Found 60 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500711
(CHEMBL3752378)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc2CSc3cc(Cl)ccc3-c2n1 Show InChI InChI=1S/C16H12ClN3O2S2/c17-11-1-6-14-15(7-11)23-9-10-8-20(19-16(10)14)12-2-4-13(5-3-12)24(18,21)22/h1-8H,9H2,(H2,18,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500710
(CHEMBL3753927)Show InChI InChI=1S/C16H14N4O2S/c17-23(21,22)13-7-5-12(6-8-13)20-10-11-9-18-15-4-2-1-3-14(15)16(11)19-20/h1-8,10,18H,9H2,(H2,17,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500699
(CHEMBL3753359)Show InChI InChI=1S/C17H14N4O2S2/c18-25(22,23)13-7-5-12(6-8-13)20-17-19-9-11-10-24-15-4-2-1-3-14(15)16(11)21-17/h1-9H,10H2,(H2,18,22,23)(H,19,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500710
(CHEMBL3753927)Show InChI InChI=1S/C16H14N4O2S/c17-23(21,22)13-7-5-12(6-8-13)20-10-11-9-18-15-4-2-1-3-14(15)16(11)19-20/h1-8,10,18H,9H2,(H2,17,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500698
(CHEMBL3751874)Show SMILES COc1ccc2-c3nn(cc3CSc2c1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H15N3O3S2/c1-23-13-4-7-15-16(8-13)24-10-11-9-20(19-17(11)15)12-2-5-14(6-3-12)25(18,21)22/h2-9H,10H2,1H3,(H2,18,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500698
(CHEMBL3751874)Show SMILES COc1ccc2-c3nn(cc3CSc2c1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H15N3O3S2/c1-23-13-4-7-15-16(8-13)24-10-11-9-20(19-17(11)15)12-2-5-14(6-3-12)25(18,21)22/h2-9H,10H2,1H3,(H2,18,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500702
(CHEMBL3752602)Show SMILES Cc1ccc2-c3nn(cc3CNc2c1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H16N4O2S/c1-11-2-7-15-16(8-11)19-9-12-10-21(20-17(12)15)13-3-5-14(6-4-13)24(18,22)23/h2-8,10,19H,9H2,1H3,(H2,18,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500702
(CHEMBL3752602)Show SMILES Cc1ccc2-c3nn(cc3CNc2c1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H16N4O2S/c1-11-2-7-15-16(8-11)19-9-12-10-21(20-17(12)15)13-3-5-14(6-4-13)24(18,22)23/h2-8,10,19H,9H2,1H3,(H2,18,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500700
(CHEMBL3752481)Show SMILES Cc1ccc-2c(SCc3cnc(Nc4ccc(cc4)S(N)(=O)=O)nc-23)n1 Show InChI InChI=1S/C17H15N5O2S2/c1-10-2-7-14-15-11(9-25-16(14)20-10)8-19-17(22-15)21-12-3-5-13(6-4-12)26(18,23)24/h2-8H,9H2,1H3,(H2,18,23,24)(H,19,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500700
(CHEMBL3752481)Show SMILES Cc1ccc-2c(SCc3cnc(Nc4ccc(cc4)S(N)(=O)=O)nc-23)n1 Show InChI InChI=1S/C17H15N5O2S2/c1-10-2-7-14-15-11(9-25-16(14)20-10)8-19-17(22-15)21-12-3-5-13(6-4-12)26(18,23)24/h2-8H,9H2,1H3,(H2,18,23,24)(H,19,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 8.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500711
(CHEMBL3752378)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc2CSc3cc(Cl)ccc3-c2n1 Show InChI InChI=1S/C16H12ClN3O2S2/c17-11-1-6-14-15(7-11)23-9-10-8-20(19-16(10)14)12-2-4-13(5-3-12)24(18,21)22/h1-8H,9H2,(H2,18,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 8.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500703
