Affinity Data by PubMed id=31005444

PubMed code 31005444

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50510071 (CHEMBL4541082) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Competitive displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintill...				Bioorg Med Chem Lett 29: 1476-1480 (2019) Article DOI: 10.1016/j.bmcl.2019.04.018 BindingDB Entry DOI: 10.7270/Q2C250RG
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50510072 (CHEMBL4435339) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Competitive displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintill...				Bioorg Med Chem Lett 29: 1476-1480 (2019) Article DOI: 10.1016/j.bmcl.2019.04.018 BindingDB Entry DOI: 10.7270/Q2C250RG
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416603 (CHEMBL1222883) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Competitive displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintill...				Bioorg Med Chem Lett 29: 1476-1480 (2019) Article DOI: 10.1016/j.bmcl.2019.04.018 BindingDB Entry DOI: 10.7270/Q2C250RG
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50510070 (CHEMBL2218191) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Competitive displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintill...				Bioorg Med Chem Lett 29: 1476-1480 (2019) Article DOI: 10.1016/j.bmcl.2019.04.018 BindingDB Entry DOI: 10.7270/Q2C250RG
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50510071 (CHEMBL4541082) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintillation counti...				Bioorg Med Chem Lett 29: 1476-1480 (2019) Article DOI: 10.1016/j.bmcl.2019.04.018 BindingDB Entry DOI: 10.7270/Q2C250RG
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50510072 (CHEMBL4435339) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintillation counti...				Bioorg Med Chem Lett 29: 1476-1480 (2019) Article DOI: 10.1016/j.bmcl.2019.04.018 BindingDB Entry DOI: 10.7270/Q2C250RG
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416603 (CHEMBL1222883) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintillation counti...				Bioorg Med Chem Lett 29: 1476-1480 (2019) Article DOI: 10.1016/j.bmcl.2019.04.018 BindingDB Entry DOI: 10.7270/Q2C250RG
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50510070 (CHEMBL2218191) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintillation counti...				Bioorg Med Chem Lett 29: 1476-1480 (2019) Article DOI: 10.1016/j.bmcl.2019.04.018 BindingDB Entry DOI: 10.7270/Q2C250RG
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%