BindingDB logo
myBDB logout

PubMed code 26620718

Compile data set for download or QSAR
Found 37 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM23223
PNG
(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Show SMILES CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O |(-4.44,-1.63,;-5.78,-.86,;-7.11,-1.63,;-5.78,.68,;-7.11,1.45,;-8.44,.68,;-7.11,2.99,;-8.44,3.76,;-5.78,3.76,;-5.78,5.3,;-4.44,6.07,;-4.44,2.99,;-3.11,3.76,;-3.11,5.3,;-1.77,2.99,;-1.77,1.45,;-.44,.68,;-3.11,.68,;-4.44,1.45,;-.44,3.76,;-.44,5.3,;-1.77,6.07,;.89,6.07,;2.23,5.3,;3.56,6.07,;3.56,7.61,;4.89,8.38,;2.23,8.38,;4.89,5.3,;6.23,6.07,;4.89,3.76,;6.23,2.99,;3.56,2.99,;3.56,1.45,;4.89,.68,;2.23,3.76,;.89,2.99,;.89,1.45,)|
Show InChI InChI=1S/C30H30O8/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36/h7-12,33-38H,1-6H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
 390n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50206519
PNG
(CHEMBL3735206)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C37H36BrClN4O9S/c1-37(2,3)52-36(46)42-22-28(51-27-15-11-25(12-16-27)24-7-5-4-6-8-24)20-33(42)35(45)40-31(19-23-9-13-26(38)14-10-23)34(44)41-53(49,50)29-17-18-30(39)32(21-29)43(47)48/h4-18,21,28,31,33H,19-20,22H2,1-3H3,(H,40,45)(H,41,44)/t28-,31-,33-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 530n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50206529
PNG
(CHEMBL3736193)
Show SMILES Cc1ccc(cc1)-c1ccc(O[C@H]2C[C@H](N(C2)C(=O)OC(C)(C)C)C(=O)N[C@@H](Cc2ccc(Br)cc2)C(=O)NS(=O)(=O)c2ccc(Cl)c(c2)[N+]([O-])=O)cc1 |r|
Show InChI InChI=1S/C38H38BrClN4O9S/c1-23-5-9-25(10-6-23)26-11-15-28(16-12-26)52-29-20-34(43(22-29)37(47)53-38(2,3)4)36(46)41-32(19-24-7-13-27(39)14-8-24)35(45)42-54(50,51)30-17-18-31(40)33(21-30)44(48)49/h5-18,21,29,32,34H,19-20,22H2,1-4H3,(H,41,46)(H,42,45)/t29-,32-,34-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 550n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Bcl-2 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50206540
PNG
(CHEMBL3735093)
Show SMILES Cc1ccc(cc1)-c1ccc(O[C@H]2C[C@H](N(C2)C(=O)OC(C)(C)C)C(=O)N[C@@H](Cc2ccccc2)C(=O)NS(=O)(=O)c2ccc(Cl)c(c2)[N+]([O-])=O)cc1 |r|
Show InChI InChI=1S/C38H39ClN4O9S/c1-24-10-12-26(13-11-24)27-14-16-28(17-15-27)51-29-21-34(42(23-29)37(46)52-38(2,3)4)36(45)40-32(20-25-8-6-5-7-9-25)35(44)41-53(49,50)30-18-19-31(39)33(22-30)43(47)48/h5-19,22,29,32,34H,20-21,23H2,1-4H3,(H,40,45)(H,41,44)/t29-,32-,34-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 560n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM23223
PNG
(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Show SMILES CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O |(-4.44,-1.63,;-5.78,-.86,;-7.11,-1.63,;-5.78,.68,;-7.11,1.45,;-8.44,.68,;-7.11,2.99,;-8.44,3.76,;-5.78,3.76,;-5.78,5.3,;-4.44,6.07,;-4.44,2.99,;-3.11,3.76,;-3.11,5.3,;-1.77,2.99,;-1.77,1.45,;-.44,.68,;-3.11,.68,;-4.44,1.45,;-.44,3.76,;-.44,5.3,;-1.77,6.07,;.89,6.07,;2.23,5.3,;3.56,6.07,;3.56,7.61,;4.89,8.38,;2.23,8.38,;4.89,5.3,;6.23,6.07,;4.89,3.76,;6.23,2.99,;3.56,2.99,;3.56,1.45,;4.89,.68,;2.23,3.76,;.89,2.99,;.89,1.45,)|
Show InChI InChI=1S/C30H30O8/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36/h7-12,33-38H,1-6H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