(CHEMBL3752163)Show SMILES NS(=O)(=O)c1ccc(Nc2ncc3CSc4cc(Cl)ccc4-c3n2)cc1 Show InChI InChI=1S/C17H13ClN4O2S2/c18-11-1-6-14-15(7-11)25-9-10-8-20-17(22-16(10)14)21-12-2-4-13(5-3-12)26(19,23)24/h1-8H,9H2,(H2,19,23,24)(H,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 8.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500708
(CHEMBL3754807)Show InChI InChI=1S/C16H13N5O2S2/c17-25(22,23)12-5-3-11(4-6-12)20-16-19-8-10-9-24-15-13(14(10)21-16)2-1-7-18-15/h1-8H,9H2,(H2,17,22,23)(H,19,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
MMDB
PDB
Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500703
(CHEMBL3752163)Show SMILES NS(=O)(=O)c1ccc(Nc2ncc3CSc4cc(Cl)ccc4-c3n2)cc1 Show InChI InChI=1S/C17H13ClN4O2S2/c18-11-1-6-14-15(7-11)25-9-10-8-20-17(22-16(10)14)21-12-2-4-13(5-3-12)26(19,23)24/h1-8H,9H2,(H2,19,23,24)(H,20,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500708
(CHEMBL3754807)Show InChI InChI=1S/C16H13N5O2S2/c17-25(22,23)12-5-3-11(4-6-12)20-16-19-8-10-9-24-15-13(14(10)21-16)2-1-7-18-15/h1-8H,9H2,(H2,17,22,23)(H,19,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500706
(CHEMBL3752794)Show SMILES COc1ccc-2c(SCc3cnc(Nc4ccc(cc4)S(N)(=O)=O)nc-23)c1 Show InChI InChI=1S/C18H16N4O3S2/c1-25-13-4-7-15-16(8-13)26-10-11-9-20-18(22-17(11)15)21-12-2-5-14(6-3-12)27(19,23)24/h2-9H,10H2,1H3,(H2,19,23,24)(H,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500710
(CHEMBL3753927)Show InChI InChI=1S/C16H14N4O2S/c17-23(21,22)13-7-5-12(6-8-13)20-10-11-9-18-15-4-2-1-3-14(15)16(11)19-20/h1-8,10,18H,9H2,(H2,17,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500708
(CHEMBL3754807)Show InChI InChI=1S/C16H13N5O2S2/c17-25(22,23)12-5-3-11(4-6-12)20-16-19-8-10-9-24-15-13(14(10)21-16)2-1-7-18-15/h1-8H,9H2,(H2,17,22,23)(H,19,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500700
(CHEMBL3752481)Show SMILES Cc1ccc-2c(SCc3cnc(Nc4ccc(cc4)S(N)(=O)=O)nc-23)n1 Show InChI InChI=1S/C17H15N5O2S2/c1-10-2-7-14-15-11(9-25-16(14)20-10)8-19-17(22-15)21-12-3-5-13(6-4-12)26(18,23)24/h2-8H,9H2,1H3,(H2,18,23,24)(H,19,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500702
(CHEMBL3752602)Show SMILES Cc1ccc2-c3nn(cc3CNc2c1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H16N4O2S/c1-11-2-7-15-16(8-11)19-9-12-10-21(20-17(12)15)13-3-5-14(6-4-13)24(18,22)23/h2-8,10,19H,9H2,1H3,(H2,18,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500698
(CHEMBL3751874)Show SMILES COc1ccc2-c3nn(cc3CSc2c1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H15N3O3S2/c1-23-13-4-7-15-16(8-13)24-10-11-9-20(19-17(11)15)12-2-5-14(6-3-12)25(18,21)22/h2-9H,10H2,1H3,(H2,18,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500707
(CHEMBL3752864)Show InChI InChI=1S/C17H17NO3S/c1-18(9-17(19)20)12-4-3-11-10-22-16-8-13(21-2)5-6-14(16)15(11)7-12/h3-8H,9-10H2,1-2H3,(H,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500711
