Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone-lysine N-methyltransferase SETD7 (Homo sapiens (Human)) | BDBM50017721 (1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RIKEN Curated by ChEMBL | Assay Description Inhibition of recombinant Set7/9 (unknown origin) expressed in Escherichia coli BL21 (DE3) using Ac-KRSK-MCA peptide/SAM as substrate preincubated fo... | J Med Chem 59: 3650-60 (2016) Article DOI: 10.1021/acs.jmedchem.5b01732 BindingDB Entry DOI: 10.7270/Q2X068Z4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Histone-lysine N-methyltransferase SETD7 (Homo sapiens (Human)) | BDBM50017721 (1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
RIKEN Curated by ChEMBL | Assay Description Inhibition of recombinant Set7/9 (unknown origin) expressed in Escherichia coli BL21 (DE3) using biotinylated histone H3-derived peptide/SAM as subst... | J Med Chem 59: 3650-60 (2016) Article DOI: 10.1021/acs.jmedchem.5b01732 BindingDB Entry DOI: 10.7270/Q2X068Z4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Histone-lysine N-methyltransferase SETD7 (Homo sapiens (Human)) | BDBM50173506 (CHEMBL3809236) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
RIKEN Curated by ChEMBL | Assay Description Inhibition of recombinant Set7/9 (unknown origin) expressed in Escherichia coli BL21 (DE3) using biotinylated histone H3-derived peptide/SAM as subst... | J Med Chem 59: 3650-60 (2016) Article DOI: 10.1021/acs.jmedchem.5b01732 BindingDB Entry DOI: 10.7270/Q2X068Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase SETD7 (Homo sapiens (Human)) | BDBM50173505 (CHEMBL3809273) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RIKEN Curated by ChEMBL | Assay Description Inhibition of recombinant Set7/9 (unknown origin) expressed in Escherichia coli BL21 (DE3) using biotinylated histone H3-derived peptide/SAM as subst... | J Med Chem 59: 3650-60 (2016) Article DOI: 10.1021/acs.jmedchem.5b01732 BindingDB Entry DOI: 10.7270/Q2X068Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase SETD7 (Homo sapiens (Human)) | BDBM50173504 (CHEMBL3809971) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
RIKEN Curated by ChEMBL | Assay Description Inhibition of recombinant Set7/9 (unknown origin) expressed in Escherichia coli BL21 (DE3) using biotinylated histone H3-derived peptide/SAM as subst... | J Med Chem 59: 3650-60 (2016) Article DOI: 10.1021/acs.jmedchem.5b01732 BindingDB Entry DOI: 10.7270/Q2X068Z4 | |||||||||||
More data for this Ligand-Target Pair |