| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50498653 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1518191 (CHEMBL3619838) |
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| IC50 | 20±n/a nM |
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| Citation |  Gu, SX; Qiao, H; Zhu, YY; Shu, QC; Liu, H; Ju, XL; De Clercq, E; Balzarini, J; Pannecouque, C A novel family of diarylpyrimidines (DAPYs) featuring a diatomic linker: Design, synthesis and anti-HIV activities. Bioorg Med Chem23:6587-93 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50498653 |
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| n/a |
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| Name | BDBM50498653 |
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| Synonyms: | CHEMBL3618302 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15N5 |
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| Mol. Mass. | 301.3452 |
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| SMILES | N#Cc1ccc(Nc2nccc(NCc3ccccc3)n2)cc1 |
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| Structure | 
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