Affinity Data by PubMed id=27282741

PubMed code 27282741

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50067584 ((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189292 (CHEMBL3828157) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189293 (CHEMBL3827279) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189295 (CHEMBL3828384) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50059863 ((Z)-2-Methyl-3-tetradecyl-but-2-enedioic acid \| CH...) Show SMILES CCCCCCCCCCCCCC\C(C(O)=O)=C(/C)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189304 (CHEMBL3827991) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	602	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189297 (CHEMBL3828545) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	711	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189301 (CHEMBL3827237) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	726	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189302 (CHEMBL3827637) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	931	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189300 (CHEMBL3826996) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189303 (CHEMBL3828130) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189299 (CHEMBL3828274) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189294 (CHEMBL3827132) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189296 (CHEMBL3827509) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50189298 (CHEMBL3826985) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) Article DOI: 10.1016/j.bmcl.2016.05.074 BindingDB Entry DOI: 10.7270/Q2DR2XFP
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%