Affinity Data by PubMed id=26545798

PubMed code 26545798

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
LIM domain kinase 1 (Homo sapiens (Human))	BDBM50130039 (CHEMBL3629276) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of LIMK1 (unknown origin) using 1 uM cofilin as substrate				Bioorg Med Chem 23: 7464-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.041 BindingDB Entry DOI: 10.7270/Q2Q81FW9
Shanghai Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
LIM domain kinase 1 (Homo sapiens (Human))	BDBM50130038 (CHEMBL3629277) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of LIMK1 (unknown origin) using 1 uM cofilin as substrate				Bioorg Med Chem 23: 7464-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.041 BindingDB Entry DOI: 10.7270/Q2Q81FW9
Shanghai Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
LIM domain kinase 1 (Homo sapiens (Human))	BDBM50130037 (CHEMBL3629278) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of LIMK1 (unknown origin) using 1 uM cofilin as substrate				Bioorg Med Chem 23: 7464-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.041 BindingDB Entry DOI: 10.7270/Q2Q81FW9
Shanghai Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
LIM domain kinase 1 (Homo sapiens (Human))	BDBM50130036 (CHEMBL3629279) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of LIMK1 (unknown origin) using 1 uM cofilin as substrate				Bioorg Med Chem 23: 7464-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.041 BindingDB Entry DOI: 10.7270/Q2Q81FW9
Shanghai Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
LIM domain kinase 1 (Homo sapiens (Human))	BDBM50130035 (CHEMBL3629280) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of LIMK1 (unknown origin) using 1 uM cofilin as substrate				Bioorg Med Chem 23: 7464-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.041 BindingDB Entry DOI: 10.7270/Q2Q81FW9
Shanghai Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50130036 (CHEMBL3629279) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) after 4 hrs using 1 uM STK2 as substrate				Bioorg Med Chem 23: 7464-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.041 BindingDB Entry DOI: 10.7270/Q2Q81FW9
Shanghai Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50130037 (CHEMBL3629278) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) after 4 hrs using 1 uM STK2 as substrate				Bioorg Med Chem 23: 7464-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.041 BindingDB Entry DOI: 10.7270/Q2Q81FW9
Shanghai Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50130038 (CHEMBL3629277) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) after 4 hrs using 1 uM STK2 as substrate				Bioorg Med Chem 23: 7464-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.041 BindingDB Entry DOI: 10.7270/Q2Q81FW9
Shanghai Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50130035 (CHEMBL3629280) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) after 4 hrs using 1 uM STK2 as substrate				Bioorg Med Chem 23: 7464-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.041 BindingDB Entry DOI: 10.7270/Q2Q81FW9
Shanghai Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50130039 (CHEMBL3629276) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) after 4 hrs using 1 uM STK2 as substrate				Bioorg Med Chem 23: 7464-77 (2015) Article DOI: 10.1016/j.bmc.2015.10.041 BindingDB Entry DOI: 10.7270/Q2Q81FW9
Shanghai Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%