(CHEMBL3752378)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc2CSc3cc(Cl)ccc3-c2n1 Show InChI InChI=1S/C16H12ClN3O2S2/c17-11-1-6-14-15(7-11)23-9-10-8-20(19-16(10)14)12-2-4-13(5-3-12)24(18,21)22/h1-8H,9H2,(H2,18,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500706
(CHEMBL3752794)Show SMILES COc1ccc-2c(SCc3cnc(Nc4ccc(cc4)S(N)(=O)=O)nc-23)c1 Show InChI InChI=1S/C18H16N4O3S2/c1-25-13-4-7-15-16(8-13)26-10-11-9-20-18(22-17(11)15)21-12-2-5-14(6-3-12)27(19,23)24/h2-9H,10H2,1H3,(H2,19,23,24)(H,20,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500704
(CHEMBL3753865)Show InChI InChI=1S/C16H15NO3S/c1-20-12-4-5-13-14-6-11(17-8-16(18)19)3-2-10(14)9-21-15(13)7-12/h2-7,17H,8-9H2,1H3,(H,18,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500702
(CHEMBL3752602)Show SMILES Cc1ccc2-c3nn(cc3CNc2c1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H16N4O2S/c1-11-2-7-15-16(8-11)19-9-12-10-21(20-17(12)15)13-3-5-14(6-4-13)24(18,22)23/h2-8,10,19H,9H2,1H3,(H2,18,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500706
(CHEMBL3752794)Show SMILES COc1ccc-2c(SCc3cnc(Nc4ccc(cc4)S(N)(=O)=O)nc-23)c1 Show InChI InChI=1S/C18H16N4O3S2/c1-25-13-4-7-15-16(8-13)26-10-11-9-20-18(22-17(11)15)21-12-2-5-14(6-3-12)27(19,23)24/h2-9H,10H2,1H3,(H2,19,23,24)(H,20,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500710
(CHEMBL3753927)Show InChI InChI=1S/C16H14N4O2S/c17-23(21,22)13-7-5-12(6-8-13)20-10-11-9-18-15-4-2-1-3-14(15)16(11)19-20/h1-8,10,18H,9H2,(H2,17,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500706
(CHEMBL3752794)Show SMILES COc1ccc-2c(SCc3cnc(Nc4ccc(cc4)S(N)(=O)=O)nc-23)c1 Show InChI InChI=1S/C18H16N4O3S2/c1-25-13-4-7-15-16(8-13)26-10-11-9-20-18(22-17(11)15)21-12-2-5-14(6-3-12)27(19,23)24/h2-9H,10H2,1H3,(H2,19,23,24)(H,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500698
(CHEMBL3751874)Show SMILES COc1ccc2-c3nn(cc3CSc2c1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H15N3O3S2/c1-23-13-4-7-15-16(8-13)24-10-11-9-20(19-17(11)15)12-2-5-14(6-3-12)25(18,21)22/h2-9H,10H2,1H3,(H2,18,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500708
(CHEMBL3754807)Show InChI InChI=1S/C16H13N5O2S2/c17-25(22,23)12-5-3-11(4-6-12)20-16-19-8-10-9-24-15-13(14(10)21-16)2-1-7-18-15/h1-8H,9H2,(H2,17,22,23)(H,19,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500701
(CHEMBL3752729)Show InChI InChI=1S/C15H14N2O2S/c1-17(8-14(18)19)11-5-4-10-9-20-15-12(13(10)7-11)3-2-6-16-15/h2-7H,8-9H2,1H3,(H,18,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500700
(CHEMBL3752481)Show SMILES Cc1ccc-2c(SCc3cnc(Nc4ccc(cc4)S(N)(=O)=O)nc-23)n1 Show InChI InChI=1S/C17H15N5O2S2/c1-10-2-7-14-15-11(9-25-16(14)20-10)8-19-17(22-15)21-12-3-5-13(6-4-12)26(18,23)24/h2-8H,9H2,1H3,(H2,18,23,24)(H,19,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500711
