Affinity Data by PubMed id=28404526

PubMed code 28404526

Found 23 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cholinesterase (Equus caballus (Horse))	BDBM50241979 (CHEMBL4066365) Show SMILES CCO[P@](=O)(SCC)c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of equine BChE assessed as equilibrium constant using butyrylthiocholine iodide as substrate after 30 mins				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50241979 (CHEMBL4066365) Show SMILES CCO[P@](=O)(SCC)c1ccccc1 \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE assessed as equilibrium constant using acetylthiocholine as substrate after 30 mins				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50240416 (CHEMBL23838 \| O,O-diethyl O-p-nitrophenyl phosphat...) Show SMILES CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's method				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50240416 (CHEMBL23838 \| O,O-diethyl O-p-nitrophenyl phosphat...) Show SMILES CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE using p-nitrophenyl acetate as substrate measured for 30 secs by spectrophotometric analysis				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50241989 (CHEMBL2179375) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 30 min followed by substrate addition measured ever...				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50241979 (CHEMBL4066365) Show SMILES CCO[P@](=O)(SCC)c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of horse BChE using butyrylthiocholine iodide as substrate measured for 30 secs by Ellman's method				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50241979 (CHEMBL4066365) Show SMILES CCO[P@](=O)(SCC)c1ccccc1 \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE using acetylthiocholine iodide as substrate measured for 30 secs by Ellman's method				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50241988 (CHEMBL592433) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 30 min followed by substrate addition measured ever...				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50241981 (CHEMBL4072457) Show SMILES CSP(C)(=O)OC1CCCCC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometric analysis				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50241981 (CHEMBL4072457) Show SMILES CSP(C)(=O)OC1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's method				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50241979 (CHEMBL4066365) Show SMILES CCO[P@](=O)(SCC)c1ccccc1 \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of Electric eel AChE using acetylthiocholine iodide as substrate measured for 30 secs by Ellman's method				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50241978 (CHEMBL4093928) Show SMILES CCO[P@@](=O)(SCC)c1ccccc1 \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE using acetylthiocholine iodide as substrate measured for 30 secs by Ellman's method				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50241978 (CHEMBL4093928) Show SMILES CCO[P@@](=O)(SCC)c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of horse BChE using butyrylthiocholine iodide as substrate measured for 30 secs by Ellman's method				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50241980 (CHEMBL4097266) Show SMILES CSP(C)(=O)OC(C)C(C)(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's method				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50241978 (CHEMBL4093928) Show SMILES CCO[P@@](=O)(SCC)c1ccccc1 \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.65E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of Electric eel AChE using acetylthiocholine iodide as substrate measured for 30 secs by Ellman's method				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50241980 (CHEMBL4097266) Show SMILES CSP(C)(=O)OC(C)C(C)(C)C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometric analysis				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50241991 (CHEMBL4085438) Show SMILES COP(C)(=O)SCCN(C(C)C)C(C)C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Binding affinity to Electric eel AChE				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50241982 (CHEMBL4093201) Show SMILES CSP(C)(=O)OC(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.30E+6	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Binding affinity to human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's method				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50241987 (CHEMBL446997) Show SMILES CCOP(=O)(C#N)N(C)C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.45E+4	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Binding affinity to human AChE				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50027343 (CHEBI:75701 \| ISOPROPYL METHYLPHOSPHONOFLUORIDATE) Show SMILES CC(C)OP(C)(F)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Binding affinity to Electric eel AChE				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50241982 (CHEMBL4093201) Show SMILES CSP(C)(=O)OC(C)C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.50E+6	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Binding affinity to human AChE using acetylthiocholine as substrate by spectrophotometric analysis				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50240416 (CHEMBL23838 \| O,O-diethyl O-p-nitrophenyl phosphat...) Show SMILES CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Binding affinity to Electric eel AChE using acetylthiocholine as substrate measured for 30 secs by Ellman's method				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50292572 (3,3-dimethylbutan-2-yl methylphosphonofluoridate \|...) Show SMILES CC(OP(C)(F)=O)C(C)(C)C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a
University of Missouri St. Louis Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor from rat brain membranes using [3H]cyclohexyladenosine as radioligand.				Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09
University of Missouri St. Louis Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%