Found 145 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cytochrome P450 1A2
(Homo sapiens (Human)) | BDBM50143061
(CHEMBL3759901)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(Cl)cc2C1=O Show InChI InChI=1S/C11H8N6O3/c12-11-13-8-7(9(18)14-11)15-17(16-8)6-3-1-2-5(4-6)10(19)20/h1-4H,(H,19,20)(H3,12,13,14,16,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
MMDB
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP1A2 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 1A2
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP1A2 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50143060
(CHEMBL3758305)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(C)c2C1=O Show InChI InChI=1S/C7H9N3O3/c1-2-13-6(12)4-3-9-7(8)10-5(4)11/h3H,2H2,1H3,(H3,8,9,10,11) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50143061
(CHEMBL3759901)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(Cl)cc2C1=O Show InChI InChI=1S/C11H8N6O3/c12-11-13-8-7(9(18)14-11)15-17(16-8)6-3-1-2-5(4-6)10(19)20/h1-4H,(H,19,20)(H3,12,13,14,16,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 1A2
(Homo sapiens (Human)) | BDBM50143062
(CHEMBL3758435)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(F)cc2C1=O Show InChI InChI=1S/C11H10BrN3O/c1-15-10(16)8(12)9(14-11(15)13)7-5-3-2-4-6-7/h2-6H,1H3,(H2,13,14) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP1A2 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50143062
(CHEMBL3758435)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(F)cc2C1=O Show InChI InChI=1S/C11H10BrN3O/c1-15-10(16)8(12)9(14-11(15)13)7-5-3-2-4-6-7/h2-6H,1H3,(H2,13,14) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50143061
(CHEMBL3759901)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(Cl)cc2C1=O Show InChI InChI=1S/C11H8N6O3/c12-11-13-8-7(9(18)14-11)15-17(16-8)6-3-1-2-5(4-6)10(19)20/h1-4H,(H,19,20)(H3,12,13,14,16,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50143063
(CHEMBL3758465)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(F)c2C1=O Show InChI InChI=1S/C20H13F6N7O2/c21-19(22,23)11-4-9(5-12(7-11)20(24,25)26)8-28-16(34)10-2-1-3-13(6-10)33-31-14-15(32-33)29-18(27)30-17(14)35/h1-7H,8H2,(H,28,34)(H3,27,29,30,32,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50143061
(CHEMBL3759901)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(Cl)cc2C1=O Show InChI InChI=1S/C11H8N6O3/c12-11-13-8-7(9(18)14-11)15-17(16-8)6-3-1-2-5(4-6)10(19)20/h1-4H,(H,19,20)(H3,12,13,14,16,18) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 1A2
(Homo sapiens (Human)) | BDBM50143063
(CHEMBL3758465)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(F)c2C1=O Show InChI InChI=1S/C20H13F6N7O2/c21-19(22,23)11-4-9(5-12(7-11)20(24,25)26)8-28-16(34)10-2-1-3-13(6-10)33-31-14-15(32-33)29-18(27)30-17(14)35/h1-7H,8H2,(H,28,34)(H3,27,29,30,32,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP1A2 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50143060
(CHEMBL3758305)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(C)c2C1=O Show InChI InChI=1S/C7H9N3O3/c1-2-13-6(12)4-3-9-7(8)10-5(4)11/h3H,2H2,1H3,(H3,8,9,10,11) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50143063
(CHEMBL3758465)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(F)c2C1=O Show InChI InChI=1S/C20H13F6N7O2/c21-19(22,23)11-4-9(5-12(7-11)20(24,25)26)8-28-16(34)10-2-1-3-13(6-10)33-31-14-15(32-33)29-18(27)30-17(14)35/h1-7H,8H2,(H,28,34)(H3,27,29,30,32,35) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50143062
(CHEMBL3758435)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(F)cc2C1=O Show InChI InChI=1S/C11H10BrN3O/c1-15-10(16)8(12)9(14-11(15)13)7-5-3-2-4-6-7/h2-6H,1H3,(H2,13,14) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 1A2
(Homo sapiens (Human)) | BDBM50143060
(CHEMBL3758305)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(C)c2C1=O Show InChI InChI=1S/C7H9N3O3/c1-2-13-6(12)4-3-9-7(8)10-5(4)11/h3H,2H2,1H3,(H3,8,9,10,11) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP1A2 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50143063
(CHEMBL3758465)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(F)c2C1=O Show InChI InChI=1S/C20H13F6N7O2/c21-19(22,23)11-4-9(5-12(7-11)20(24,25)26)8-28-16(34)10-2-1-3-13(6-10)33-31-14-15(32-33)29-18(27)30-17(14)35/h1-7H,8H2,(H,28,34)(H3,27,29,30,32,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50143062
(CHEMBL3758435)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(F)cc2C1=O Show InChI InChI=1S/C11H10BrN3O/c1-15-10(16)8(12)9(14-11(15)13)7-5-3-2-4-6-7/h2-6H,1H3,(H2,13,14) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50143060
