Affinity Data by PubMed id=26479031

PubMed code 26479031

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499520 (CHEMBL3741559) Show SMILES NCc1ccc(cc1)-c1nc2cc(Cl)ccc2c2NCCCc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499519 (CHEMBL3740980) Show SMILES NCc1ccc(cc1)-c1nc2ccc(Cl)cc2c2NCCc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499526 (CHEMBL3742126) Show SMILES NCc1ccc(cc1)-c1nc2ccc(Cl)cc2c2NCCCc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499516 (CHEMBL3739725) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499524 (CHEMBL3741060) Show SMILES Clc1ccc2nc(-c3ccc(cc3)C#N)c3CCCNc3c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499517 (CHEMBL3739464) Show SMILES Clc1ccc2nc(c3CCNc3c2c1)-c1ccc(cc1)C#N Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499525 (CHEMBL3740568) Show SMILES NCc1ccc(cc1)-c1nc2ccc(Cl)cc2c2NCCCCc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499518 (CHEMBL3740006) Show SMILES Clc1ccc2nc(-c3ccc(cc3)C#N)c3CCCCNc3c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499521 (CHEMBL3741468) Show SMILES Clc1ccc2nc(-c3ccc(cc3)C#N)c3CCCOc3c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499515 (CHEMBL3741946) Show SMILES Clc1ccc2c3NCCCc3c(nc2c1)-c1ccc(cc1)C#N Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499528 (CHEMBL3741859) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499523 (CHEMBL3740513) Show SMILES Clc1ccc2nc(-c3cccs3)c3CCCOc3c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499529 (CHEMBL3741339) Show SMILES Clc1ccc2nc(-c3ccco3)c3CCCOc3c2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499527 (CHEMBL3739752) Show SMILES Clc1ccc2nc(-c3cccs3)c(CCCN3CCCC3)cc2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50499522 (CHEMBL3740078) Show SMILES NCc1ccc(cc1)-c1nc2ccc(Cl)cc2c2OCCCc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus acetylcholinesterase pre-incubated for 20 mins before acetylthiocholine iodide substrate addition by spectroph...				Eur J Med Chem 105: 120-37 (2015) Article DOI: 10.1016/j.ejmech.2015.10.007 BindingDB Entry DOI: 10.7270/Q2GF0XHB
Universitat de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%