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PubMed code 26985630

Compile data set for download or QSAR
Found 46 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158355
PNG
(CHEMBL3781822 | US10858316, Compound 3bl)
Show SMILES Cc1cc(Oc2ccc(cc2)N(Cc2ccccc2)S(=O)(=O)c2cc(C(O)=O)c(O)c3ccccc23)cc(C)c1Cl
Show InChI InChI=1S/C32H26ClNO6S/c1-20-16-25(17-21(2)30(20)33)40-24-14-12-23(13-15-24)34(19-22-8-4-3-5-9-22)41(38,39)29-18-28(32(36)37)31(35)27-11-7-6-10-26(27)29/h3-18,35H,19H2,1-2H3,(H,36,37)
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 31n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158354
PNG
(CHEMBL3780397)
Show SMILES Cc1cc(Oc2ccc(cc2)N(C2CCCC2)S(=O)(=O)c2cc(C(O)=O)c(O)c3ccccc23)cc(C)c1Cl
Show InChI InChI=1S/C30H28ClNO6S/c1-18-15-23(16-19(2)28(18)31)38-22-13-11-21(12-14-22)32(20-7-3-4-8-20)39(36,37)27-17-26(30(34)35)29(33)25-10-6-5-9-24(25)27/h5-6,9-17,20,33H,3-4,7-8H2,1-2H3,(H,34,35)
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 33n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158326
PNG
(CHEMBL3781669 | US10858316, Compound 3bg)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc(Oc2ccc(Cl)cc2Cl)cc1
Show InChI InChI=1S/C23H15Cl2NO6S/c24-13-5-10-20(19(25)11-13)32-15-8-6-14(7-9-15)26-33(30,31)21-12-18(23(28)29)22(27)17-4-2-1-3-16(17)21/h1-12,26-27H,(H,28,29)
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 79n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158353
PNG
(CHEMBL3780803 | US10858316, Compound 3bj)
Show SMILES CC(C)CN(c1ccc(Oc2cc(C)c(Cl)c(C)c2)cc1)S(=O)(=O)c1cc(C(O)=O)c(O)c2ccccc12
Show InChI InChI=1S/C29H28ClNO6S/c1-17(2)16-31(20-9-11-21(12-10-20)37-22-13-18(3)27(30)19(4)14-22)38(35,36)26-15-25(29(33)34)28(32)24-8-6-5-7-23(24)26/h5-15,17,32H,16H2,1-4H3,(H,33,34)
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 80n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158322
PNG
(CHEMBL3780225 | US10858316, Compound 3bd)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc(Oc2cccc3ccccc23)cc1
Show InChI InChI=1S/C27H19NO6S/c29-26-22-10-4-3-9-21(22)25(16-23(26)27(30)31)35(32,33)28-18-12-14-19(15-13-18)34-24-11-5-7-17-6-1-2-8-20(17)24/h1-16,28-29H,(H,30,31)
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 82n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158324
PNG
(CHEMBL3780311 | US10858316, Compound 3be)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc(Oc2cccc(Br)c2)cc1
Show InChI InChI=1S/C23H16BrNO6S/c24-14-4-3-5-17(12-14)31-16-10-8-15(9-11-16)25-32(29,30)21-13-20(23(27)28)22(26)19-7-2-1-6-18(19)21/h1-13,25-26H,(H,27,28)
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 114n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158333
PNG
(CHEMBL3780473 | US10858316, Compound 3bi)
Show SMILES Cc1cc(Oc2ccc(NS(=O)(=O)c3cc(C(O)=O)c(O)c4ccccc34)cc2)cc(C)c1Cl
Show InChI InChI=1S/C25H20ClNO6S/c1-14-11-18(12-15(2)23(14)26)33-17-9-7-16(8-10-17)27-34(31,32)22-13-21(25(29)30)24(28)20-6-4-3-5-19(20)22/h3-13,27-28H,1-2H3,(H,29,30)
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 117n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158332
PNG
(CHEMBL3780719 | US10858316, Compound 3bh)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc(Oc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C23H16ClNO6S/c24-14-5-9-16(10-6-14)31-17-11-7-15(8-12-17)25-32(29,30)21-13-20(23(27)28)22(26)19-4-2-1-3-18(19)21/h1-13,25-26H,(H,27,28)
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 173n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158325