(CHEMBL3758305)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(C)c2C1=O Show InChI InChI=1S/C7H9N3O3/c1-2-13-6(12)4-3-9-7(8)10-5(4)11/h3H,2H2,1H3,(H3,8,9,10,11) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 (unknown origin) |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50143060
(CHEMBL3758305)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(C)c2C1=O Show InChI InChI=1S/C7H9N3O3/c1-2-13-6(12)4-3-9-7(8)10-5(4)11/h3H,2H2,1H3,(H3,8,9,10,11) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu5 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50143061
(CHEMBL3759901)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(Cl)cc2C1=O Show InChI InChI=1S/C11H8N6O3/c12-11-13-8-7(9(18)14-11)15-17(16-8)6-3-1-2-5(4-6)10(19)20/h1-4H,(H,19,20)(H3,12,13,14,16,18) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu5 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143155
(CHEMBL3758986)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-24-7-6-22-16(24)17(26)23-11-3-5-15(14(20)9-11)25-18(27)12-4-2-10(21)8-13(12)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 676 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143158
(CHEMBL3758228)Show SMILES Cc1cccc2C(=O)N(C(=O)c12)c1ccc(NC(=O)c2nccn2C)cc1Cl Show InChI InChI=1S/C20H15ClN4O3/c1-11-4-3-5-13-16(11)20(28)25(19(13)27)15-7-6-12(10-14(15)21)23-18(26)17-22-8-9-24(17)2/h3-10H,1-2H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143160
(CHEMBL3759573)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H11ClN4O3S/c1-9-14(21-8-27-9)16(24)22-10-4-5-13(12(19)7-10)23-17(25)11-3-2-6-20-15(11)18(23)26/h2-8H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 191 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143160
(CHEMBL3759573)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H11ClN4O3S/c1-9-14(21-8-27-9)16(24)22-10-4-5-13(12(19)7-10)23-17(25)11-3-2-6-20-15(11)18(23)26/h2-8H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 191 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143163
(CHEMBL3758756)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O3S/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(13(21)7-10)24-18(26)11-3-2-4-12(20)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.38E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143164
(CHEMBL3758216)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O3S/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(21)7-11)24-18(26)12-4-2-10(20)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143166
(CHEMBL3759038)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccc(C)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3S/c1-10-3-5-13-14(7-10)20(27)24(19(13)26)16-6-4-12(8-15(16)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143076
(CHEMBL3758587)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(C)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O4/c1-10-3-5-13-14(7-10)20(27)24(19(13)26)16-6-4-12(8-15(16)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 41 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143170
(CHEMBL3758364)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H13ClN4O3/c1-23-9-8-21-16(23)17(25)22-11-6-7-15(14(20)10-11)24-18(26)12-4-2-3-5-13(12)19(24)27/h2-10H,1H3,(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 355 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143176
(CHEMBL3759137)Show SMILES Cc1ccsc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H13ClN2O3S/c1-11-8-9-27-17(11)18(24)22-12-6-7-16(15(21)10-12)23-19(25)13-4-2-3-5-14(13)20(23)26/h2-10H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.91E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143178
(CHEMBL3759994)Show SMILES Cc1[nH]ccc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3/c1-11-13(8-9-22-11)18(25)23-12-6-7-17(16(21)10-12)24-19(26)14-4-2-3-5-15(14)20(24)27/h2-10,22H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143157
(CHEMBL3759647)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-24-7-6-22-16(24)17(26)23-11-3-5-15(14(21)9-11)25-18(27)12-4-2-10(20)8-13(12)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.57E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143152
(CHEMBL3759656)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccc(C)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H15ClN4O3/c1-10-3-5-13-14(7-10)20(28)25(19(13)27)16-6-4-12(8-15(16)21)23-18(26)17-11(2)9-22-24-17/h3-9H,1-2H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.75E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143086
(CHEMBL3759289)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O4/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(21)7-11)24-18(26)12-4-2-10(20)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 405 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50143063
