BindingDB logo
myBDB logout

PubMed code 28411455

Compile data set for download or QSAR
Found 45 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242005
PNG
(CHEMBL4104884)
Show SMILES CC(c1c(F)cc2ncc(cc2c1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1ccc(C(N)=O)c(F)c1
Show InChI InChI=1S/C26H18F3N9O/c1-12(22-19(28)7-20-17(23(22)29)5-14(8-31-20)15-9-33-37(2)11-15)38-26-25(35-36-38)32-10-21(34-26)13-3-4-16(24(30)39)18(27)6-13/h3-12H,1-2H3,(H2,30,39)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.300n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242000
PNG
(CHEMBL4061378)
Show SMILES CC(c1ccc2ncc(cc2c1)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1ccncc1
Show InChI InChI=1S/C24H19N9/c1-15(33-24-23(30-31-33)27-13-22(29-24)16-5-7-25-8-6-16)17-3-4-21-18(9-17)10-19(11-26-21)20-12-28-32(2)14-20/h3-15H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.300n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242011
PNG
(CHEMBL4070258)
Show SMILES CC(c1c(F)cc2ncc(cc2c1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H20F2N10O/c1-13(36-24-23(32-33-36)28-10-20(31-24)16-9-30-35(12-16)3-4-37)21-18(25)6-19-17(22(21)26)5-14(7-27-19)15-8-29-34(2)11-15/h5-13,37H,3-4H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 0.400n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242021
PNG
(CHEMBL4097173)
Show SMILES CC(c1c(F)cc2ncc(cc2c1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(C)c1
Show InChI InChI=1S/C23H18F2N10/c1-12(35-23-22(31-32-35)27-9-19(30-23)15-8-29-34(3)11-15)20-17(24)5-18-16(21(20)25)4-13(6-26-18)14-7-28-33(2)10-14/h4-12H,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 0.400n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50146167
PNG
(Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...)
Show SMILES CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1
Show InChI InChI=1S/C23H17FN6O/c1-25-22(31)18-6-5-16(11-19(18)24)21-13-28-23-27-12-17(30(23)29-21)10-14-4-7-20-15(9-14)3-2-8-26-20/h2-9,11-13H,10H2,1H3,(H,25,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.400n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.480n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.480n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50241998
PNG
(CHEMBL4064183)
Show SMILES CC(c1ccc2ncc(cc2c1)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H22N10O/c1-15(16-3-4-21-17(7-16)8-18(9-25-21)19-10-27-32(2)13-19)34-24-23(30-31-34)26-12-22(29-24)20-11-28-33(14-20)5-6-35/h3-4,7-15,35H,5-6H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.5n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242018
PNG
(CHEMBL4073110)
Show SMILES CC(c1ccc2ncc(cc2c1)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(C)c1
Show InChI InChI=1S/C23H20N10/c1-14(33-23-22(29-30-33)25-11-21(28-23)19-10-27-32(3)13-19)15-4-5-20-16(6-15)7-17(8-24-20)18-9-26-31(2)12-18/h4-14H,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.5n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242007
PNG
(CHEMBL4076438)
Show SMILES CC(c1c(F)cc2ncc(cc2c1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1ccncc1
Show InChI InChI=1S/C24H17F2N9/c1-13(35-24-23(32-33-35)29-11-20(31-24)14-3-5-27-6-4-14)21-18(25)8-19-17(22(21)26)7-15(9-28-19)16-10-30-34(2)12-16/h3-13H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 0.5n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242020
PNG
(CHEMBL4091023)
Show SMILES CNC(=O)c1ccc(cc1F)-c1cnc2nnn(C(C)c3ccc4ncc(cc4c3)-c3cnn(C)c3)c2n1
Show InChI InChI=1S/C27H22FN9O/c1-15(16-5-7-23-18(8-16)9-19(11-30-23)20-12-32-36(3)14-20)37-26-25(34-35-37)31-13-24(33-26)17-4-6-21(22(28)10-17)27(38)29-2/h4-15H,1-3H3,(H,29,38)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.5n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242002
PNG
(CHEMBL4060354)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1ccc(C(N)=O)c(F)c1
Show InChI InChI=1S/C26H19F2N9O/c1-13(19-6-15-5-16(17-10-32-36(2)12-17)9-30-22(15)8-21(19)28)37-26-25(34-35-37)31-11-23(33-26)14-3-4-18(24(29)38)20(27)7-14/h3-13H,1-2H3,(H2,29,38)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.600n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.680n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242004