 560n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Bcl-2 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50206516
PNG
(CHEMBL3736460)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C37H35BrCl2N4O9S/c1-37(2,3)53-36(47)43-21-28(52-27-14-8-24(9-15-27)23-6-12-26(39)13-7-23)19-33(43)35(46)41-31(18-22-4-10-25(38)11-5-22)34(45)42-54(50,51)29-16-17-30(40)32(20-29)44(48)49/h4-17,20,28,31,33H,18-19,21H2,1-3H3,(H,41,46)(H,42,45)/t28-,31-,33-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 580n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50206529
PNG
(CHEMBL3736193)
Show SMILES Cc1ccc(cc1)-c1ccc(O[C@H]2C[C@H](N(C2)C(=O)OC(C)(C)C)C(=O)N[C@@H](Cc2ccc(Br)cc2)C(=O)NS(=O)(=O)c2ccc(Cl)c(c2)[N+]([O-])=O)cc1 |r|
Show InChI InChI=1S/C38H38BrClN4O9S/c1-23-5-9-25(10-6-23)26-11-15-28(16-12-26)52-29-20-34(43(22-29)37(47)53-38(2,3)4)36(46)41-32(19-24-7-13-27(39)14-8-24)35(45)42-54(50,51)30-17-18-31(40)33(21-30)44(48)49/h5-18,21,29,32,34H,19-20,22H2,1-4H3,(H,41,46)(H,42,45)/t29-,32-,34-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 630n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499415
PNG
(CHEMBL3735919)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)cc1)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C37H37BrClN3O7S/c1-37(2,3)49-36(45)42-23-30(48-29-17-11-26(12-18-29)25-7-5-4-6-8-25)22-33(42)35(44)40-32(21-24-9-13-27(38)14-10-24)34(43)41-50(46,47)31-19-15-28(39)16-20-31/h4-20,30,32-33H,21-23H2,1-3H3,(H,40,44)(H,41,43)/t30-,32-,33-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 740n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Bcl-2-like protein 1


(Homo sapiens (Human))		BDBM23223
PNG
(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Show SMILES CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O |(-4.44,-1.63,;-5.78,-.86,;-7.11,-1.63,;-5.78,.68,;-7.11,1.45,;-8.44,.68,;-7.11,2.99,;-8.44,3.76,;-5.78,3.76,;-5.78,5.3,;-4.44,6.07,;-4.44,2.99,;-3.11,3.76,;-3.11,5.3,;-1.77,2.99,;-1.77,1.45,;-.44,.68,;-3.11,.68,;-4.44,1.45,;-.44,3.76,;-.44,5.3,;-1.77,6.07,;.89,6.07,;2.23,5.3,;3.56,6.07,;3.56,7.61,;4.89,8.38,;2.23,8.38,;4.89,5.3,;6.23,6.07,;4.89,3.76,;6.23,2.99,;3.56,2.99,;3.56,1.45,;4.89,.68,;2.23,3.76,;.89,2.99,;.89,1.45,)|
Show InChI InChI=1S/C30H30O8/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36/h7-12,33-38H,1-6H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
 770n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Bcl-XL (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition an...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50206516
PNG
(CHEMBL3736460)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C37H35BrCl2N4O9S/c1-37(2,3)53-36(47)43-21-28(52-27-14-8-24(9-15-27)23-6-12-26(39)13-7-23)19-33(43)35(46)41-31(18-22-4-10-25(38)11-5-22)34(45)42-54(50,51)29-16-17-30(40)32(20-29)44(48)49/h4-17,20,28,31,33H,18-19,21H2,1-3H3,(H,41,46)(H,42,45)/t28-,31-,33-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 830n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Bcl-2 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50206519
PNG
