Affinity Data by PubMed id=29615345

PubMed code 29615345

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50271615 (CHEMBL4130213) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.13E+4	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
Suez Canal University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50271610 (CHEMBL418695) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.94E+3	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human N-terminal GAL4-DBD fused PPARgamma LBD expressed in reporter cells measured after 24 hrs by luciferase reporter...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
Suez Canal University Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50271612 (CHEMBL4127761) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.31E+3	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
Suez Canal University Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50271614 (CHEMBL4126802) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
Suez Canal University Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50271610 (CHEMBL418695) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
Suez Canal University Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50271613 (CHEMBL4127972) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
Suez Canal University Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50271616 (CHEMBL4127920) Show SMILES CCCCC\C=C\C\C=C\C\C=C\CCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
Suez Canal University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50271611 (CHEMBL4125720) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.51E+3	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human N-terminal GAL4-DBD fused PPARgamma LBD expressed in reporter cells measured after 24 hrs by luciferase reporter...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
Suez Canal University Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50271611 (CHEMBL4125720) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.06E+3	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
Suez Canal University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50030474 (Avandamet \| Avandaryl \| Avandia \| BRL-49653 \| CHEB...) Show SMILES CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human N-terminal GAL4-DBD fused PPARgamma LBD expressed in reporter cells measured after 24 hrs by luciferase reporter...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
Suez Canal University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50271612 (CHEMBL4127761) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of recombinant human N-terminal GAL4-DBD fused PPARgamma LBD expressed in reporter cells measured after 24 hrs by luciferase reporter...				Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR
Suez Canal University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%