Affinity Data by PubMed id=31413809

PubMed code 31413809

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50502619 (CHEMBL4561264) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.398	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...				ACS Med Chem Lett 10: 1222-1227 (2019) Article DOI: 10.1021/acsmedchemlett.9b00261 BindingDB Entry DOI: 10.7270/Q2WM1HPF
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50502622 (CHEMBL4579467) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...				ACS Med Chem Lett 10: 1222-1227 (2019) Article DOI: 10.1021/acsmedchemlett.9b00261 BindingDB Entry DOI: 10.7270/Q2WM1HPF
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50502621 (CHEMBL4513306) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...				ACS Med Chem Lett 10: 1222-1227 (2019) Article DOI: 10.1021/acsmedchemlett.9b00261 BindingDB Entry DOI: 10.7270/Q2WM1HPF
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50502616 (CHEMBL4564319) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human DPPI using H-Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...				ACS Med Chem Lett 10: 1222-1227 (2019) Article DOI: 10.1021/acsmedchemlett.9b00261 BindingDB Entry DOI: 10.7270/Q2WM1HPF
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50502617 (CHEMBL4570759) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...				ACS Med Chem Lett 10: 1222-1227 (2019) Article DOI: 10.1021/acsmedchemlett.9b00261 BindingDB Entry DOI: 10.7270/Q2WM1HPF
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50502620 (CHEMBL4451898) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...				ACS Med Chem Lett 10: 1222-1227 (2019) Article DOI: 10.1021/acsmedchemlett.9b00261 BindingDB Entry DOI: 10.7270/Q2WM1HPF
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50502623 (CHEMBL4538307) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human DPPI using H-Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...				ACS Med Chem Lett 10: 1222-1227 (2019) Article DOI: 10.1021/acsmedchemlett.9b00261 BindingDB Entry DOI: 10.7270/Q2WM1HPF
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50502618 (CHEMBL4461966) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...				ACS Med Chem Lett 10: 1222-1227 (2019) Article DOI: 10.1021/acsmedchemlett.9b00261 BindingDB Entry DOI: 10.7270/Q2WM1HPF
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%