Affinity Data by PubMed id=29019677

PubMed code 29019677

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 2 (Homo sapiens (Human))	BDBM27497 (2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...) Show SMILES CN(C)CC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Queen's Center for Biomedical REsearch Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition against 4-hydroxyphenylpyruvate dioxygenase from pig liver; (observed value)				J Nat Prod 80: 2741-2750 (2017) Article DOI: 10.1021/acs.jnatprod.7b00515 BindingDB Entry DOI: 10.7270/Q2GH9MHQ
Queen's Center for Biomedical REsearch Curated by ChEMBL					More data for this Ligand-Target Pair
Phospholipase A2 (Apis mellifera)	BDBM50242184 (Scalaradial) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Queen's Center for Biomedical REsearch Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)				J Nat Prod 80: 2741-2750 (2017) Article DOI: 10.1021/acs.jnatprod.7b00515 BindingDB Entry DOI: 10.7270/Q2GH9MHQ
Queen's Center for Biomedical REsearch Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2 (Homo sapiens (Human))	BDBM50242184 (Scalaradial) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Queen's Center for Biomedical REsearch Curated by ChEMBL					Assay Description Inhibition of human FLAG-tagged TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced intracellular calcium flux after 30 to 60 mins ...				J Nat Prod 80: 2741-2750 (2017) Article DOI: 10.1021/acs.jnatprod.7b00515 BindingDB Entry DOI: 10.7270/Q2GH9MHQ
Queen's Center for Biomedical REsearch Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2 (Rattus norvegicus)	BDBM50242184 (Scalaradial) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Queen's Center for Biomedical REsearch Curated by ChEMBL					Assay Description Inhibition of TRPM2 in rat INS-1 cells assessed as reduction in ADPR-induced intracellular calcium flux measured after 60 mins by whole cell patch cl...				J Nat Prod 80: 2741-2750 (2017) Article DOI: 10.1021/acs.jnatprod.7b00515 BindingDB Entry DOI: 10.7270/Q2GH9MHQ
Queen's Center for Biomedical REsearch Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2 (Homo sapiens (Human))	BDBM27502 (3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoq...) Show SMILES O=C1NCCc2c(OCCCCN3CCCCC3)cccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Queen's Center for Biomedical REsearch Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition against 4-hydroxyphenylpyruvate dioxygenase from pig liver; (observed value)				J Nat Prod 80: 2741-2750 (2017) Article DOI: 10.1021/acs.jnatprod.7b00515 BindingDB Entry DOI: 10.7270/Q2GH9MHQ
Queen's Center for Biomedical REsearch Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 7 (Mus musculus)	BDBM50242184 (Scalaradial) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Queen's Center for Biomedical REsearch Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)				J Nat Prod 80: 2741-2750 (2017) Article DOI: 10.1021/acs.jnatprod.7b00515 BindingDB Entry DOI: 10.7270/Q2GH9MHQ
Queen's Center for Biomedical REsearch Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2 (Homo sapiens (Human))	BDBM50278349 (2-(Diphenylboryloxy)Ethanamine \| 2-Aminoethoxydiph...) Show SMILES NCCOB(c1ccccc1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Queen's Center for Biomedical REsearch Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)				J Nat Prod 80: 2741-2750 (2017) Article DOI: 10.1021/acs.jnatprod.7b00515 BindingDB Entry DOI: 10.7270/Q2GH9MHQ
Queen's Center for Biomedical REsearch Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 2 (Homo sapiens (Human))	BDBM50227083 (CHEMBL173443) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Queen's Center for Biomedical REsearch Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)				J Nat Prod 80: 2741-2750 (2017) Article DOI: 10.1021/acs.jnatprod.7b00515 BindingDB Entry DOI: 10.7270/Q2GH9MHQ
Queen's Center for Biomedical REsearch Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%