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PubMed code 28888661

Compile data set for download or QSAR
Found 23 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261615
PNG
(CHEMBL4076662)
Show SMILES COc1cc2CC3COC(=O)N3Cc2cc1OC1CCCC1
Show InChI InChI=1S/C17H21NO4/c1-20-15-7-11-6-13-10-21-17(19)18(13)9-12(11)8-16(15)22-14-4-2-3-5-14/h7-8,13-14H,2-6,9-10H2,1H3
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n/an/a 600n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM14361
PNG
((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1
Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)
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n/an/a 1.22E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261619
PNG
(CHEMBL4075410)
Show SMILES COc1cc2CC3COC(=O)N3Cc2cc1OCC1CC1
Show InChI InChI=1S/C16H19NO4/c1-19-14-5-11-4-13-9-21-16(18)17(13)7-12(11)6-15(14)20-8-10-2-3-10/h5-6,10,13H,2-4,7-9H2,1H3
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n/an/a 1.30E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261618
PNG
(CHEMBL4061114)
Show SMILES COc1cc2CC3COC(=O)N3C(C)c2cc1OC1CCCC1
Show InChI InChI=1S/C18H23NO4/c1-11-15-9-17(23-14-5-3-4-6-14)16(21-2)8-12(15)7-13-10-22-18(20)19(11)13/h8-9,11,13-14H,3-7,10H2,1-2H3
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n/an/a 1.35E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM14361
PNG
((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1
Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)
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n/an/a 1.43E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4D isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261613
PNG
(CHEMBL4063909)
Show SMILES COc1cc2CC3COC(=O)N3C(c3ccccc3)c2cc1OC1CCCC1
Show InChI InChI=1S/C23H25NO4/c1-26-20-12-16-11-17-14-27-23(25)24(17)22(15-7-3-2-4-8-15)19(16)13-21(20)28-18-9-5-6-10-18/h2-4,7-8,12-13,17-18,22H,5-6,9-11,14H2,1H3
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n/an/a 1.95E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261612
PNG
(CHEMBL4099426)
Show SMILES COc1cc2CC3COC(=O)N3C(C3CCCCC3)c2cc1OC1CCCC1
Show InChI InChI=1S/C23H31NO4/c1-26-20-12-16-11-17-14-27-23(25)24(17)22(15-7-3-2-4-8-15)19(16)13-21(20)28-18-9-5-6-10-18/h12-13,15,17-18,22H,2-11,14H2,1H3
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n/an/a 2.06E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261617
PNG
(CHEMBL4072507)
Show SMILES CCCCCCC1N2C(COC2=O)Cc2cc(OC)c(OC3CCCC3)cc12
Show InChI InChI=1S/C23H33NO4/c1-3-4-5-6-11-20-19-14-22(28-18-9-7-8-10-18)21(26-2)13-16(19)12-17-15-27-23(25)24(17)20/h13-14,17-18,20H,3-12,15H2,1-2H3
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n/an/a 2.10E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261614
PNG
(CHEMBL4082992)
Show SMILES COc1cc2CC3COC(=O)N3Cc2cc1OC1CCCCC1
Show InChI InChI=1S/C18H23NO4/c1-21-16-8-12-7-14-11-22-18(20)19(14)10-13(12)9-17(16)23-15-5-3-2-4-6-15/h8-9,14-15H,2-7,10-11H2,1H3
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n/an/a 2.62E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261616
PNG
(CHEMBL4077155)
Show SMILES CCCCCOc1cc2CN3C(COC3=O)Cc2cc1OC
Show InChI InChI=1S/C17H23NO4/c1-3-4-5-6-21-16-9-13-10-18-14(11-22-17(18)19)7-12(13)8-15(16)20-2/h8-9,14H,3-7,10-11H2,1-2H3
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n/an/a 4.10E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50261615
PNG
(CHEMBL4076662)
Show SMILES COc1cc2CC3COC(=O)N3Cc2cc1OC1CCCC1
Show InChI InChI=1S/C17H21NO4/c1-20-15-7-11-6-13-10-21-17(19)18(13)9-12(11)8-16(15)22-14-4-2-3-5-14/h7-8,13-14H,2-6,9-10H2,1H3
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n/an/a 5.13E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4D isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261620
PNG
(CHEMBL4061350)
Show SMILES CCCCCCOc1cc2CN3C(COC3=O)Cc2cc1OC
Show InChI InChI=1S/C18H25NO4/c1-3-4-5-6-7-22-17-10-14-11-19-15(12-23-18(19)20)8-13(14)9-16(17)21-2/h9-10,15H,3-8,11-12H2,1-2H3
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n/an/a 6.05E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50261619
PNG
(CHEMBL4075410)
Show SMILES COc1cc2CC3COC(=O)N3Cc2cc1OCC1CC1
Show InChI InChI=1S/C16H19NO4/c1-19-14-5-11-4-13-9-21-16(18)17(13)7-12(11)6-15(14)20-8-10-2-3-10/h5-6,10,13H,2-4,7-9H2,1H3