(CHEMBL3735206)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C37H36BrClN4O9S/c1-37(2,3)52-36(46)42-22-28(51-27-15-11-25(12-16-27)24-7-5-4-6-8-24)20-33(42)35(45)40-31(19-23-9-13-26(38)14-10-23)34(44)41-53(49,50)29-17-18-30(39)32(21-29)43(47)48/h4-18,21,28,31,33H,19-20,22H2,1-3H3,(H,40,45)(H,41,44)/t28-,31-,33-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 930n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Bcl-2 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499423
PNG
(CHEMBL3735052)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C37H37ClN4O9S/c1-37(2,3)51-36(45)41-23-28(50-27-16-14-26(15-17-27)25-12-8-5-9-13-25)21-33(41)35(44)39-31(20-24-10-6-4-7-11-24)34(43)40-52(48,49)29-18-19-30(38)32(22-29)42(46)47/h4-19,22,28,31,33H,20-21,23H2,1-3H3,(H,39,44)(H,40,43)/t28-,31-,33-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 940n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499416
PNG
(CHEMBL3735669)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)[C@H](Cc1ccc(Br)cc1)NC(=O)[C@@H]1C[C@@H](CN1C(=O)OC(C)(C)C)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C38H40BrN3O7S/c1-25-10-20-32(21-11-25)50(46,47)41-35(43)33(22-26-12-16-29(39)17-13-26)40-36(44)34-23-31(24-42(34)37(45)49-38(2,3)4)48-30-18-14-28(15-19-30)27-8-6-5-7-9-27/h5-21,31,33-34H,22-24H2,1-4H3,(H,40,44)(H,41,43)/t31-,33-,34-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 990n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499406
PNG
(CHEMBL3736279)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C39H38ClN5O9S/c1-39(2,3)54-38(48)44-23-28(53-27-15-13-25(14-16-27)24-9-5-4-6-10-24)20-35(44)37(47)42-33(19-26-22-41-32-12-8-7-11-30(26)32)36(46)43-55(51,52)29-17-18-31(40)34(21-29)45(49)50/h4-18,21-22,28,33,35,41H,19-20,23H2,1-3H3,(H,42,47)(H,43,46)/t28-,33-,35-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 1.20E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499413
PNG
(CHEMBL3735545)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)NS(=O)(=O)c1ccccc1)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C37H38BrN3O7S/c1-37(2,3)48-36(44)41-24-30(47-29-20-16-27(17-21-29)26-10-6-4-7-11-26)23-33(41)35(43)39-32(22-25-14-18-28(38)19-15-25)34(42)40-49(45,46)31-12-8-5-9-13-31/h4-21,30,32-33H,22-24H2,1-3H3,(H,39,43)(H,40,42)/t30-,32-,33-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 1.20E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Bcl-2-like protein 1


(Homo sapiens (Human))		BDBM50206529
PNG
(CHEMBL3736193)
Show SMILES Cc1ccc(cc1)-c1ccc(O[C@H]2C[C@H](N(C2)C(=O)OC(C)(C)C)C(=O)N[C@@H](Cc2ccc(Br)cc2)C(=O)NS(=O)(=O)c2ccc(Cl)c(c2)[N+]([O-])=O)cc1 |r|
Show InChI InChI=1S/C38H38BrClN4O9S/c1-23-5-9-25(10-6-23)26-11-15-28(16-12-26)52-29-20-34(43(22-29)37(47)53-38(2,3)4)36(46)41-32(19-24-7-13-27(39)14-8-24)35(45)42-54(50,51)30-17-18-31(40)33(21-30)44(48)49/h5-18,21,29,32,34H,19-20,22H2,1-4H3,(H,41,46)(H,42,45)/t29-,32-,34-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 1.20E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Bcl-XL (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition an...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499420
PNG
(CHEMBL3735578)
Show SMILES Cc1ccc(cc1)-c1ccc(O[C@H]2C[C@H](N(C2)C(=O)OC(C)(C)C)C(=O)N[C@@H](Cc2ccccc2)C(=O)NS(=O)(=O)c2ccccc2)cc1 |r|