PNG
(CHEMBL3781894 | US10858316, Compound 3bf)
Show SMILES Cc1cc(C)cc(Oc2ccc(NS(=O)(=O)c3cc(C(O)=O)c(O)c4ccccc34)cc2)c1
Show InChI InChI=1S/C25H21NO6S/c1-15-11-16(2)13-19(12-15)32-18-9-7-17(8-10-18)26-33(30,31)23-14-22(25(28)29)24(27)21-6-4-3-5-20(21)23/h3-14,26-27H,1-2H3,(H,28,29)
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 284n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158186
PNG
(CHEMBL3781396 | US10858316, Compound 3bc)
Show SMILES Cc1ccc(Oc2ccc(NS(=O)(=O)c3cc(C(O)=O)c(O)c4ccccc34)cc2)cc1
Show InChI InChI=1S/C24H19NO6S/c1-15-6-10-17(11-7-15)31-18-12-8-16(9-13-18)25-32(29,30)22-14-21(24(27)28)23(26)20-5-3-2-4-19(20)22/h2-14,25-26H,1H3,(H,27,28)
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 335n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158168
PNG
(CHEMBL3780113 | US10858316, Compound 3o)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc(Br)cc1Br
Show InChI InChI=1S/C17H11Br2NO5S/c18-9-5-6-14(13(19)7-9)20-26(24,25)15-8-12(17(22)23)16(21)11-4-2-1-3-10(11)15/h1-8,20-21H,(H,22,23)
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 420n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158184
PNG
(CHEMBL3780576 | US10858316, Compound 3ba)
Show SMILES CC(C)CN(c1ccc(OC(C)C)cc1)S(=O)(=O)c1cc(C(O)=O)c(O)c2ccccc12
Show InChI InChI=1S/C24H27NO6S/c1-15(2)14-25(17-9-11-18(12-10-17)31-16(3)4)32(29,30)22-13-21(24(27)28)23(26)20-8-6-5-7-19(20)22/h5-13,15-16,26H,14H2,1-4H3,(H,27,28)
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 487n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158356
PNG
(CHEMBL3781019 | US10858316, Compound 3ca)
Show SMILES CC(C)CN(c1ccc(Br)cc1)S(=O)(=O)c1cc(C(O)=O)c(O)c2ccccc12
Show InChI InChI=1S/C21H20BrNO5S/c1-13(2)12-23(15-9-7-14(22)8-10-15)29(27,28)19-11-18(21(25)26)20(24)17-6-4-3-5-16(17)19/h3-11,13,24H,12H2,1-2H3,(H,25,26)
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 566n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158185
PNG
(CHEMBL3781946 | US10858316, Compound 3bb)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C23H17NO6S/c25-22-19-9-5-4-8-18(19)21(14-20(22)23(26)27)31(28,29)24-15-10-12-17(13-11-15)30-16-6-2-1-3-7-16/h1-14,24-25H,(H,26,27)
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 1.15E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158173
PNG
(CHEMBL3780617 | US10858316, Compound 3t)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C23H17NO5S/c25-22-19-9-5-4-8-18(19)21(14-20(22)23(26)27)30(28,29)24-17-12-10-16(11-13-17)15-6-2-1-3-7-15/h1-14,24-25H,(H,26,27)
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 1.54E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158172
PNG
(CHEMBL3780990 | US10858316, Compound 3s)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C23H17NO5S/c25-22-19-12-5-4-11-18(19)21(14-20(22)23(26)27)30(28,29)24-17-10-6-9-16(13-17)15-7-2-1-3-8-15/h1-14,24-25H,(H,26,27)
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 1.88E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158175
PNG
(CHEMBL3780290 | US10858316, Compound 3v)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C17H12ClNO5S/c18-10-5-7-11(8-6-10)19-25(23,24)15-9-14(17(21)22)16(20)13-4-2-1-3-12(13)15/h1-9,19-20H,(H,21,22)
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 1.91E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158176
PNG