(CHEMBL3758465)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(F)c2C1=O Show InChI InChI=1S/C20H13F6N7O2/c21-19(22,23)11-4-9(5-12(7-11)20(24,25)26)8-28-16(34)10-2-1-3-13(6-10)33-31-14-15(32-33)29-18(27)30-17(14)35/h1-7H,8H2,(H,28,34)(H3,27,29,30,32,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu5 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143060
(CHEMBL3758305)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(C)c2C1=O Show InChI InChI=1S/C7H9N3O3/c1-2-13-6(12)4-3-9-7(8)10-5(4)11/h3H,2H2,1H3,(H3,8,9,10,11) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 25.7 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143150
(CHEMBL3759211)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-9-8-22-24-16(9)17(26)23-11-3-5-15(14(21)7-11)25-18(27)12-4-2-10(20)6-13(12)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 851 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143156
(CHEMBL3759990)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-24-8-7-22-16(24)17(26)23-10-5-6-14(13(21)9-10)25-18(27)11-3-2-4-12(20)15(11)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143164
(CHEMBL3758216)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O3S/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(21)7-11)24-18(26)12-4-2-10(20)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 51 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143145
(CHEMBL3759381)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O4/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(20)7-11)24-18(26)12-4-2-10(21)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 141 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143085
(CHEMBL3759846)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H12ClN5O3/c1-9-8-21-23-14(9)16(25)22-10-4-5-13(12(19)7-10)24-17(26)11-3-2-6-20-15(11)18(24)27/h2-8H,1H3,(H,21,23)(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143085
(CHEMBL3759846)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H12ClN5O3/c1-9-8-21-23-14(9)16(25)22-10-4-5-13(12(19)7-10)24-17(26)11-3-2-6-20-15(11)18(24)27/h2-8H,1H3,(H,21,23)(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143167
(CHEMBL3758617)Show SMILES CN1CCC[C@H]1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 |r| Show InChI InChI=1S/C20H18ClN3O3/c1-23-10-4-7-17(23)18(25)22-12-8-9-16(15(21)11-12)24-19(26)13-5-2-3-6-14(13)20(24)27/h2-3,5-6,8-9,11,17H,4,7,10H2,1H3,(H,22,25)/t17-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143167
(CHEMBL3758617)Show SMILES CN1CCC[C@H]1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 |r| Show InChI InChI=1S/C20H18ClN3O3/c1-23-10-4-7-17(23)18(25)22-12-8-9-16(15(21)11-12)24-19(26)13-5-2-3-6-14(13)20(24)27/h2-3,5-6,8-9,11,17H,4,7,10H2,1H3,(H,22,25)/t17-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143171
(CHEMBL3758683)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClN3O3S/c1-10-16(21-9-27-10)17(24)22-11-6-7-15(14(20)8-11)23-18(25)12-4-2-3-5-13(12)19(23)26/h2-9H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 56 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143177
(CHEMBL3758942)Show SMILES Cn1cccc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3/c1-23-10-4-7-17(23)18(25)22-12-8-9-16(15(21)11-12)24-19(26)13-5-2-3-6-14(13)20(24)27/h2-11H,1H3,(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.25E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143177
(CHEMBL3758942)Show SMILES Cn1cccc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3/c1-23-10-4-7-17(23)18(25)22-12-8-9-16(15(21)11-12)24-19(26)13-5-2-3-6-14(13)20(24)27/h2-11H,1H3,(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.26E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143062
(CHEMBL3758435)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(F)cc2C1=O Show InChI InChI=1S/C11H10BrN3O/c1-15-10(16)8(12)9(14-11(15)13)7-5-3-2-4-6-7/h2-6H,1H3,(H2,13,14) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.93E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143164
(CHEMBL3758216)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O3S/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(21)7-11)24-18(26)12-4-2-10(20)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.98E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143161
(CHEMBL3759171)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O3S/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(12(20)7-10)24-18(26)11-3-2-4-13(21)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 474 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143158