PNG
(CHEMBL4068290)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1ccncc1
Show InChI InChI=1S/C24H18FN9/c1-14(34-24-23(31-32-34)28-12-22(30-24)15-3-5-26-6-4-15)19-8-16-7-17(18-11-29-33(2)13-18)10-27-21(16)9-20(19)25/h3-14H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.700n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242001
PNG
(CHEMBL4083235)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(C)c1
Show InChI InChI=1S/C23H19FN10/c1-13(34-23-22(30-31-34)26-10-21(29-23)17-9-28-33(3)12-17)18-5-14-4-15(16-8-27-32(2)11-16)7-25-20(14)6-19(18)24/h4-13H,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.700n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50241999
PNG
(CHEMBL4070051)
Show SMILES CC(c1ccc2ncc(cc2c1)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1ccc(C(N)=O)c(F)c1
Show InChI InChI=1S/C26H20FN9O/c1-14(15-4-6-22-17(7-15)8-18(10-29-22)19-11-31-35(2)13-19)36-26-25(33-34-36)30-12-23(32-26)16-3-5-20(24(28)37)21(27)9-16/h3-14H,1-2H3,(H2,28,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.700n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242006
PNG
(CHEMBL4075149)
Show SMILES CNC(=O)c1ccc(cc1F)-c1cnc2nnn(C(C)c3c(F)cc4ncc(cc4c3F)-c3cnn(C)c3)c2n1
Show InChI InChI=1S/C27H20F3N9O/c1-13(23-20(29)8-21-18(24(23)30)6-15(9-32-21)16-10-34-38(3)12-16)39-26-25(36-37-39)33-11-22(35-26)14-4-5-17(19(28)7-14)27(40)31-2/h4-13H,1-3H3,(H,31,40)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.900n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242003
PNG
(CHEMBL4092293)
Show SMILES CNC(=O)c1ccc(cc1F)-c1cnc2nnn(C(C)c3cc4cc(cnc4cc3F)-c3cnn(C)c3)c2n1
Show InChI InChI=1S/C27H21F2N9O/c1-14(20-7-16-6-17(18-11-33-37(3)13-18)10-31-23(16)9-22(20)29)38-26-25(35-36-38)32-12-24(34-26)15-4-5-19(21(28)8-15)27(39)30-2/h4-14H,1-3H3,(H,30,39)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50241996
PNG
(CHEMBL4093803)
Show SMILES CC(c1ccc2ncc(cc2c1)-c1ccc(F)cc1)n1nnc2ncc(nc12)-c1cnn(C)c1
Show InChI InChI=1S/C25H19FN8/c1-15(34-25-24(31-32-34)28-13-23(30-25)20-12-29-33(2)14-20)17-5-8-22-18(9-17)10-19(11-27-22)16-3-6-21(26)7-4-16/h3-15H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.30n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242012
PNG
(CHEMBL4094716)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1ccc(F)cc1)n1nnc2ncc(nc12)-c1cnn(C)c1
Show InChI InChI=1S/C25H18F2N8/c1-14(35-25-24(32-33-35)29-12-23(31-25)18-11-30-34(2)13-18)20-8-16-7-17(10-28-22(16)9-21(20)27)15-3-5-19(26)6-4-15/h3-14H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.5n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242008
PNG
(CHEMBL4078192)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1ccc(F)cc1)n1nnc2ncc(nc12)-c1ccncc1
Show InChI InChI=1S/C26H17F2N7/c1-15(35-26-25(33-34-35)31-14-24(32-26)17-6-8-29-9-7-17)21-11-18-10-19(13-30-23(18)12-22(21)28)16-2-4-20(27)5-3-16/h2-15H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.70n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242019
PNG
(CHEMBL4072776)
Show SMILES CC(c1ccc2ncc(cc2c1)-c1ccc(F)cc1)n1nnc2ncc(nc12)-c1ccncc1
Show InChI InChI=1S/C26H18FN7/c1-16(34-26-25(32-33-34)30-15-24(31-26)18-8-10-28-11-9-18)19-4-7-23-20(12-19)13-21(14-29-23)17-2-5-22(27)6-3-17/h2-16H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50241997
PNG
(CHEMBL4099662)
Show SMILES CNC(=O)c1ccc(cc1F)-c1cnc2nnn(C(C)c3ccc4ncc(cc4c3)-c3ccc(F)cc3)c2n1
Show InChI InChI=1S/C29H21F2N7O/c1-16(18-6-10-25-20(11-18)12-21(14-33-25)17-3-7-22(30)8-4-17)38-28-27(36-37-38)34-15-26(35-28)19-5-9-23(24(31)13-19)29(39)32-2/h3-16H,1-2H3,(H,32,39)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.5n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242009
PNG
(CHEMBL4102466)
Show SMILES CC(c1c(F)cc2ncc(cc2c1F)-c1ccc(F)cc1)n1nnc2ncc(nc12)-c1cnn(C)c1
Show InChI InChI=1S/C25H17F3N8/c1-13(36-25-24(33-34-36)30-11-21(32-25)16-10-31-35(2)12-16)22-19(27)8-20-18(23(22)28)7-15(9-29-20)14-3-5-17(26)6-4-14/h3-13H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 3.80n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50242013
