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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222236 (4-((7-Chloro-3-(hydroxyimino)-2-oxoindolin-1-yl)me...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222235 (N-Hydroxy-4-((3-(hydroxyimino)-5-methoxy-2-oxoindo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222233 (4-((5-Bromo-3-(hydroxyimino)-2-oxoindolin-1-yl)met...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222234 (N-Hydroxy-4-((3-(hydroxyimino)-5-methyl-2-oxoindol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222237 (N-hydroxy-4-((3-(hydroxyimino)-5-nitro-2-oxoindoli...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222227 (N-Hydroxy-4-((4-((3-(hydroxyimino)-5-methyl-2-oxoi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222226 (4-((4-((5-Bromo-3-(hydroxyimino)-2-oxoindolin-1-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222231 (4-((5-Fluoro-3-(hydroxyimino)-2-oxoindolin-1-yl)me...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 940 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222232 (4-((5-Chloro-3-(hydroxyimino)-2-oxoindolin-1-yl)me...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222223 (N-Hydroxy-4-((4-((3-(hydroxyimino)-2-oxoindolin-1-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222225 (4-((4-((5-Chloro-3-(hydroxyimino)-2-oxoindolin-1-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222224 (4-((4-((5-Fluoro-3-(hydroxyimino)-2-oxoindolin-1-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222228 (N-Hydroxy-4-((4-((3-(hydroxyimino)-5-methoxy-2-oxo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222229 (4-((4-((7-Chloro-3-(hydroxyimino)-2-oxoindolin-1-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM222230 (N-Hydroxy-4-((3-(hydroxyimino)-2-oxoindolin-1-yl)m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanoi University of Pharmacy | Assay Description The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,... | Bioorg Chem 71: 160-169 (2017) Article DOI: 10.1016/j.bioorg.2017.02.002 BindingDB Entry DOI: 10.7270/Q2TH8KJG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
