Affinity Data by PubMed id=26275681

PubMed code 26275681

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine/threonine-protein kinase ULK1 (Homo sapiens (Human))	BDBM50111577 (CHEMBL3605055) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of SUMO-tagged ULK1 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase ULK2 (Homo sapiens (Human))	BDBM50111577 (CHEMBL3605055) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of SUMO-tagged ULK2 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Homo sapiens (Human))	BDBM50111575 (CHEMBL3603853) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of recombinant PDK1 (unknown origin) using PDK1tide substrate incubated for 7 mins				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Homo sapiens (Human))	BDBM17051 (BX-795 \| BX-795, 3 \| N-(3-{[5-iodo-4-({3-[(thiophe...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of recombinant PDK1 (unknown origin) using PDK1tide substrate incubated for 7 mins				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase ULK1 (Homo sapiens (Human))	BDBM50111575 (CHEMBL3603853) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of SUMO-tagged ULK1 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase ULK1 (Homo sapiens (Human))	BDBM17051 (BX-795 \| BX-795, 3 \| N-(3-{[5-iodo-4-({3-[(thiophe...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of SUMO-tagged ULK1 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase ULK1 (Homo sapiens (Human))	BDBM50111573 (CHEMBL3605056) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of SUMO-tagged ULK1 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase ULK1 (Homo sapiens (Human))	BDBM50111572 (CHEMBL3605057) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of SUMO-tagged ULK1 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase ULK2 (Homo sapiens (Human))	BDBM50111575 (CHEMBL3603853) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of SUMO-tagged ULK2 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase ULK2 (Homo sapiens (Human))	BDBM50111572 (CHEMBL3605057) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of SUMO-tagged ULK2 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase ULK2 (Homo sapiens (Human))	BDBM17051 (BX-795 \| BX-795, 3 \| N-(3-{[5-iodo-4-({3-[(thiophe...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of SUMO-tagged ULK2 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase ULK2 (Homo sapiens (Human))	BDBM50111573 (CHEMBL3605056) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of SUMO-tagged ULK2 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Homo sapiens (Human))	BDBM50111577 (CHEMBL3605055) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of recombinant PDK1 (unknown origin) using PDK1tide substrate incubated for 7 mins				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Homo sapiens (Human))	BDBM50111572 (CHEMBL3605057) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	421	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of recombinant PDK1 (unknown origin) using PDK1tide substrate incubated for 7 mins				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Homo sapiens (Human))	BDBM50111573 (CHEMBL3605056) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of recombinant PDK1 (unknown origin) using PDK1tide substrate incubated for 7 mins				Bioorg Med Chem 23: 5483-8 (2015) Article DOI: 10.1016/j.bmc.2015.07.034 BindingDB Entry DOI: 10.7270/Q2CN75P8
University of California Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%