Affinity Data by PubMed id=28089350

PubMed code 28089350

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM76305 (5-chloranylquinolin-8-ol \| 5-chloro-8-quinolinol \|...) Show SMILES Oc1ccc(Cl)c2cccnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using ...				Bioorg Med Chem 25: 813-824 (2017) Article DOI: 10.1016/j.bmc.2016.11.013 BindingDB Entry DOI: 10.7270/Q2125VV2
Northern Illinois University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM32203 (8-quinolinol \| CHEMBL310555 \| US10005735, Table 1....) Show SMILES Oc1cccc2cccnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using ...				Bioorg Med Chem 25: 813-824 (2017) Article DOI: 10.1016/j.bmc.2016.11.013 BindingDB Entry DOI: 10.7270/Q2125VV2
Northern Illinois University Curated by ChEMBL					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM50065785 (2-Methyl-quinolin-8-ol \| CHEMBL316892) Show SMILES Cc1ccc2cccc(O)c2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using ...				Bioorg Med Chem 25: 813-824 (2017) Article DOI: 10.1016/j.bmc.2016.11.013 BindingDB Entry DOI: 10.7270/Q2125VV2
Northern Illinois University Curated by ChEMBL					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM32203 (8-quinolinol \| CHEMBL310555 \| US10005735, Table 1....) Show SMILES Oc1cccc2cccnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged methionine aminopeptidase 1 expressed in Escherichia coli BL21(DE3) using methionylprolyl-p-ni...				Bioorg Med Chem 25: 813-824 (2017) Article DOI: 10.1016/j.bmc.2016.11.013 BindingDB Entry DOI: 10.7270/Q2125VV2
Northern Illinois University Curated by ChEMBL					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM76305 (5-chloranylquinolin-8-ol \| 5-chloro-8-quinolinol \|...) Show SMILES Oc1ccc(Cl)c2cccnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged methionine aminopeptidase 1 expressed in Escherichia coli BL21(DE3) using methionylprolyl-p-ni...				Bioorg Med Chem 25: 813-824 (2017) Article DOI: 10.1016/j.bmc.2016.11.013 BindingDB Entry DOI: 10.7270/Q2125VV2
Northern Illinois University Curated by ChEMBL					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM50211290 (CHEMBL2407096) Show SMILES CC(C)(C)c1ccc(CSc2nnc(N)[nH]2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using ...				Bioorg Med Chem 25: 813-824 (2017) Article DOI: 10.1016/j.bmc.2016.11.013 BindingDB Entry DOI: 10.7270/Q2125VV2
Northern Illinois University Curated by ChEMBL					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50065785 (2-Methyl-quinolin-8-ol \| CHEMBL316892) Show SMILES Cc1ccc2cccc(O)c2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged methionine aminopeptidase 1 expressed in Escherichia coli BL21(DE3) using methionylprolyl-p-ni...				Bioorg Med Chem 25: 813-824 (2017) Article DOI: 10.1016/j.bmc.2016.11.013 BindingDB Entry DOI: 10.7270/Q2125VV2
Northern Illinois University Curated by ChEMBL					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50211290 (CHEMBL2407096) Show SMILES CC(C)(C)c1ccc(CSc2nnc(N)[nH]2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged methionine aminopeptidase 1 expressed in Escherichia coli BL21(DE3) using methionylprolyl-p-ni...				Bioorg Med Chem 25: 813-824 (2017) Article DOI: 10.1016/j.bmc.2016.11.013 BindingDB Entry DOI: 10.7270/Q2125VV2
Northern Illinois University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%