(CHEMBL3752378)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc2CSc3cc(Cl)ccc3-c2n1 Show InChI InChI=1S/C16H12ClN3O2S2/c17-11-1-6-14-15(7-11)23-9-10-8-20(19-16(10)14)12-2-4-13(5-3-12)24(18,21)22/h1-8H,9H2,(H2,18,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500699
(CHEMBL3753359)Show InChI InChI=1S/C17H14N4O2S2/c18-25(22,23)13-7-5-12(6-8-13)20-17-19-9-11-10-24-15-4-2-1-3-14(15)16(11)21-17/h1-9H,10H2,(H2,18,22,23)(H,19,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500699
(CHEMBL3753359)Show InChI InChI=1S/C17H14N4O2S2/c18-25(22,23)13-7-5-12(6-8-13)20-17-19-9-11-10-24-15-4-2-1-3-14(15)16(11)21-17/h1-9H,10H2,(H2,18,22,23)(H,19,20,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500703
(CHEMBL3752163)Show SMILES NS(=O)(=O)c1ccc(Nc2ncc3CSc4cc(Cl)ccc4-c3n2)cc1 Show InChI InChI=1S/C17H13ClN4O2S2/c18-11-1-6-14-15(7-11)25-9-10-8-20-17(22-16(10)14)21-12-2-4-13(5-3-12)26(19,23)24/h1-8H,9H2,(H2,19,23,24)(H,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500705
(CHEMBL3753066)Show InChI InChI=1S/C16H16N2O2S/c1-10-3-6-13-14-7-12(18(2)8-15(19)20)5-4-11(14)9-21-16(13)17-10/h3-7H,8-9H2,1-2H3,(H,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500699
(CHEMBL3753359)Show InChI InChI=1S/C17H14N4O2S2/c18-25(22,23)13-7-5-12(6-8-13)20-17-19-9-11-10-24-15-4-2-1-3-14(15)16(11)21-17/h1-9H,10H2,(H2,18,22,23)(H,19,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 96 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500703
(CHEMBL3752163)Show SMILES NS(=O)(=O)c1ccc(Nc2ncc3CSc4cc(Cl)ccc4-c3n2)cc1 Show InChI InChI=1S/C17H13ClN4O2S2/c18-11-1-6-14-15(7-11)25-9-10-8-20-17(22-16(10)14)21-12-2-4-13(5-3-12)26(19,23)24/h1-8H,9H2,(H2,19,23,24)(H,20,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 218 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
PDB
Article
PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50500709
(CHEMBL3753610)Show SMILES COc1ccc-2c(SCc3ccc(NCC[C@H](N)C(O)=O)cc-23)c1 |r| Show InChI InChI=1S/C18H20N2O3S/c1-23-13-4-5-14-15-8-12(20-7-6-16(19)18(21)22)3-2-11(15)10-24-17(14)9-13/h2-5,8-9,16,20H,6-7,10,19H2,1H3,(H,21,22)/t16-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 335 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500705
(CHEMBL3753066)Show InChI InChI=1S/C16H16N2O2S/c1-10-3-6-13-14-7-12(18(2)8-15(19)20)5-4-11(14)9-21-16(13)17-10/h3-7H,8-9H2,1-2H3,(H,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500701
(CHEMBL3752729)Show InChI InChI=1S/C15H14N2O2S/c1-17(8-14(18)19)11-5-4-10-9-20-15-12(13(10)7-11)3-2-6-16-15/h2-7H,8-9H2,1H3,(H,18,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500707
(CHEMBL3752864)Show InChI InChI=1S/C17H17NO3S/c1-18(9-17(19)20)12-4-3-11-10-22-16-8-13(21-2)5-6-14(16)15(11)7-12/h3-8H,9-10H2,1-2H3,(H,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500701
(CHEMBL3752729)Show InChI InChI=1S/C15H14N2O2S/c1-17(8-14(18)19)11-5-4-10-9-20-15-12(13(10)7-11)3-2-6-16-15/h2-7H,8-9H2,1H3,(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 638 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500704
