Affinity Data by PubMed id=3031294

PubMed code 3031294

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24182 (4-amino-3-(4-chlorophenyl)butanoic acid \| Baclofen...) Show SMILES NCC(CC(O)=O)c1ccc(Cl)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021755 (4-Amino-3-(5-methoxy-benzofuran-2-yl)-butyric acid...) Show SMILES COc1ccc2oc(cc2c1)C(CN)CC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021756 (4-Amino-3-benzofuran-2-yl-butyric acid \| CHEMBL349...) Show SMILES NCC(CC(O)=O)c1cc2ccccc2o1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021758 (4-Amino-3-(2,3-dihydro-benzofuran-2-yl)-butyric ac...) Show SMILES NCC(CC(O)=O)C1Cc2ccccc2O1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007120 (4-Amino-3-(4-hydroxy-phenyl)-butyric acid \| CHEMBL...) Show SMILES NCC(CC(O)=O)c1ccc(O)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021759 (4-Amino-3-(5-methoxy-2,3-dihydro-benzofuran-2-yl)-...) Show SMILES COc1ccc2OC(Cc2c1)C(CN)CC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021757 (4-Amino-3-(4-benzyloxy-phenyl)-butyric acid; hydro...) Show SMILES NCC(CC(O)=O)c1ccc(OCc2ccccc2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021761 (4-Amino-3-[4-(4-fluoro-benzyloxy)-phenyl]-butyric ...) Show SMILES NCC(CC(O)=O)c1ccc(OCc2ccc(F)cc2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021763 (4-Amino-3-(3-methyl-2-oxo-2,3-dihydro-benzooxazol-...) Show SMILES Cn1c2ccc(cc2oc1=O)C(CN)CC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%