(CHEMBL3781065 | US10858316, Compound 3w)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C18H12F3NO5S/c19-18(20,21)10-5-7-11(8-6-10)22-28(26,27)15-9-14(17(24)25)16(23)13-4-2-1-3-12(13)15/h1-9,22-23H,(H,24,25)
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 2.50E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158081
PNG
(CHEMBL3781059 | US10858316, Compound 3a)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C17H12BrNO5S/c18-10-5-7-11(8-6-10)19-25(23,24)15-9-14(17(21)22)16(20)13-4-2-1-3-12(13)15/h1-9,19-20H,(H,21,22)
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 2.76E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158096
PNG
(CHEMBL3780988)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)N1CCCCC1
Show InChI InChI=1S/C16H17NO5S/c18-15-12-7-3-2-6-11(12)14(10-13(15)16(19)20)23(21,22)17-8-4-1-5-9-17/h2-3,6-7,10,18H,1,4-5,8-9H2,(H,19,20)
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 2.95E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158099
PNG
(CHEMBL3781593)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H22N2O5S/c25-21-18-9-5-4-8-17(18)20(14-19(21)22(26)27)30(28,29)24-12-10-23(11-13-24)15-16-6-2-1-3-7-16/h1-9,14,25H,10-13,15H2,(H,26,27)
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 3.41E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158178
PNG
(CHEMBL3781692 | US10858316, Compound 3y)
Show SMILES CC(C)c1ccc(NS(=O)(=O)c2cc(C(O)=O)c(O)c3ccccc23)cc1
Show InChI InChI=1S/C20H19NO5S/c1-12(2)13-7-9-14(10-8-13)21-27(25,26)18-11-17(20(23)24)19(22)16-6-4-3-5-15(16)18/h3-12,21-22H,1-2H3,(H,23,24)
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 3.86E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158174
PNG
(CHEMBL3781823 | US10858316, Compound 3u)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccccc1C(F)(F)F
Show InChI InChI=1S/C18H12F3NO5S/c19-18(20,21)13-7-3-4-8-14(13)22-28(26,27)15-9-12(17(24)25)16(23)11-6-2-1-5-10(11)15/h1-9,22-23H,(H,24,25)
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 4.05E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158182
PNG
(CHEMBL3781264 | US10858316, Compound 3ac)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C17H12N2O7S/c20-16-13-4-2-1-3-12(13)15(9-14(16)17(21)22)27(25,26)18-10-5-7-11(8-6-10)19(23)24/h1-9,18,20H,(H,21,22)
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 4.49E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158098
PNG
(CHEMBL3780385)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C21H20N2O5S/c24-20-17-9-5-4-8-16(17)19(14-18(20)21(25)26)29(27,28)23-12-10-22(11-13-23)15-6-2-1-3-7-15/h1-9,14,24H,10-13H2,(H,25,26)
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 4.54E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158170
PNG
(CHEMBL3781502 | US10858316, Compound 3q)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C21H15NO5S/c23-20-17-8-4-3-7-16(17)19(12-18(20)21(24)25)28(26,27)22-15-10-9-13-5-1-2-6-14(13)11-15/h1-12,22-23H,(H,24,25)
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 4.58E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158090
PNG
(CHEMBL3781868 | US10858316, Compound 3e)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)NCc1cccc(Cl)c1
Show InChI InChI=1S/C18H14ClNO5S/c19-12-5-3-4-11(8-12)10-20-26(24,25)16-9-15(18(22)23)17(21)14-7-2-1-6-13(14)16/h1-9,20-21H,10H2,(H,22,23)
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 5.03E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158167
PNG
(CHEMBL3780899 | US10858316, Compound 3n)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1cccc(Br)c1