(CHEMBL3753865)Show InChI InChI=1S/C16H15NO3S/c1-20-12-4-5-13-14-6-11(17-8-16(18)19)3-2-10(14)9-21-15(13)7-12/h2-7,17H,8-9H2,1H3,(H,18,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 871 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500704
(CHEMBL3753865)Show InChI InChI=1S/C16H15NO3S/c1-20-12-4-5-13-14-6-11(17-8-16(18)19)3-2-10(14)9-21-15(13)7-12/h2-7,17H,8-9H2,1H3,(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 4.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500707
(CHEMBL3752864)Show InChI InChI=1S/C17H17NO3S/c1-18(9-17(19)20)12-4-3-11-10-22-16-8-13(21-2)5-6-14(16)15(11)7-12/h3-8H,9-10H2,1-2H3,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 5.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500704
(CHEMBL3753865)Show InChI InChI=1S/C16H15NO3S/c1-20-12-4-5-13-14-6-11(17-8-16(18)19)3-2-10(14)9-21-15(13)7-12/h2-7,17H,8-9H2,1H3,(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 5.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500705
(CHEMBL3753066)Show InChI InChI=1S/C16H16N2O2S/c1-10-3-6-13-14-7-12(18(2)8-15(19)20)5-4-11(14)9-21-16(13)17-10/h3-7H,8-9H2,1-2H3,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500701
(CHEMBL3752729)Show InChI InChI=1S/C15H14N2O2S/c1-17(8-14(18)19)11-5-4-10-9-20-15-12(13(10)7-11)3-2-6-16-15/h2-7H,8-9H2,1H3,(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500705
(CHEMBL3753066)Show InChI InChI=1S/C16H16N2O2S/c1-10-3-6-13-14-7-12(18(2)8-15(19)20)5-4-11(14)9-21-16(13)17-10/h3-7H,8-9H2,1-2H3,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500707
(CHEMBL3752864)Show InChI InChI=1S/C17H17NO3S/c1-18(9-17(19)20)12-4-3-11-10-22-16-8-13(21-2)5-6-14(16)15(11)7-12/h3-8H,9-10H2,1-2H3,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 8.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50500709
(CHEMBL3753610)Show SMILES COc1ccc-2c(SCc3ccc(NCC[C@H](N)C(O)=O)cc-23)c1 |r| Show InChI InChI=1S/C18H20N2O3S/c1-23-13-4-5-14-15-8-12(20-7-6-16(19)18(21)22)3-2-11(15)10-24-17(14)9-13/h2-5,8-9,16,20H,6-7,10,19H2,1H3,(H,21,22)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 9.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50500709
(CHEMBL3753610)Show SMILES COc1ccc-2c(SCc3ccc(NCC[C@H](N)C(O)=O)cc-23)c1 |r| Show InChI InChI=1S/C18H20N2O3S/c1-23-13-4-5-14-15-8-12(20-7-6-16(19)18(21)22)3-2-11(15)10-24-17(14)9-13/h2-5,8-9,16,20H,6-7,10,19H2,1H3,(H,21,22)/t16-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50500709
(CHEMBL3753610)Show SMILES COc1ccc-2c(SCc3ccc(NCC[C@H](N)C(O)=O)cc-23)c1 |r| Show InChI InChI=1S/C18H20N2O3S/c1-23-13-4-5-14-15-8-12(20-7-6-16(19)18(21)22)3-2-11(15)10-24-17(14)9-13/h2-5,8-9,16,20H,6-7,10,19H2,1H3,(H,21,22)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 24: 921-7 (2016)
Article DOI: 10.1016/j.bmc.2016.01.018
BindingDB Entry DOI: 10.7270/Q2000531 |
More data for this
Ligand-Target Pair | |
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