Affinity Data by PubMed id=30975505

PubMed code 30975505

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM430732 ((R)-(4-fluorophenyl)(8-methyl-3-(quinolin-2-yl)-5,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Antagonistic activity against NK3R (unknown origin) expressed in CHO cells assessed as inhibition of NKB-induced intracellular calcium flux by Calciu...				Bioorg Med Chem 27: 2019-2026 (2019) Article DOI: 10.1016/j.bmc.2019.03.059 BindingDB Entry DOI: 10.7270/Q26T0R36
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50524029 (CHEMBL4567857) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Antagonistic activity against NK3R (unknown origin) expressed in CHO cells assessed as inhibition of NKB-induced intracellular calcium flux by Calciu...				Bioorg Med Chem 27: 2019-2026 (2019) Article DOI: 10.1016/j.bmc.2019.03.059 BindingDB Entry DOI: 10.7270/Q26T0R36
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50524033 (CHEMBL4558106) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Antagonistic activity against NK3R (unknown origin) expressed in CHO cells assessed as inhibition of NKB-induced intracellular calcium flux by Calciu...				Bioorg Med Chem 27: 2019-2026 (2019) Article DOI: 10.1016/j.bmc.2019.03.059 BindingDB Entry DOI: 10.7270/Q26T0R36
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50524032 (CHEMBL4569878) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Antagonistic activity against NK3R (unknown origin) expressed in CHO cells assessed as inhibition of NKB-induced intracellular calcium flux by Calciu...				Bioorg Med Chem 27: 2019-2026 (2019) Article DOI: 10.1016/j.bmc.2019.03.059 BindingDB Entry DOI: 10.7270/Q26T0R36
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50524031 (CHEMBL4437427) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Antagonistic activity against NK3R (unknown origin) expressed in CHO cells assessed as inhibition of NKB-induced intracellular calcium flux by Calciu...				Bioorg Med Chem 27: 2019-2026 (2019) Article DOI: 10.1016/j.bmc.2019.03.059 BindingDB Entry DOI: 10.7270/Q26T0R36
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50524030 (CHEMBL4516772) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Antagonistic activity against NK3R (unknown origin) expressed in CHO cells assessed as inhibition of NKB-induced intracellular calcium flux by Calciu...				Bioorg Med Chem 27: 2019-2026 (2019) Article DOI: 10.1016/j.bmc.2019.03.059 BindingDB Entry DOI: 10.7270/Q26T0R36
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50524032 (CHEMBL4569878) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Antagonistic activity against NK3R (unknown origin) expressed in CHO cells assessed as inhibition of NKB-induced intracellular calcium flux under UV-...				Bioorg Med Chem 27: 2019-2026 (2019) Article DOI: 10.1016/j.bmc.2019.03.059 BindingDB Entry DOI: 10.7270/Q26T0R36
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%