Show InChI InChI=1S/C38H41N3O7S/c1-26-15-17-28(18-16-26)29-19-21-30(22-20-29)47-31-24-34(41(25-31)37(44)48-38(2,3)4)36(43)39-33(23-27-11-7-5-8-12-27)35(42)40-49(45,46)32-13-9-6-10-14-32/h5-22,31,33-34H,23-25H2,1-4H3,(H,39,43)(H,40,42)/t31-,33-,34-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 1.60E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499405
PNG
(CHEMBL3734919)
Show SMILES Cc1ccc(cc1)-c1ccc(O[C@H]2C[C@H](N(C2)C(=O)OC(C)(C)C)C(=O)N[C@@H](Cc2ccccc2)C(=O)NS(=O)(=O)c2ccc(C)cc2)cc1 |r|
Show InChI InChI=1S/C39H43N3O7S/c1-26-11-15-29(16-12-26)30-17-19-31(20-18-30)48-32-24-35(42(25-32)38(45)49-39(3,4)5)37(44)40-34(23-28-9-7-6-8-10-28)36(43)41-50(46,47)33-21-13-27(2)14-22-33/h6-22,32,34-35H,23-25H2,1-5H3,(H,40,44)(H,41,43)/t32-,34-,35-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 1.90E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Bcl-2-like protein 1


(Homo sapiens (Human))		BDBM50206516
PNG
(CHEMBL3736460)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C37H35BrCl2N4O9S/c1-37(2,3)53-36(47)43-21-28(52-27-14-8-24(9-15-27)23-6-12-26(39)13-7-23)19-33(43)35(46)41-31(18-22-4-10-25(38)11-5-22)34(45)42-54(50,51)29-16-17-30(40)32(20-29)44(48)49/h4-17,20,28,31,33H,18-19,21H2,1-3H3,(H,41,46)(H,42,45)/t28-,31-,33-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 2.10E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Bcl-XL (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition an...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499407
PNG
(CHEMBL3736136)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)NS(=O)(=O)c1ccc(cc1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C37H37BrN4O9S/c1-37(2,3)51-36(45)41-23-30(50-29-17-11-26(12-18-29)25-7-5-4-6-8-25)22-33(41)35(44)39-32(21-24-9-13-27(38)14-10-24)34(43)40-52(48,49)31-19-15-28(16-20-31)42(46)47/h4-20,30,32-33H,21-23H2,1-3H3,(H,39,44)(H,40,43)/t30-,32-,33-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 2.20E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499404
PNG
(CHEMBL3736270)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C37H37ClN4O10S/c1-37(2,3)52-36(46)41-22-28(51-27-15-11-25(12-16-27)24-7-5-4-6-8-24)20-33(41)35(45)39-31(19-23-9-13-26(43)14-10-23)34(44)40-53(49,50)29-17-18-30(38)32(21-29)42(47)48/h4-18,21,28,31,33,43H,19-20,22H2,1-3H3,(H,39,45)(H,40,44)/t28-,31-,33-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 2.20E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Bcl-2-like protein 1


(Homo sapiens (Human))		BDBM50206519
PNG
(CHEMBL3735206)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C37H36BrClN4O9S/c1-37(2,3)52-36(46)42-22-28(51-27-15-11-25(12-16-27)24-7-5-4-6-8-24)20-33(42)35(45)40-31(19-23-9-13-26(38)14-10-23)34(44)41-53(49,50)29-17-18-30(39)32(21-29)43(47)48/h4-18,21,28,31,33H,19-20,22H2,1-3H3,(H,40,45)(H,41,44)/t28-,31-,33-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 2.20E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Bcl-XL (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition an...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499403
PNG