(CHEMBL3758228)Show SMILES Cc1cccc2C(=O)N(C(=O)c12)c1ccc(NC(=O)c2nccn2C)cc1Cl Show InChI InChI=1S/C20H15ClN4O3/c1-11-4-3-5-13-16(11)20(28)25(19(13)27)15-7-6-12(10-14(15)21)23-18(26)17-22-8-9-24(17)2/h3-10H,1-2H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 506 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143076
(CHEMBL3758587)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(C)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O4/c1-10-3-5-13-14(7-10)20(27)24(19(13)26)16-6-4-12(8-15(16)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 198 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143147
(CHEMBL3759705)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H11ClN4O4/c1-9-14(21-8-27-9)16(24)22-10-4-5-13(12(19)7-10)23-17(25)11-3-2-6-20-15(11)18(23)26/h2-8H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.53E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50143062
(CHEMBL3758435)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(F)cc2C1=O Show InChI InChI=1S/C11H10BrN3O/c1-15-10(16)8(12)9(14-11(15)13)7-5-3-2-4-6-7/h2-6H,1H3,(H2,13,14) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu5 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 11.5 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143148
(CHEMBL3759376)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-9-8-22-24-16(9)17(26)23-11-3-5-15(14(20)7-11)25-18(27)12-4-2-10(21)6-13(12)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 632 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143154
(CHEMBL3758795)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-24-8-7-22-16(24)17(26)23-10-5-6-14(12(20)9-10)25-18(27)11-3-2-4-13(21)15(11)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143156
(CHEMBL3759990)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-24-8-7-22-16(24)17(26)23-10-5-6-14(13(21)9-10)25-18(27)11-3-2-4-12(20)15(11)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143157
(CHEMBL3759647)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-24-7-6-22-16(24)17(26)23-11-3-5-15(14(21)9-11)25-18(27)12-4-2-10(20)8-13(12)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 263 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143161
(CHEMBL3759171)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O3S/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(12(20)7-10)24-18(26)11-3-2-4-13(21)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 186 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143162
(CHEMBL3758967)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O3S/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(20)7-11)24-18(26)12-4-2-10(21)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 63 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143162
(CHEMBL3758967)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O3S/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(20)7-11)24-18(26)12-4-2-10(21)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 63 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143147
(CHEMBL3759705)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H11ClN4O4/c1-9-14(21-8-27-9)16(24)22-10-4-5-13(12(19)7-10)23-17(25)11-3-2-6-20-15(11)18(23)26/h2-8H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143146
(CHEMBL3759878)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O4/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(12(20)7-10)24-18(26)11-3-2-4-13(21)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143081
(CHEMBL3759028)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-9-8-22-24-16(9)17(26)23-10-5-6-14(12(20)7-10)25-18(27)11-3-2-4-13(21)15(11)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 22.4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143171
(CHEMBL3758683)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClN3O3S/c1-10-16(21-9-27-10)17(24)22-11-6-7-15(14(20)8-11)23-18(25)12-4-2-3-5-13(12)19(23)26/h2-9H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 59 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143174
(CHEMBL3760031)Show SMILES Cc1ncoc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClN3O4/c1-10-16(27-9-21-10)17(24)22-11-6-7-15(14(20)8-11)23-18(25)12-4-2-3-5-13(12)19(23)26/h2-9H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143174
(CHEMBL3760031)Show SMILES Cc1ncoc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClN3O4/c1-10-16(27-9-21-10)17(24)22-11-6-7-15(14(20)8-11)23-18(25)12-4-2-3-5-13(12)19(23)26/h2-9H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143178
(CHEMBL3759994)Show SMILES Cc1[nH]ccc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3/c1-11-13(8-9-22-11)18(25)23-12-6-7-17(16(21)10-12)24-19(26)14-4-2-3-5-15(14)20(24)27/h2-10,22H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143179
