Affinity Data by PubMed id=26385446

PubMed code 26385446

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498654 (CHEMBL3618319) Show SMILES Cc1ccc(CNc2ccnc(Nc3ccc(cc3)C#N)n2)cc1C Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50103642 (4-(6-amino-5-bromo-2-(4-cyanophenylamino)pyrimidin...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498642 (CHEMBL3618312) Show SMILES Cc1ccc(CNc2ccnc(Nc3ccc(cc3)C#N)n2)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498641 (CHEMBL3618310) Show SMILES Fc1cccc(CNc2ccnc(Nc3ccc(cc3)C#N)n2)c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498650 (CHEMBL3618309) Show SMILES Fc1ccccc1CNc1ccnc(Nc2ccc(cc2)C#N)n1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498644 (CHEMBL3618314) Show SMILES COc1cccc(CNc2ccnc(Nc3ccc(cc3)C#N)n2)c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498639 (CHEMBL3618304) Show SMILES Clc1cccc(CNc2ccnc(Nc3ccc(cc3)C#N)n2)c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498653 (CHEMBL3618302) Show SMILES N#Cc1ccc(Nc2nccc(NCc3ccccc3)n2)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM2483 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498638 (CHEMBL3618303) Show SMILES Clc1ccccc1CNc1ccnc(Nc2ccc(cc2)C#N)n1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498652 (CHEMBL3618307) Show SMILES Brc1cccc(CNc2ccnc(Nc3ccc(cc3)C#N)n2)c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498640 (CHEMBL3618308) Show SMILES Brc1ccc(CNc2ccnc(Nc3ccc(cc3)C#N)n2)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498651 (CHEMBL3618305) Show SMILES Clc1ccc(CNc2ccnc(Nc3ccc(cc3)C#N)n2)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498646 (CHEMBL3618320) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498645 (CHEMBL3618318) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498647 (CHEMBL3618306) Show SMILES Brc1ccccc1CNc1ccnc(Nc2ccc(cc2)C#N)n1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498636 (CHEMBL3618315) Show SMILES COc1ccc(CNc2ccnc(Nc3ccc(cc3)C#N)n2)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498637 (CHEMBL3618317) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498648 (CHEMBL3618311) Show SMILES Fc1ccc(CNc2ccnc(Nc3ccc(cc3)C#N)n2)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	382	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498643 (CHEMBL3618313) Show SMILES COc1ccccc1CNc1ccnc(Nc2ccc(cc2)C#N)n1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	936	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM1434 (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...) Show SMILES Cc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50498649 (CHEMBL3618316) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 Reverse transcriptase p66/p51 using poly (rA)-oligo (dT) as template primer after 40 mins by spectrofluorometric analy...				Bioorg Med Chem 23: 6587-93 (2015) Article DOI: 10.1016/j.bmc.2015.09.020 BindingDB Entry DOI: 10.7270/Q2ZS30JJ
Wuhan Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%