Affinity Data by PubMed id=26318997

PubMed code 26318997

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121842 (CHEMBL3617039) Show SMILES O\N=C(/C=C/c1cccnc1)\c1cc2ccccc2cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121843 (CHEMBL3617128) Show SMILES O\N=C(/C=C/c1ccncc1)\c1cc2ccccc2cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121845 (CHEMBL3617130) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121844 (CHEMBL3617129) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121848 (CHEMBL3617038) Show SMILES O\N=C(/C=C/c1ccccn1)\c1cc2ccccc2cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121846 (CHEMBL3617131) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121847 (CHEMBL3617132) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.86E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121842 (CHEMBL3617039) Show SMILES O\N=C(/C=C/c1cccnc1)\c1cc2ccccc2cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121843 (CHEMBL3617128) Show SMILES O\N=C(/C=C/c1ccncc1)\c1cc2ccccc2cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121848 (CHEMBL3617038) Show SMILES O\N=C(/C=C/c1ccccn1)\c1cc2ccccc2cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121845 (CHEMBL3617130) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121844 (CHEMBL3617129) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121846 (CHEMBL3617131) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121847 (CHEMBL3617132) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
University of Technology Sydney Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%