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PubMed code 31494468

Compile data set for download or QSAR
Found 61 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515950
PNG
(CHEMBL4549866)
Show SMILES COc1cc(\C=C\C(=O)OCCCN(C)C[C@H](C)COC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C35H39NO7/c1-24(23-43-35(38)33-28-13-8-6-11-26(28)21-27-12-7-9-14-29(27)33)22-36(2)17-10-18-42-32(37)16-15-25-19-30(39-3)34(41-5)31(20-25)40-4/h6-9,11-16,19-21,24H,10,17-18,22-23H2,1-5H3/b16-15+/t24-/m0/s1
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n/an/an/an/a 910n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515948
PNG
(CHEMBL4436357)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C35H39NO7/c1-24(23-43-32(37)16-15-25-19-30(39-3)34(41-5)31(20-25)40-4)22-36(2)17-10-18-42-35(38)33-28-13-8-6-11-26(28)21-27-12-7-9-14-29(27)33/h6-9,11-16,19-21,24H,10,17-18,22-23H2,1-5H3/b16-15+/t24-/m0/s1
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n/an/an/an/a 2.30E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50515954
PNG
(CHEMBL4550006)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCCCN(C)C[C@@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C34H49NO10/c1-24(23-45-34(37)26-20-29(40-5)33(43-8)30(21-26)41-6)22-35(2)16-12-10-9-11-13-17-44-31(36)15-14-25-18-27(38-3)32(42-7)28(19-25)39-4/h14-15,18-21,24H,9-13,16-17,22-23H2,1-8H3/b15-14+/t24-/m1/s1
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n/an/an/an/a 3.50E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515964
PNG
(CHEMBL4590439)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C35H39NO7/c1-24(23-43-32(37)16-15-25-19-30(39-3)34(41-5)31(20-25)40-4)22-36(2)17-10-18-42-35(38)33-28-13-8-6-11-26(28)21-27-12-7-9-14-29(27)33/h6-9,11-16,19-21,24H,10,17-18,22-23H2,1-5H3/b16-15+/t24-/m1/s1
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n/an/an/an/a 950n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM81939
PNG
(CAS_52-53-9 | NSC_62969 | VERAPAMIL)
Show SMILES COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC
Show InChI InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3
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n/an/an/an/a 6.80E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515957
PNG
(CHEMBL4468999)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCN(C)C[C@@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C32H45NO10/c1-22(21-43-32(35)24-18-27(38-5)31(41-8)28(19-24)39-6)20-33(2)14-10-9-11-15-42-29(34)13-12-23-16-25(36-3)30(40-7)26(17-23)37-4/h12-13,16-19,22H,9-11,14-15,20-21H2,1-8H3/b13-12+/t22-/m1/s1
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n/an/an/an/a 4.10E+4n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515955
PNG
(CHEMBL4559743)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCCCCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C39H47NO7/c1-28(27-47-36(41)20-19-29-23-34(43-3)38(45-5)35(24-29)44-4)26-40(2)21-13-7-6-8-14-22-46-39(42)37-32-17-11-9-15-30(32)25-31-16-10-12-18-33(31)37/h9-12,15-20,23-25,28H,6-8,13-14,21-22,26-27H2,1-5H3/b20-19+/t28-/m1/s1
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n/an/an/an/a 6.40E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515957
PNG
(CHEMBL4468999)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCN(C)C[C@@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C32H45NO10/c1-22(21-43-32(35)24-18-27(38-5)31(41-8)28(19-24)39-6)20-33(2)14-10-9-11-15-42-29(34)13-12-23-16-25(36-3)30(40-7)26(17-23)37-4/h12-13,16-19,22H,9-11,14-15,20-21H2,1-8H3/b13-12+/t22-/m1/s1
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n/an/an/an/a 310n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50515946
PNG
(CHEMBL4583848)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCCCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C34H49NO10/c1-24(23-45-31(36)15-14-25-18-27(38-3)32(42-7)28(19-25)39-4)22-35(2)16-12-10-9-11-13-17-44-34(37)26-20-29(40-5)33(43-8)30(21-26)41-6/h14-15,18-21,24H,9-13,16-17,22-23H2,1-8H3/b15-14+/t24-/m1/s1
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n/an/an/an/a 3.70E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515946
PNG
(CHEMBL4583848)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCCCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C34H49NO10/c1-24(23-45-31(36)15-14-25-18-27(38-3)32(42-7)28(19-25)39-4)22-35(2)16-12-10-9-11-13-17-44-34(37)26-20-29(40-5)33(43-8)30(21-26)41-6/h14-15,18-21,24H,9-13,16-17,22-23H2,1-8H3/b15-14+/t24-/m1/s1
