Affinity Data by PubMed id=26869193

PubMed code 26869193

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine \| 1,2,3,4-tetrah...) Show SMILES Nc1c2CCCCc2nc2ccccc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 26: 1624-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.080 BindingDB Entry DOI: 10.7270/Q2W66NND
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM11682 (2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...) Show SMILES CCN(C)C(=O)Oc1cccc(c1)[C@H](C)N(C)C \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 26: 1624-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.080 BindingDB Entry DOI: 10.7270/Q2W66NND
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50158402 (CHEMBL3781198) Show SMILES CN(C)C(=O)Oc1c(C)n(ccc1=O)-c1ccccc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibition of electric eel AChE preincubated for 5 mins followed by addition of acetylthiocholine iodide measured after 2 mins by Ellman's method				Bioorg Med Chem Lett 26: 1624-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.080 BindingDB Entry DOI: 10.7270/Q2W66NND
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50158534 (CHEMBL3781763) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 26: 1624-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.080 BindingDB Entry DOI: 10.7270/Q2W66NND
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50086229 (CHEMBL326815) Show SMILES Cc1c(O)c(=O)ccn1-c1ccccc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 26: 1624-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.080 BindingDB Entry DOI: 10.7270/Q2W66NND
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50158537 (CHEMBL3781438) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.52E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 26: 1624-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.080 BindingDB Entry DOI: 10.7270/Q2W66NND
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50158538 (CHEMBL3780941) Show SMILES CN(C)C(=O)Oc1ccc(cc1)-n1ccc(=O)c(O)c1C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.48E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 26: 1624-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.080 BindingDB Entry DOI: 10.7270/Q2W66NND
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50158403 (P-TOLYL DIMETHYLCARBAMATE) Show SMILES CN(C)C(=O)Oc1ccc(C)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's method				Bioorg Med Chem Lett 26: 1624-8 (2016) Article DOI: 10.1016/j.bmcl.2016.01.080 BindingDB Entry DOI: 10.7270/Q2W66NND
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%