(CHEMBL3760068)Show SMILES Cc1cc[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3/c1-11-8-9-22-17(11)18(25)23-12-6-7-16(15(21)10-12)24-19(26)13-4-2-3-5-14(13)20(24)27/h2-10,22H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.42E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143149
(CHEMBL3758298)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-9-8-22-24-16(9)17(26)23-10-5-6-14(13(21)7-10)25-18(27)11-3-2-4-12(20)15(11)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143144
(CHEMBL3759867)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O4/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(13(21)7-10)24-18(26)11-3-2-4-12(20)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 983 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143165
(CHEMBL3760018)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3S/c1-10-4-3-5-13-16(10)20(27)24(19(13)26)15-7-6-12(8-14(15)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 229 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143086
(CHEMBL3759289)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O4/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(21)7-11)24-18(26)12-4-2-10(20)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 54 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143175
(CHEMBL3759354)Show SMILES Cc1sccc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H13ClN2O3S/c1-11-13(8-9-27-11)18(24)22-12-6-7-17(16(21)10-12)23-19(25)14-4-2-3-5-15(14)20(23)26/h2-10H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143176
(CHEMBL3759137)Show SMILES Cc1ccsc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H13ClN2O3S/c1-11-8-9-27-17(11)18(24)22-12-6-7-16(15(21)10-12)23-19(25)13-4-2-3-5-14(13)20(23)26/h2-10H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.89E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143061
(CHEMBL3759901)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(Cl)cc2C1=O Show InChI InChI=1S/C11H8N6O3/c12-11-13-8-7(9(18)14-11)15-17(16-8)6-3-1-2-5(4-6)10(19)20/h1-4H,(H,19,20)(H3,12,13,14,16,18) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143162
(CHEMBL3758967)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O3S/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(20)7-11)24-18(26)12-4-2-10(21)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 306 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143150
(CHEMBL3759211)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-9-8-22-24-16(9)17(26)23-11-3-5-15(14(21)7-11)25-18(27)12-4-2-10(20)6-13(12)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.38E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143148
(CHEMBL3759376)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-9-8-22-24-16(9)17(26)23-11-3-5-15(14(20)7-11)25-18(27)12-4-2-10(21)6-13(12)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143083
(CHEMBL3759424)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O4/c1-10-4-3-5-13-16(10)20(27)24(19(13)26)15-7-6-12(8-14(15)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 519 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143146
(CHEMBL3759878)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O4/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(12(20)7-10)24-18(26)11-3-2-4-13(21)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143150
(CHEMBL3759211)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-9-8-22-24-16(9)17(26)23-11-3-5-15(14(21)7-11)25-18(27)12-4-2-10(20)6-13(12)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 855 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143153
(CHEMBL3759672)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H12ClN5O3/c1-23-8-7-21-15(23)16(25)22-10-4-5-13(12(19)9-10)24-17(26)11-3-2-6-20-14(11)18(24)27/h2-9H,1H3,(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143157
(CHEMBL3759647)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-24-7-6-22-16(24)17(26)23-11-3-5-15(14(21)9-11)25-18(27)12-4-2-10(20)8-13(12)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 265 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143163
(CHEMBL3758756)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O3S/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(13(21)7-10)24-18(26)11-3-2-4-12(20)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.37E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143086
(CHEMBL3759289)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O4/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(21)7-11)24-18(26)12-4-2-10(20)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143083
(CHEMBL3759424)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O4/c1-10-4-3-5-13-16(10)20(27)24(19(13)26)15-7-6-12(8-14(15)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 479 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143081
