Affinity Data by PubMed id=26905390

PubMed code 26905390

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50284267 (Boropinal) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Activation of human TRPA1 expressed in HEK293 cells assessed as increase in calcium level by fluo-4 dye based plate reader analysis				J Nat Prod 79: 697-703 (2016) Article DOI: 10.1021/acs.jnatprod.5b00396 BindingDB Entry DOI: 10.7270/Q2WQ078D
Universit£t Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM24777 (5-hydroxy-1,4-dihydronaphthalene-1,4-dione \| 5-hyd...) Show SMILES Oc1cccc2C(=O)C=CC(=O)c12 \|c:8\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Activation of human TRPA1 expressed in HEK293 cells assessed as increase in calcium level by fluo-4 dye based plate reader analysis				J Nat Prod 79: 697-703 (2016) Article DOI: 10.1021/acs.jnatprod.5b00396 BindingDB Entry DOI: 10.7270/Q2WQ078D
Universit£t Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50203072 (3-isothiocyanatoprop-1-ene \| Allyl isothiocyanate ...) Show SMILES C=CCN=C=S Show InChI InChI=1S/C4H5NS/c1-2-3-5-4-6/h2H,1,3H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Activation of human TRPA1 expressed in HEK293 cells assessed as increase in calcium level by fluo-4 dye based plate reader analysis				J Nat Prod 79: 697-703 (2016) Article DOI: 10.1021/acs.jnatprod.5b00396 BindingDB Entry DOI: 10.7270/Q2WQ078D
Universit£t Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50012070 (5-Hydroxy-2-methyl-[1,4]naphthoquinone \| 5-hydroxy...) Show SMILES CC1=CC(=O)c2c(O)cccc2C1=O \|t:1\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	460	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Activation of human TRPA1 expressed in HEK293 cells assessed as increase in calcium level by fluo-4 dye based plate reader analysis				J Nat Prod 79: 697-703 (2016) Article DOI: 10.1021/acs.jnatprod.5b00396 BindingDB Entry DOI: 10.7270/Q2WQ078D
Universit£t Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM24777 (5-hydroxy-1,4-dihydronaphthalene-1,4-dione \| 5-hyd...) Show SMILES Oc1cccc2C(=O)C=CC(=O)c12 \|c:8\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Activation of human TRPA1 expressed in HEK293 cells assessed as increase in calcium level by fluo-4 dye based plate reader analysis				J Nat Prod 79: 697-703 (2016) Article DOI: 10.1021/acs.jnatprod.5b00396 BindingDB Entry DOI: 10.7270/Q2WQ078D
Universit£t Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50203072 (3-isothiocyanatoprop-1-ene \| Allyl isothiocyanate ...) Show SMILES C=CCN=C=S Show InChI InChI=1S/C4H5NS/c1-2-3-5-4-6/h2H,1,3H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Activation of human TRPA1 expressed in HEK293 cells assessed as increase in calcium level by fluo-4 dye based plate reader analysis				J Nat Prod 79: 697-703 (2016) Article DOI: 10.1021/acs.jnatprod.5b00396 BindingDB Entry DOI: 10.7270/Q2WQ078D
Universit£t Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50284267 (Boropinal) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Activation of human TRPA1 expressed in HEK293 cells assessed as increase in calcium level by fluo-4 dye based plate reader analysis				J Nat Prod 79: 697-703 (2016) Article DOI: 10.1021/acs.jnatprod.5b00396 BindingDB Entry DOI: 10.7270/Q2WQ078D
Universit£t Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50012070 (5-Hydroxy-2-methyl-[1,4]naphthoquinone \| 5-hydroxy...) Show SMILES CC1=CC(=O)c2c(O)cccc2C1=O \|t:1\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	460	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Activation of human TRPA1 expressed in HEK293 cells assessed as increase in calcium level by fluo-4 dye based plate reader analysis				J Nat Prod 79: 697-703 (2016) Article DOI: 10.1021/acs.jnatprod.5b00396 BindingDB Entry DOI: 10.7270/Q2WQ078D
Universit£t Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%