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PubMed code 26552700

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM50266292
PNG
(CHEMBL3906203)
Show SMILES CCC(=O)N1CCOc2c(C1)cc(cc2OCC1CCCN(C)C1)-c1ccc(OC)c(OC)c1
Show InChI InChI=1S/C22H17N3O3/c1-12-10-17-18(24(3)22(28)23(17)2)11-16(12)25-20(26)14-8-4-6-13-7-5-9-15(19(13)14)21(25)27/h4-11H,1-3H3
PDB
MMDB

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KEGG

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PC cid
PC sid
PDB
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Similars

PDB
Article
PubMed
n/an/a 324n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Alphascreen assay. Binding to CREBBPA (domain start/stop: R1081-G1197) by alphascreen assay


Cancer Res 75: 5106-5119 (2015)


Article DOI: 10.1158/0008-5472.CAN-15-0236
BindingDB Entry DOI: 10.7270/Q2HQ43GJ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Bromodomain-containing protein 4


(Homo sapiens (Human))
BDBM50266292
PNG
(CHEMBL3906203)
Show SMILES CCC(=O)N1CCOc2c(C1)cc(cc2OCC1CCCN(C)C1)-c1ccc(OC)c(OC)c1
Show InChI InChI=1S/C22H17N3O3/c1-12-10-17-18(24(3)22(28)23(17)2)11-16(12)25-20(26)14-8-4-6-13-7-5-9-15(19(13)14)21(25)27/h4-11H,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 2.46E+3n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Alphascreen assay. Binding to BRD4A (domain start/stop: N44-E168) by alphascreen assay


Cancer Res 75: 5106-5119 (2015)


Article DOI: 10.1158/0008-5472.CAN-15-0236
BindingDB Entry DOI: 10.7270/Q2HQ43GJ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%