(CHEMBL3759028)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-9-8-22-24-16(9)17(26)23-10-5-6-14(12(20)7-10)25-18(27)11-3-2-4-13(21)15(11)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143168
(CHEMBL3759973)Show SMILES CN1CCC[C@@H]1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 |r| Show InChI InChI=1S/C20H18ClN3O3/c1-23-10-4-7-17(23)18(25)22-12-8-9-16(15(21)11-12)24-19(26)13-5-2-3-6-14(13)20(24)27/h2-3,5-6,8-9,11,17H,4,7,10H2,1H3,(H,22,25)/t17-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143172
(CHEMBL3759658)Show SMILES Cc1ncsc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClN3O3S/c1-10-16(27-9-21-10)17(24)22-11-6-7-15(14(20)8-11)23-18(25)12-4-2-3-5-13(12)19(23)26/h2-9H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143173
(CHEMBL3759321)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClN3O4/c1-10-16(21-9-27-10)17(24)22-11-6-7-15(14(20)8-11)23-18(25)12-4-2-3-5-13(12)19(23)26/h2-9H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.48E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143159
(CHEMBL3759555)Show SMILES Cc1ccc2C(=O)N(C(=O)c2c1)c1ccc(NC(=O)c2nccn2C)cc1Cl Show InChI InChI=1S/C20H15ClN4O3/c1-11-3-5-13-14(9-11)20(28)25(19(13)27)16-6-4-12(10-15(16)21)23-18(26)17-22-7-8-24(17)2/h3-10H,1-2H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 602 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143156
(CHEMBL3759990)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-24-8-7-22-16(24)17(26)23-10-5-6-14(13(21)9-10)25-18(27)11-3-2-4-12(20)15(11)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143155
(CHEMBL3758986)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-24-7-6-22-16(24)17(26)23-11-3-5-15(14(20)9-11)25-18(27)12-4-2-10(21)8-13(12)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143154
(CHEMBL3758795)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-24-8-7-22-16(24)17(26)23-10-5-6-14(12(20)9-10)25-18(27)11-3-2-4-13(21)15(11)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143151
(CHEMBL3759530)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H15ClN4O3/c1-10-4-3-5-13-16(10)20(28)25(19(13)27)15-7-6-12(8-14(15)21)23-18(26)17-11(2)9-22-24-17/h3-9H,1-2H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143061
(CHEMBL3759901)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(Cl)cc2C1=O Show InChI InChI=1S/C11H8N6O3/c12-11-13-8-7(9(18)14-11)15-17(16-8)6-3-1-2-5(4-6)10(19)20/h1-4H,(H,19,20)(H3,12,13,14,16,18) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143151
(CHEMBL3759530)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H15ClN4O3/c1-10-4-3-5-13-16(10)20(28)25(19(13)27)15-7-6-12(8-14(15)21)23-18(26)17-11(2)9-22-24-17/h3-9H,1-2H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.37E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143152
(CHEMBL3759656)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccc(C)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H15ClN4O3/c1-10-3-5-13-14(7-10)20(28)25(19(13)27)16-6-4-12(8-15(16)21)23-18(26)17-11(2)9-22-24-17/h3-9H,1-2H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 562 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143159
(CHEMBL3759555)Show SMILES Cc1ccc2C(=O)N(C(=O)c2c1)c1ccc(NC(=O)c2nccn2C)cc1Cl Show InChI InChI=1S/C20H15ClN4O3/c1-11-3-5-13-14(9-11)20(28)25(19(13)27)16-6-4-12(10-15(16)21)23-18(26)17-22-7-8-24(17)2/h3-10H,1-2H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143161
(CHEMBL3759171)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O3S/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(12(20)7-10)24-18(26)11-3-2-4-13(21)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 187 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143147
(CHEMBL3759705)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H11ClN4O4/c1-9-14(21-8-27-9)16(24)22-10-4-5-13(12(19)7-10)23-17(25)11-3-2-6-20-15(11)18(23)26/h2-8H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143172
(CHEMBL3759658)Show SMILES Cc1ncsc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClN3O3S/c1-10-16(27-9-21-10)17(24)22-11-6-7-15(14(20)8-11)23-18(25)12-4-2-3-5-13(12)19(23)26/h2-9H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143173
(CHEMBL3759321)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClN3O4/c1-10-16(21-9-27-10)17(24)22-11-6-7-15(14(20)8-11)23-18(25)12-4-2-3-5-13(12)19(23)26/h2-9H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143062
(CHEMBL3758435)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(F)cc2C1=O Show InChI InChI=1S/C11H10BrN3O/c1-15-10(16)8(12)9(14-11(15)13)7-5-3-2-4-6-7/h2-6H,1H3,(H2,13,14) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.93E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143163