(CHEMBL3735717)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NS(=O)(=O)c1ccccc1)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C39H40N4O7S/c1-39(2,3)50-38(46)43-25-30(49-29-20-18-27(19-21-29)26-12-6-4-7-13-26)23-35(43)37(45)41-34(22-28-24-40-33-17-11-10-16-32(28)33)36(44)42-51(47,48)31-14-8-5-9-15-31/h4-21,24,30,34-35,40H,22-23,25H2,1-3H3,(H,41,45)(H,42,44)/t30-,34-,35-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 3.20E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499417
PNG
(CHEMBL3736039)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1C[C@@H](CN1C(=O)OC(C)(C)C)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C38H41N3O7S/c1-26-15-21-32(22-16-26)49(45,46)40-35(42)33(23-27-11-7-5-8-12-27)39-36(43)34-24-31(25-41(34)37(44)48-38(2,3)4)47-30-19-17-29(18-20-30)28-13-9-6-10-14-28/h5-22,31,33-34H,23-25H2,1-4H3,(H,39,43)(H,40,42)/t31-,33-,34-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 3.30E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50206540
PNG
(CHEMBL3735093)
Show SMILES Cc1ccc(cc1)-c1ccc(O[C@H]2C[C@H](N(C2)C(=O)OC(C)(C)C)C(=O)N[C@@H](Cc2ccccc2)C(=O)NS(=O)(=O)c2ccc(Cl)c(c2)[N+]([O-])=O)cc1 |r|
Show InChI InChI=1S/C38H39ClN4O9S/c1-24-10-12-26(13-11-24)27-14-16-28(17-15-27)51-29-21-34(42(23-29)37(46)52-38(2,3)4)36(45)40-32(20-25-8-6-5-7-9-25)35(44)41-53(49,50)30-18-19-31(39)33(22-30)43(47)48/h5-19,22,29,32,34H,20-21,23H2,1-4H3,(H,40,45)(H,41,44)/t29-,32-,34-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 4.60E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Bcl-2 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499422
PNG
(CHEMBL3735067)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)NS(=O)(=O)c1ccccc1)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C37H39N3O7S/c1-37(2,3)47-36(43)40-25-30(46-29-21-19-28(20-22-29)27-15-9-5-10-16-27)24-33(40)35(42)38-32(23-26-13-7-4-8-14-26)34(41)39-48(44,45)31-17-11-6-12-18-31/h4-22,30,32-33H,23-25H2,1-3H3,(H,38,42)(H,39,41)/t30-,32-,33-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 6.40E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499412
PNG
(CHEMBL3736139)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C31H34N2O6/c1-31(2,3)39-30(37)33-20-25(38-24-16-14-23(15-17-24)22-12-8-5-9-13-22)19-27(33)28(34)32-26(29(35)36)18-21-10-6-4-7-11-21/h4-17,25-27H,18-20H2,1-3H3,(H,32,34)(H,35,36)/t25-,26-,27-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 8.40E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Bcl-2-like protein 1


(Homo sapiens (Human))		BDBM50206540
PNG
(CHEMBL3735093)
Show SMILES Cc1ccc(cc1)-c1ccc(O[C@H]2C[C@H](N(C2)C(=O)OC(C)(C)C)C(=O)N[C@@H](Cc2ccccc2)C(=O)NS(=O)(=O)c2ccc(Cl)c(c2)[N+]([O-])=O)cc1 |r|
Show InChI InChI=1S/C38H39ClN4O9S/c1-24-10-12-26(13-11-24)27-14-16-28(17-15-27)51-29-21-34(42(23-29)37(46)52-38(2,3)4)36(45)40-32(20-25-8-6-5-7-9-25)35(44)41-53(49,50)30-18-19-31(39)33(22-30)43(47)48/h5-19,22,29,32,34H,20-21,23H2,1-4H3,(H,40,45)(H,41,44)/t29-,32-,34-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 8.70E+3n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Bcl-XL (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition an...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499421
PNG
(CHEMBL3735834)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)NCC(O)=O)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C24H28N2O6/c1-24(2,3)32-23(30)26-15-19(13-20(26)22(29)25-14-21(27)28)31-18-11-9-17(10-12-18)16-7-5-4-6-8-16/h4-12,19-20H,13-15H2,1-3H3,(H,25,29)(H,27,28)/t19-,20-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499409
