(=O)Nc1nc(cs1)-c1cc2ccccc2o1
Show InChI InChI=1S/C19H15N3O3S/c1-24-16-9-5-3-7-13(16)20-18(23)22-19-21-14(11-26-19)17-10-12-6-2-4-8-15(12)25-17/h2-11H,1H3,(H2,20,21,22,23)
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n/an/a 8.13E+4n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))		BDBM50118957
PNG
(CHEMBL3617378)
Show SMILES COc1ccccc1NC(=O)Nc1nc(cs1)-c1cc2cc(Br)ccc2o1
Show InChI InChI=1S/C19H14BrN3O3S/c1-25-16-5-3-2-4-13(16)21-18(24)23-19-22-14(10-27-19)17-9-11-8-12(20)6-7-15(11)26-17/h2-10H,1H3,(H2,21,22,23,24)
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n/an/a 1.54E+5n/an/an/an/an/an/a



Bezmialem Vakif University

Curated by ChEMBL


Assay Description
Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition ...

Eur J Med Chem 102: 80-92 (2015)


Article DOI: 10.1016/j.ejmech.2015.07.005
BindingDB Entry DOI: 10.7270/Q2JM2CFX
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%