(CHEMBL3758756)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O3S/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(13(21)7-10)24-18(26)11-3-2-4-12(20)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143085
(CHEMBL3759846)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H12ClN5O3/c1-9-8-21-23-14(9)16(25)22-10-4-5-13(12(19)7-10)24-17(26)11-3-2-6-20-15(11)18(24)27/h2-8H,1H3,(H,21,23)(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143060
(CHEMBL3758305)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(C)c2C1=O Show InChI InChI=1S/C7H9N3O3/c1-2-13-6(12)4-3-9-7(8)10-5(4)11/h3H,2H2,1H3,(H3,8,9,10,11) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143148
(CHEMBL3759376)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-9-8-22-24-16(9)17(26)23-11-3-5-15(14(20)7-11)25-18(27)12-4-2-10(21)6-13(12)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 631 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143149
(CHEMBL3758298)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-9-8-22-24-16(9)17(26)23-10-5-6-14(13(21)7-10)25-18(27)11-3-2-4-12(20)15(11)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143149
(CHEMBL3758298)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-9-8-22-24-16(9)17(26)23-10-5-6-14(13(21)7-10)25-18(27)11-3-2-4-12(20)15(11)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143151
(CHEMBL3759530)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H15ClN4O3/c1-10-4-3-5-13-16(10)20(28)25(19(13)27)15-7-6-12(8-14(15)21)23-18(26)17-11(2)9-22-24-17/h3-9H,1-2H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.36E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143154
(CHEMBL3758795)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-24-8-7-22-16(24)17(26)23-10-5-6-14(12(20)9-10)25-18(27)11-3-2-4-13(21)15(11)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143159
(CHEMBL3759555)Show SMILES Cc1ccc2C(=O)N(C(=O)c2c1)c1ccc(NC(=O)c2nccn2C)cc1Cl Show InChI InChI=1S/C20H15ClN4O3/c1-11-3-5-13-14(9-11)20(28)25(19(13)27)16-6-4-12(10-15(16)21)23-18(26)17-22-7-8-24(17)2/h3-10H,1-2H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 254 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143165
(CHEMBL3760018)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3S/c1-10-4-3-5-13-16(10)20(27)24(19(13)26)15-7-6-12(8-14(15)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 232 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143144
(CHEMBL3759867)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O4/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(13(21)7-10)24-18(26)11-3-2-4-12(20)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143168
(CHEMBL3759973)Show SMILES CN1CCC[C@@H]1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 |r| Show InChI InChI=1S/C20H18ClN3O3/c1-23-10-4-7-17(23)18(25)22-12-8-9-16(15(21)11-12)24-19(26)13-5-2-3-6-14(13)20(24)27/h2-3,5-6,8-9,11,17H,4,7,10H2,1H3,(H,22,25)/t17-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143169
(CHEMBL3759563)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H13ClN4O3/c1-10-9-21-23-16(10)17(25)22-11-6-7-15(14(20)8-11)24-18(26)12-4-2-3-5-13(12)19(24)27/h2-9H,1H3,(H,21,23)(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.24E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143170
(CHEMBL3758364)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H13ClN4O3/c1-23-9-8-21-16(23)17(25)22-11-6-7-15(14(20)10-11)24-18(26)12-4-2-3-5-13(12)19(24)27/h2-10H,1H3,(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 374 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143175
(CHEMBL3759354)Show SMILES Cc1sccc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H13ClN2O3S/c1-11-13(8-9-27-11)18(24)22-12-6-7-17(16(21)10-12)23-19(25)14-4-2-3-5-15(14)20(23)26/h2-10H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143166
(CHEMBL3759038)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccc(C)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3S/c1-10-3-5-13-14(7-10)20(27)24(19(13)26)16-6-4-12(8-15(16)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.12E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143165
(CHEMBL3760018)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3S/c1-10-4-3-5-13-16(10)20(27)24(19(13)26)15-7-6-12(8-14(15)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.41E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143081
(CHEMBL3759028)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-9-8-22-24-16(9)17(26)23-10-5-6-14(12(20)7-10)25-18(27)11-3-2-4-13(21)15(11)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143145
