Affinity Data by PubMed id=27689388

PubMed code 27689388

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM205479 (PDD00017273 (4) \| US20230278998, Compound PDD00017...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	7.4	n/a
University of Manchester					Assay Description Briefly, PARG in vitro assays were conducted in a total volume of 15 μL in a standard 384-well format. A total of 5 μL of human full length...				ACS Chem Biol 11: 3179-3190 (2016) Article DOI: 10.1021/acschembio.6b00609 BindingDB Entry DOI: 10.7270/Q2BP01NJ
University of Manchester					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM205480 (PDD00017238 (5) \| US10508086, Example 90 \| US10995...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	7.4	n/a
University of Manchester					Assay Description Briefly, PARG in vitro assays were conducted in a total volume of 15 μL in a standard 384-well format. A total of 5 μL of human full length...				ACS Chem Biol 11: 3179-3190 (2016) Article DOI: 10.1021/acschembio.6b00609 BindingDB Entry DOI: 10.7270/Q2BP01NJ
University of Manchester					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM205482 (PDD00031705 (7)) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
University of Manchester					Assay Description Briefly, PARG in vitro assays were conducted in a total volume of 15 μL in a standard 384-well format. A total of 5 μL of human full length...				ACS Chem Biol 11: 3179-3190 (2016) Article DOI: 10.1021/acschembio.6b00609 BindingDB Entry DOI: 10.7270/Q2BP01NJ
University of Manchester					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM205478 (PDD00013907 (1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
University of Manchester					Assay Description Briefly, PARG in vitro assays were conducted in a total volume of 15 μL in a standard 384-well format. A total of 5 μL of human full length...				ACS Chem Biol 11: 3179-3190 (2016) Article DOI: 10.1021/acschembio.6b00609 BindingDB Entry DOI: 10.7270/Q2BP01NJ
University of Manchester					More data for this Ligand-Target Pair				3D Structure (crystal)
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM205481 (PDD00031704 (6)) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
University of Manchester					Assay Description Briefly, PARG in vitro assays were conducted in a total volume of 15 μL in a standard 384-well format. A total of 5 μL of human full length...				ACS Chem Biol 11: 3179-3190 (2016) Article DOI: 10.1021/acschembio.6b00609 BindingDB Entry DOI: 10.7270/Q2BP01NJ
University of Manchester					More data for this Ligand-Target Pair

* indicates data uncertainty>20%