Affinity Data by PubMed id=28442260

PubMed code 28442260

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Interleukin-6 (Homo sapiens (Human))	BDBM50252381 (CHEMBL4080826) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea. Curated by ChEMBL					Assay Description Inhibition of IL-6 signaling pathway in human HepG2 cells transfected with p-STAT3-Luc assessed as reduction in IL-6 induced STAT3 phosphorylation pr...				Bioorg Med Chem 25: 3127-3134 (2017) Article DOI: 10.1016/j.bmc.2017.03.072 BindingDB Entry DOI: 10.7270/Q2KW5JF6
					More data for this Ligand-Target Pair
Interleukin-6 (Homo sapiens (Human))	BDBM50252380 (CHEMBL4068283) Show SMILES CCc1ccc(Nc2nc3cc(N)ccc3o2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea. Curated by ChEMBL					Assay Description Inhibition of IL-6 signaling pathway in human HepG2 cells transfected with p-STAT3-Luc assessed as reduction in IL-6 induced STAT3 phosphorylation pr...				Bioorg Med Chem 25: 3127-3134 (2017) Article DOI: 10.1016/j.bmc.2017.03.072 BindingDB Entry DOI: 10.7270/Q2KW5JF6
					More data for this Ligand-Target Pair
Interleukin-6 (Homo sapiens (Human))	BDBM50252382 (CHEMBL4103291) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea. Curated by ChEMBL					Assay Description Inhibition of IL-6 signaling pathway in human HepG2 cells transfected with p-STAT3-Luc assessed as reduction in IL-6 induced STAT3 phosphorylation pr...				Bioorg Med Chem 25: 3127-3134 (2017) Article DOI: 10.1016/j.bmc.2017.03.072 BindingDB Entry DOI: 10.7270/Q2KW5JF6
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%