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n/an/a 7.15E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4D isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261623
PNG
(CHEMBL4095038)
Show SMILES COc1cc2CC3COC(=O)N3Cc2cc1OCc1ccccc1
Show InChI InChI=1S/C19H19NO4/c1-22-17-8-14-7-16-12-24-19(21)20(16)10-15(14)9-18(17)23-11-13-5-3-2-4-6-13/h2-6,8-9,16H,7,10-12H2,1H3
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n/an/a 8.18E+3n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50261618
PNG
(CHEMBL4061114)
Show SMILES COc1cc2CC3COC(=O)N3C(C)c2cc1OC1CCCC1
Show InChI InChI=1S/C18H23NO4/c1-11-15-9-17(23-14-5-3-4-6-14)16(21-2)8-12(15)7-13-10-22-18(20)19(11)13/h8-9,11,13-14H,3-7,10H2,1-2H3
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n/an/a 1.28E+4n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4D isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50261614
PNG
(CHEMBL4082992)
Show SMILES COc1cc2CC3COC(=O)N3Cc2cc1OC1CCCCC1
Show InChI InChI=1S/C18H23NO4/c1-21-16-8-12-7-14-11-22-18(20)19(14)10-13(12)9-17(16)23-15-5-3-2-4-6-15/h8-9,14-15H,2-7,10-11H2,1H3
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n/an/a 1.39E+4n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4D isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261621
PNG
(CHEMBL4088267)
Show SMILES CCCOc1cc2CN3C(COC3=O)Cc2cc1OC
Show InChI InChI=1S/C15H19NO4/c1-3-4-19-14-7-11-8-16-12(9-20-15(16)17)5-10(11)6-13(14)18-2/h6-7,12H,3-5,8-9H2,1-2H3
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n/an/a 2.24E+4n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50261617
PNG
(CHEMBL4072507)
Show SMILES CCCCCCC1N2C(COC2=O)Cc2cc(OC)c(OC3CCCC3)cc12
Show InChI InChI=1S/C23H33NO4/c1-3-4-5-6-11-20-19-14-22(28-18-9-7-8-10-18)21(26-2)13-16(19)12-17-15-27-23(25)24(17)20/h13-14,17-18,20H,3-12,15H2,1-2H3
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n/an/a 2.31E+4n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4D isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50261616
PNG
(CHEMBL4077155)
Show SMILES CCCCCOc1cc2CN3C(COC3=O)Cc2cc1OC
Show InChI InChI=1S/C17H23NO4/c1-3-4-5-6-21-16-9-13-10-18-14(11-22-17(18)19)7-12(13)8-15(16)20-2/h8-9,14H,3-7,10-11H2,1-2H3
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n/an/a 2.33E+4n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4D isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50261612
PNG
(CHEMBL4099426)
Show SMILES COc1cc2CC3COC(=O)N3C(C3CCCCC3)c2cc1OC1CCCC1
Show InChI InChI=1S/C23H31NO4/c1-26-20-12-16-11-17-14-27-23(25)24(17)22(15-7-3-2-4-8-15)19(16)13-21(20)28-18-9-5-6-10-18/h12-13,15,17-18,22H,2-11,14H2,1H3
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n/an/a 2.68E+4n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4D isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50261613
PNG
(CHEMBL4063909)
Show SMILES COc1cc2CC3COC(=O)N3C(c3ccccc3)c2cc1OC1CCCC1
Show InChI InChI=1S/C23H25NO4/c1-26-20-12-16-11-17-14-27-23(25)24(17)22(15-7-3-2-4-8-15)19(16)13-21(20)28-18-9-5-6-10-18/h2-4,7-8,12-13,17-18,22H,5-6,9-11,14H2,1H3
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n/an/a 3.17E+4n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4D isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261622
PNG
(CHEMBL4078521)
Show SMILES COc1cc2CC3COC(=O)N3Cc2cc1OC
Show InChI InChI=1S/C13H15NO4/c1-16-11-4-8-3-10-7-18-13(15)14(10)6-9(8)5-12(11)17-2/h4-5,10H,3,6-7H2,1-2H3
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n/an/a 5.21E+4n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50261632
PNG
(CHEMBL4067625)
Show SMILES COc1cc2CC3COC(=O)N3Cc2cc1O
Show InChI InChI=1S/C12H13NO4/c1-16-11-4-7-2-9-6-17-12(15)13(9)5-8(7)3-10(11)14/h3-4,9,14H,2,5-6H2,1H3
PDB

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n/an/a>1.00E+5n/an/an/an/an/an/a



State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, South China Agricultural University, Guangzhou 510642, China; College of Materials and Energy, South China Agri

Curated by ChEMBL


Assay Description
Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 mins

Bioorg Med Chem 25: 5709-5717 (2017)


Article DOI: 10.1016/j.bmc.2017.08.045
BindingDB Entry DOI: 10.7270/Q2PG1V62
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%