Affinity Data by PubMed id=27943581

PubMed code 27943581

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50328678 (6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexa...) Show SMILES ONC(=O)CCCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney					Assay Description A FLUOR DE LYS fluorometric activity assay kit (HDAC source: HeLa cell nuclear extract) and a FLUOR DE LYS HDAC1 fluorometric drug discovery assay ki...				Chembiochem 18: 368-373 (2017) Article DOI: 10.1002/cbic.201600636 BindingDB Entry DOI: 10.7270/Q2RV0MH7
The University of Sydney					More data for this Ligand-Target Pair
Lipoxygenase (Solanum tuberosum (potato))	BDBM22334 (BW A4C \| BW4C \| BWA4C \| BWA4C, 10 \| CHEMBL314360 \|...) Show SMILES CC(=O)N(O)C\C=C\c1cccc(Oc2ccccc2)c1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney					Assay Description A colorimetric 5-LO assay kit (Lipoxygenase Inhibitor Screening Assay Kit) and potato 5-LO isolate were purchased from Cayman Chemicals (Ann Arbor, M...				Chembiochem 18: 368-373 (2017) Article DOI: 10.1002/cbic.201600636 BindingDB Entry DOI: 10.7270/Q2RV0MH7
The University of Sydney					More data for this Ligand-Target Pair
Lipoxygenase (Solanum tuberosum (potato))	BDBM218835 (BIQD-substituted compound, S2) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney					Assay Description A colorimetric 5-LO assay kit (Lipoxygenase Inhibitor Screening Assay Kit) and potato 5-LO isolate were purchased from Cayman Chemicals (Ann Arbor, M...				Chembiochem 18: 368-373 (2017) Article DOI: 10.1002/cbic.201600636 BindingDB Entry DOI: 10.7270/Q2RV0MH7
The University of Sydney					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM218835 (BIQD-substituted compound, S2) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.72E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney					Assay Description A FLUOR DE LYS fluorometric activity assay kit (HDAC source: HeLa cell nuclear extract) and a FLUOR DE LYS HDAC1 fluorometric drug discovery assay ki...				Chembiochem 18: 368-373 (2017) Article DOI: 10.1002/cbic.201600636 BindingDB Entry DOI: 10.7270/Q2RV0MH7
The University of Sydney					More data for this Ligand-Target Pair
Lipoxygenase (Solanum tuberosum (potato))	BDBM50328678 (6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexa...) Show SMILES ONC(=O)CCCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney					Assay Description A colorimetric 5-LO assay kit (Lipoxygenase Inhibitor Screening Assay Kit) and potato 5-LO isolate were purchased from Cayman Chemicals (Ann Arbor, M...				Chembiochem 18: 368-373 (2017) Article DOI: 10.1002/cbic.201600636 BindingDB Entry DOI: 10.7270/Q2RV0MH7
The University of Sydney					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM218834 (BIQD-substituted compound, S1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.58E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney					Assay Description A FLUOR DE LYS fluorometric activity assay kit (HDAC source: HeLa cell nuclear extract) and a FLUOR DE LYS HDAC1 fluorometric drug discovery assay ki...				Chembiochem 18: 368-373 (2017) Article DOI: 10.1002/cbic.201600636 BindingDB Entry DOI: 10.7270/Q2RV0MH7
The University of Sydney					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM218836 (BIQD-substituted compound, S5) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney					Assay Description A FLUOR DE LYS fluorometric activity assay kit (HDAC source: HeLa cell nuclear extract) and a FLUOR DE LYS HDAC1 fluorometric drug discovery assay ki...				Chembiochem 18: 368-373 (2017) Article DOI: 10.1002/cbic.201600636 BindingDB Entry DOI: 10.7270/Q2RV0MH7
The University of Sydney					More data for this Ligand-Target Pair
Lipoxygenase (Solanum tuberosum (potato))	BDBM218836 (BIQD-substituted compound, S5) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.34E+6	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney					Assay Description A colorimetric 5-LO assay kit (Lipoxygenase Inhibitor Screening Assay Kit) and potato 5-LO isolate were purchased from Cayman Chemicals (Ann Arbor, M...				Chembiochem 18: 368-373 (2017) Article DOI: 10.1002/cbic.201600636 BindingDB Entry DOI: 10.7270/Q2RV0MH7
The University of Sydney					More data for this Ligand-Target Pair

* indicates data uncertainty>20%