PNG
(CHEMBL4065641)
Show SMILES CC(c1c(F)cc2ncc(cc2c1F)-c1ccc(F)cc1)n1nnc2ncc(nc12)-c1ccncc1
Show InChI InChI=1S/C26H16F3N7/c1-14(36-26-25(34-35-36)32-13-22(33-26)16-6-8-30-9-7-16)23-20(28)11-21-19(24(23)29)10-17(12-31-21)15-2-4-18(27)5-3-15/h2-14H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 4.30n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50241994
PNG
(CHEMBL4059611)
Show SMILES CNC(=O)c1ccc(cc1F)-c1cnc2nnn(C(C)c3ccc4nc(ccc4c3)-c3cnn(C)c3)c2n1
Show InChI InChI=1S/C27H22FN9O/c1-15(16-5-8-22-17(10-16)6-9-23(32-22)19-12-31-36(3)14-19)37-26-25(34-35-37)30-13-24(33-26)18-4-7-20(21(28)11-18)27(38)29-2/h4-15H,1-3H3,(H,29,38)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 67n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50241993
PNG
(CHEMBL4089433)
Show SMILES CC(c1ccc2nc(ccc2c1)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(C)c1
Show InChI InChI=1S/C23H20N10/c1-14(33-23-22(29-30-33)24-11-21(28-23)18-10-26-32(3)13-18)15-4-6-19-16(8-15)5-7-20(27-19)17-9-25-31(2)12-17/h4-14H,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50241995
PNG
(CHEMBL4081567)
Show SMILES CC(c1ccc2nc(ccc2c1)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1ccc(N)cc1
Show InChI InChI=1S/C25H21N9/c1-15(17-5-9-21-18(11-17)6-10-22(29-21)19-12-28-33(2)14-19)34-25-24(31-32-34)27-13-23(30-25)16-3-7-20(26)8-4-16/h3-15H,26H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using TK substrate-biotin peptide as substrate preincubated for 5 to 10 mins followed by ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 731n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor UFO


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.08E+3n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Axl (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor alpha


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.36E+3n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition mea...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.40E+3n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-Kit (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.71E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of c-Src (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.84E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measure...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Ephrin type-A receptor 2


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of EPHA2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of FLT1 (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured ...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of RET (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of ABL (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of IGF1R (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-4


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of ERBB4 (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
ALK tyrosine kinase receptor


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of ALK (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured a...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of PDGFRbeta (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition meas...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Ephrin type-B receptor 2


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of EPHB2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50241992
PNG
(CHEMBL4074262)
Show SMILES CC(c1cc2cc(cnc2cc1F)-c1cnn(C)c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1
Show InChI InChI=1S/C24H21FN10O/c1-14(19-6-15-5-16(17-9-28-33(2)12-17)8-26-21(15)7-20(19)25)35-24-23(31-32-35)27-11-22(30-24)18-10-29-34(13-18)3-4-36/h5-14,36H,3-4H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of EGFR (unknown origin) using FAM-labeled peptide as substrate preincubated for 5 to 10 mins followed by substrate/ATP addition measured ...

Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%