Affinity Data by PubMed id=26784936

PubMed code 26784936

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sterol regulatory element-binding protein 2 (Homo sapiens (Human))	BDBM50159362 (CHEMBL3785912) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Catabasis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of SREBP2 in human HepG2 cells assessed as reduction of PCSK9 secretion after 16 hrs by ELISA				J Med Chem 59: 1217-31 (2016) Article DOI: 10.1021/acs.jmedchem.5b01961 BindingDB Entry DOI: 10.7270/Q2G162QT
Catabasis Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM23515 (CHEMBL573 \| Niacin \| Nicotinic Acid \| [5, 6-3H]-ni...) Show SMILES OC(=O)c1cccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	730	n/a	n/a	n/a	n/a
Catabasis Pharmaceuticals Curated by ChEMBL					Assay Description Activation of GPR109A in human A431 cells assessed as suppression of forskolin-induced cAMP production after 30 mins				J Med Chem 59: 1217-31 (2016) Article DOI: 10.1021/acs.jmedchem.5b01961 BindingDB Entry DOI: 10.7270/Q2G162QT
Catabasis Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%