Show InChI InChI=1S/C17H12BrNO5S/c18-10-4-3-5-11(8-10)19-25(23,24)15-9-14(17(21)22)16(20)13-7-2-1-6-12(13)15/h1-9,19-20H,(H,21,22)
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 5.64E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158166
PNG
(CHEMBL3781478 | US10858316, Compound 3m)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccccc1Br
Show InChI InChI=1S/C17H12BrNO5S/c18-13-7-3-4-8-14(13)19-25(23,24)15-9-12(17(21)22)16(20)11-6-2-1-5-10(11)15/h1-9,19-20H,(H,21,22)
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 6.84E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158092
PNG
(CHEMBL3780058 | US10858316, Compound 3g)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)NCC1CCCCC1
Show InChI InChI=1S/C18H21NO5S/c20-17-14-9-5-4-8-13(14)16(10-15(17)18(21)22)25(23,24)19-11-12-6-2-1-3-7-12/h4-5,8-10,12,19-20H,1-3,6-7,11H2,(H,21,22)
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 7.31E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158171
PNG
(CHEMBL3780451 | US10858316, Compound 3r)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccccc1-c1ccccc1
Show InChI InChI=1S/C23H17NO5S/c25-22-18-12-5-4-11-17(18)21(14-19(22)23(26)27)30(28,29)24-20-13-7-6-10-16(20)15-8-2-1-3-9-15/h1-14,24-25H,(H,26,27)
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 8.50E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158169
PNG
(CHEMBL3780357 | US10858316, Compound 3p)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1cccc2ccccc12
Show InChI InChI=1S/C21H15NO5S/c23-20-16-10-4-3-9-15(16)19(12-17(20)21(24)25)28(26,27)22-18-11-5-7-13-6-1-2-8-14(13)18/h1-12,22-23H,(H,24,25)
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 1.12E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158179
PNG
(CHEMBL3780070 | US10858316, Compound 3z)
Show SMILES COc1ccc(NS(=O)(=O)c2cc(C(O)=O)c(O)c3ccccc23)cc1
Show InChI InChI=1S/C18H15NO6S/c1-25-12-8-6-11(7-9-12)19-26(23,24)16-10-15(18(21)22)17(20)14-5-3-2-4-13(14)16/h2-10,19-20H,1H3,(H,21,22)
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 1.19E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158091
PNG
(CHEMBL3780331 | US10858316, Compound 3f)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)NCc1ccc(Cl)cc1
Show InChI InChI=1S/C18H14ClNO5S/c19-12-7-5-11(6-8-12)10-20-26(24,25)16-9-15(18(22)23)17(21)14-4-2-1-3-13(14)16/h1-9,20-21H,10H2,(H,22,23)
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 2.10E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158181
PNG
(CHEMBL3780766 | US10858316, Compound 3ab)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccc(cc1)C#N
Show InChI InChI=1S/C18H12N2O5S/c19-10-11-5-7-12(8-6-11)20-26(24,25)16-9-15(18(22)23)17(21)14-4-2-1-3-13(14)16/h1-9,20-21H,(H,22,23)
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 2.22E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158359
PNG
(CHEMBL3779915 | US10858316, Compound 3cd)
Show SMILES COc1c(cc(c2ccccc12)S(=O)(=O)N(CC(C)C)c1ccc(Br)cc1)C(O)=O
Show InChI InChI=1S/C22H22BrNO5S/c1-14(2)13-24(16-10-8-15(23)9-11-16)30(27,28)20-12-19(22(25)26)21(29-3)18-7-5-4-6-17(18)20/h4-12,14H,13H2,1-3H3,(H,25,26)
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 2.34E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158093
PNG
(CHEMBL3780614 | US10858316, Compound 3h)
Show SMILES CN(C)S(=O)(=O)c1cc(C(O)=O)c(O)c2ccccc12
Show InChI InChI=1S/C13H13NO5S/c1-14(2)20(18,19)11-7-10(13(16)17)12(15)9-6-4-3-5-8(9)11/h3-7,15H,1-2H3,(H,16,17)