PNG
(CHEMBL3734781)
Show SMILES CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](CN1C(=O)OC(C)(C)C)Oc1ccc(cc1)-c1ccccc1)C(O)=O |r|
Show InChI InChI=1S/C27H34N2O6/c1-17(2)23(25(31)32)28-24(30)22-15-21(16-29(22)26(33)35-27(3,4)5)34-20-13-11-19(12-14-20)18-9-7-6-8-10-18/h6-14,17,21-23H,15-16H2,1-5H3,(H,28,30)(H,31,32)/t21-,22-,23-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499411
PNG
(CHEMBL3736148)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@H](C(O)=O)c1ccccc1)Oc1ccc(Br)cc1 |r|
Show InChI InChI=1S/C24H27BrN2O6/c1-24(2,3)33-23(31)27-14-18(32-17-11-9-16(25)10-12-17)13-19(27)21(28)26-20(22(29)30)15-7-5-4-6-8-15/h4-12,18-20H,13-14H2,1-3H3,(H,26,28)(H,29,30)/t18-,19-,20-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499410
PNG
(CHEMBL3735810)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@H](C(O)=O)c1ccccc1)Oc1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C30H32N2O6/c1-30(2,3)38-29(36)32-19-24(37-23-16-14-21(15-17-23)20-10-6-4-7-11-20)18-25(32)27(33)31-26(28(34)35)22-12-8-5-9-13-22/h4-17,24-26H,18-19H2,1-3H3,(H,31,33)(H,34,35)/t24-,25-,26-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499419
PNG
(CHEMBL3735219)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O)Oc1ccc(Br)cc1 |r|
Show InChI InChI=1S/C25H29BrN2O6/c1-25(2,3)34-24(32)28-15-19(33-18-11-9-17(26)10-12-18)14-21(28)22(29)27-20(23(30)31)13-16-7-5-4-6-8-16/h4-12,19-21H,13-15H2,1-3H3,(H,27,29)(H,30,31)/t19-,20-,21-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499414
PNG
(CHEMBL3736152)
Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)NCC(O)=O)Oc1ccc(Br)cc1 |r|
Show InChI InChI=1S/C18H23BrN2O6/c1-18(2,3)27-17(25)21-10-13(26-12-6-4-11(19)5-7-12)8-14(21)16(24)20-9-15(22)23/h4-7,13-14H,8-10H2,1-3H3,(H,20,24)(H,22,23)/t13-,14-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499418
PNG
(CHEMBL3735269)
Show SMILES CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](CN1C(=O)OC(C)(C)C)Oc1ccc(Br)cc1)C(O)=O |r|
Show InChI InChI=1S/C21H29BrN2O6/c1-12(2)17(19(26)27)23-18(25)16-10-15(29-14-8-6-13(22)7-9-14)11-24(16)20(28)30-21(3,4)5/h6-9,12,15-17H,10-11H2,1-5H3,(H,23,25)(H,26,27)/t15-,16-,17-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499408
PNG
(CHEMBL3736200)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1C[C@@H](CN1C(=O)OC(C)(C)C)Oc1ccc(Br)cc1)C(O)=O |r|
Show InChI InChI=1S/C22H31BrN2O6/c1-13(2)10-17(20(27)28)24-19(26)18-11-16(30-15-8-6-14(23)7-9-15)12-25(18)21(29)31-22(3,4)5/h6-9,13,16-18H,10-12H2,1-5H3,(H,24,26)(H,27,28)/t16-,17-,18-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50499402
PNG
(CHEMBL3735477)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1C[C@@H](CN1C(=O)OC(C)(C)C)Oc1ccc(cc1)-c1ccccc1)C(O)=O |r|
Show InChI InChI=1S/C28H36N2O6/c1-18(2)15-23(26(32)33)29-25(31)24-16-22(17-30(24)27(34)36-28(3,4)5)35-21-13-11-20(12-14-21)19-9-7-6-8-10-19/h6-14,18,22-24H,15-17H2,1-5H3,(H,29,31)(H,32,33)/t22-,23-,24-/m0/s1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...

Bioorg Med Chem 23: 7685-93 (2015)


Article DOI: 10.1016/j.bmc.2015.11.014
BindingDB Entry DOI: 10.7270/Q2445QG3
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%