(CHEMBL3759381)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O4/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(20)7-11)24-18(26)12-4-2-10(21)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 642 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu5 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143152
(CHEMBL3759656)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccc(C)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H15ClN4O3/c1-10-3-5-13-14(7-10)20(28)25(19(13)27)16-6-4-12(8-15(16)21)23-18(26)17-11(2)9-22-24-17/h3-9H,1-2H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 557 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143153
(CHEMBL3759672)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H12ClN5O3/c1-23-8-7-21-15(23)16(25)22-10-4-5-13(12(19)9-10)24-17(26)11-3-2-6-20-14(11)18(24)27/h2-9H,1H3,(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143155
(CHEMBL3758986)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-24-7-6-22-16(24)17(26)23-11-3-5-15(14(20)9-11)25-18(27)12-4-2-10(21)8-13(12)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 673 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143158
(CHEMBL3758228)Show SMILES Cc1cccc2C(=O)N(C(=O)c12)c1ccc(NC(=O)c2nccn2C)cc1Cl Show InChI InChI=1S/C20H15ClN4O3/c1-11-4-3-5-13-16(11)20(28)25(19(13)27)15-7-6-12(10-14(15)21)23-18(26)17-22-8-9-24(17)2/h3-10H,1-2H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143166
(CHEMBL3759038)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccc(C)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3S/c1-10-3-5-13-14(7-10)20(27)24(19(13)26)16-6-4-12(8-15(16)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143146
(CHEMBL3759878)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O4/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(12(20)7-10)24-18(26)11-3-2-4-13(21)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.69E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143145
(CHEMBL3759381)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O4/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(20)7-11)24-18(26)12-4-2-10(21)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 141 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143144
(CHEMBL3759867)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O4/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(13(21)7-10)24-18(26)11-3-2-4-12(20)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.29E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143083
(CHEMBL3759424)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O4/c1-10-4-3-5-13-16(10)20(27)24(19(13)26)15-7-6-12(8-14(15)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 469 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143076
(CHEMBL3758587)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(C)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O4/c1-10-3-5-13-14(7-10)20(27)24(19(13)26)16-6-4-12(8-15(16)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 42 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143169
(CHEMBL3759563)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H13ClN4O3/c1-10-9-21-23-16(10)17(25)22-11-6-7-15(14(20)8-11)24-18(26)12-4-2-3-5-13(12)19(24)27/h2-9H,1H3,(H,21,23)(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143179
(CHEMBL3760068)Show SMILES Cc1cc[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3/c1-11-8-9-22-17(11)18(25)23-12-6-7-16(15(21)10-12)24-19(26)13-4-2-3-5-14(13)20(24)27/h2-10,22H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.47E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143063
(CHEMBL3758465)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(F)c2C1=O Show InChI InChI=1S/C20H13F6N7O2/c21-19(22,23)11-4-9(5-12(7-11)20(24,25)26)8-28-16(34)10-2-1-3-13(6-10)33-31-14-15(32-33)29-18(27)30-17(14)35/h1-7H,8H2,(H,28,34)(H3,27,29,30,32,35) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143063
(CHEMBL3758465)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2cccc(F)c2C1=O Show InChI InChI=1S/C20H13F6N7O2/c21-19(22,23)11-4-9(5-12(7-11)20(24,25)26)8-28-16(34)10-2-1-3-13(6-10)33-31-14-15(32-33)29-18(27)30-17(14)35/h1-7H,8H2,(H,28,34)(H3,27,29,30,32,35) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143160
(CHEMBL3759573)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H11ClN4O3S/c1-9-14(21-8-27-9)16(24)22-10-4-5-13(12(19)7-10)23-17(25)11-3-2-6-20-15(11)18(23)26/h2-8H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143153
(CHEMBL3759672)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H12ClN5O3/c1-23-8-7-21-15(23)16(25)22-10-4-5-13(12(19)9-10)24-17(26)11-3-2-6-20-14(11)18(24)27/h2-9H,1H3,(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Search and Browse