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 2.57E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158183
PNG
(CHEMBL3780382 | US10858316, Compound 3ad)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1cccc(c1)C#N
Show InChI InChI=1S/C18H12N2O5S/c19-10-11-4-3-5-12(8-11)20-26(24,25)16-9-15(18(22)23)17(21)14-7-2-1-6-13(14)16/h1-9,20-21H,(H,22,23)
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 2.69E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158177
PNG
(CHEMBL3780094 | US10858316, Compound 3x)
Show SMILES Cc1ccc(NS(=O)(=O)c2cc(C(O)=O)c(O)c3ccccc23)cc1
Show InChI InChI=1S/C18H15NO5S/c1-11-6-8-12(9-7-11)19-25(23,24)16-10-15(18(21)22)17(20)14-5-3-2-4-13(14)16/h2-10,19-20H,1H3,(H,21,22)
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 3.43E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158089
PNG
(CHEMBL3781306 | US10858316, Compound 3d)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)NCc1ccccc1Cl
Show InChI InChI=1S/C18H14ClNO5S/c19-15-8-4-1-5-11(15)10-20-26(24,25)16-9-14(18(22)23)17(21)13-7-3-2-6-12(13)16/h1-9,20-21H,10H2,(H,22,23)
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 5.03E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158180
PNG
(CHEMBL3780580 | US10858316, Compound 3aa)
Show SMILES CC(C)Oc1ccc(NS(=O)(=O)c2cc(C(O)=O)c(O)c3ccccc23)cc1
Show InChI InChI=1S/C20H19NO6S/c1-12(2)27-14-9-7-13(8-10-14)21-28(25,26)18-11-17(20(23)24)19(22)16-6-4-3-5-15(16)18/h3-12,21-22H,1-2H3,(H,23,24)
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 5.40E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158088
PNG
(CHEMBL3780355 | US10858316, Compound 3c)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)NCc1ccccc1
Show InChI InChI=1S/C18H15NO5S/c20-17-14-9-5-4-8-13(14)16(10-15(17)18(21)22)25(23,24)19-11-12-6-2-1-3-7-12/h1-10,19-20H,11H2,(H,21,22)
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 5.63E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158086
PNG
(CHEMBL1410420 | US10858316, Compound 3b)
Show SMILES NS(=O)(=O)c1cc(C(O)=O)c(O)c2ccccc12
Show InChI InChI=1S/C11H9NO5S/c12-18(16,17)9-5-8(11(14)15)10(13)7-4-2-1-3-6(7)9/h1-5,13H,(H,14,15)(H2,12,16,17)
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 9.90E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158165
PNG
(CHEMBL3780724 | US10858316, Compound 3l)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C17H13NO5S/c19-16-13-9-5-4-8-12(13)15(10-14(16)17(20)21)24(22,23)18-11-6-2-1-3-7-11/h1-10,18-19H,(H,20,21)
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 1.06E+5n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158357
PNG
(CHEMBL3780242 | US10858316, Compound 3cb)
Show SMILES COC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)N(CC(C)C)c1ccc(Br)cc1
Show InChI InChI=1S/C22H22BrNO5S/c1-14(2)13-24(16-10-8-15(23)9-11-16)30(27,28)20-12-19(22(26)29-3)21(25)18-7-5-4-6-17(18)20/h4-12,14,25H,13H2,1-3H3
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>5.00E+5n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM50158358
PNG
(CHEMBL3781985 | US10858316, Compound 3cc)
Show SMILES COC(=O)c1cc(c2ccccc2c1OC)S(=O)(=O)N(CC(C)C)c1ccc(Br)cc1
Show InChI InChI=1S/C23H24BrNO5S/c1-15(2)14-25(17-11-9-16(24)10-12-17)31(27,28)21-13-20(23(26)30-4)22(29-3)19-8-6-5-7-18(19)21/h5-13,15H,14H2,1-4H3
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>5.00E+5n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...

Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%