Affinity Data by PubMed id=27106710

PubMed code 27106710

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Large neutral amino acids transporter small subunit 1 (Homo sapiens (Human))	BDBM50174344 (CHEMBL58129) Show SMILES N[C@@H](Cc1cccc(c1)-c1ccccc1)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Kearney Curated by ChEMBL					Assay Description Inhibition of human LAT1 expressed in HEK cells assessed as reduction in uptake of [3H]-gabapentin after 3 mins by scintillation counting based cis-i...				Bioorg Med Chem Lett 26: 2616-2621 (2016) Article DOI: 10.1016/j.bmcl.2016.04.023 BindingDB Entry DOI: 10.7270/Q2ZS2ZFD
University of Nebraska Kearney Curated by ChEMBL					More data for this Ligand-Target Pair
Large neutral amino acids transporter small subunit 1 (Homo sapiens (Human))	BDBM50174345 (CHEMBL3809112) Show SMILES N[C@@H](Cc1cccc(Cc2ccccc2)c1)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Kearney Curated by ChEMBL					Assay Description Inhibition of human LAT1 expressed in HEK cells assessed as reduction in uptake of [3H]-gabapentin after 3 mins by scintillation counting based cis-i...				Bioorg Med Chem Lett 26: 2616-2621 (2016) Article DOI: 10.1016/j.bmcl.2016.04.023 BindingDB Entry DOI: 10.7270/Q2ZS2ZFD
University of Nebraska Kearney Curated by ChEMBL					More data for this Ligand-Target Pair
Large neutral amino acids transporter small subunit 1 (Homo sapiens (Human))	BDBM50174343 (CHEMBL3809645) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Kearney Curated by ChEMBL					Assay Description Inhibition of human LAT1 expressed in HEK cells assessed as reduction in uptake of [3H]-gabapentin after 3 mins by scintillation counting based cis-i...				Bioorg Med Chem Lett 26: 2616-2621 (2016) Article DOI: 10.1016/j.bmcl.2016.04.023 BindingDB Entry DOI: 10.7270/Q2ZS2ZFD
University of Nebraska Kearney Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%