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n/an/an/an/a 820n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50515958
PNG
(CHEMBL4572151)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCCCN(C)C[C@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C34H49NO10/c1-24(23-45-34(37)26-20-29(40-5)33(43-8)30(21-26)41-6)22-35(2)16-12-10-9-11-13-17-44-31(36)15-14-25-18-27(38-3)32(42-7)28(19-25)39-4/h14-15,18-21,24H,9-13,16-17,22-23H2,1-8H3/b15-14+/t24-/m0/s1
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n/an/an/an/a 2.80E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515959
PNG
(CHEMBL4449424)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C30H41NO10/c1-20(19-41-27(32)11-10-21-14-23(34-3)28(38-7)24(15-21)35-4)18-31(2)12-9-13-40-30(33)22-16-25(36-5)29(39-8)26(17-22)37-6/h10-11,14-17,20H,9,12-13,18-19H2,1-8H3/b11-10+/t20-/m0/s1
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n/an/an/an/a 3.70E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515951
PNG
(CHEMBL4550859)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C37H43NO7/c1-26(25-45-34(39)18-17-27-21-32(41-3)36(43-5)33(22-27)42-4)24-38(2)19-11-6-12-20-44-37(40)35-30-15-9-7-13-28(30)23-29-14-8-10-16-31(29)35/h7-10,13-18,21-23,26H,6,11-12,19-20,24-25H2,1-5H3/b18-17+/t26-/m1/s1
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n/an/an/an/a 2.30E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515954
PNG
(CHEMBL4550006)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCCCN(C)C[C@@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C34H49NO10/c1-24(23-45-34(37)26-20-29(40-5)33(43-8)30(21-26)41-6)22-35(2)16-12-10-9-11-13-17-44-31(36)15-14-25-18-27(38-3)32(42-7)28(19-25)39-4/h14-15,18-21,24H,9-13,16-17,22-23H2,1-8H3/b15-14+/t24-/m1/s1
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n/an/an/an/a 4.30E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50515960
PNG
(CHEMBL4564520)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C32H45NO10/c1-22(21-43-29(34)13-12-23-16-25(36-3)30(40-7)26(17-23)37-4)20-33(2)14-10-9-11-15-42-32(35)24-18-27(38-5)31(41-8)28(19-24)39-6/h12-13,16-19,22H,9-11,14-15,20-21H2,1-8H3/b13-12+/t22-/m0/s1
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n/an/an/an/a 1.01E+4n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515963
PNG
(CHEMBL4465427)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCCCN(C)C[C@H](C)COC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C39H47NO7/c1-28(27-47-39(42)37-32-17-11-9-15-30(32)25-31-16-10-12-18-33(31)37)26-40(2)21-13-7-6-8-14-22-46-36(41)20-19-29-23-34(43-3)38(45-5)35(24-29)44-4/h9-12,15-20,23-25,28H,6-8,13-14,21-22,26-27H2,1-5H3/b20-19+/t28-/m0/s1
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n/an/an/an/a 7.20E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515947
PNG
(CHEMBL4469835)
Show SMILES COc1cc(\C=C\C(=O)OCCCN(C)C[C@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C30H41NO10/c1-20(19-41-30(33)22-16-25(36-5)29(39-8)26(17-22)37-6)18-31(2)12-9-13-40-27(32)11-10-21-14-23(34-3)28(38-7)24(15-21)35-4/h10-11,14-17,20H,9,12-13,18-19H2,1-8H3/b11-10+/t20-/m0/s1
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n/an/an/an/a 550n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515949
PNG
(CHEMBL4525382)
Show SMILES COc1cc(\C=C\C(=O)OCCCN(C)C[C@@H](C)COC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C35H39NO7/c1-24(23-43-35(38)33-28-13-8-6-11-26(28)21-27-12-7-9-14-29(27)33)22-36(2)17-10-18-42-32(37)16-15-25-19-30(39-3)34(41-5)31(20-25)40-4/h6-9,11-16,19-21,24H,10,17-18,22-23H2,1-5H3/b16-15+/t24-/m1/s1
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n/an/an/an/a 960n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515953
PNG
(CHEMBL4476816)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCCCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C34H49NO10/c1-24(23-45-31(36)15-14-25-18-27(38-3)32(42-7)28(19-25)39-4)22-35(2)16-12-10-9-11-13-17-44-34(37)26-20-29(40-5)33(43-8)30(21-26)41-6/h14-15,18-21,24H,9-13,16-17,22-23H2,1-8H3/b15-14+/t24-/m0/s1
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n/an/an/an/a 320n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515954
PNG
(CHEMBL4550006)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCCCN(C)C[C@@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C34H49NO10/c1-24(23-45-34(37)26-20-29(40-5)33(43-8)30(21-26)41-6)22-35(2)16-12-10-9-11-13-17-44-31(36)15-14-25-18-27(38-3)32(42-7)28(19-25)39-4/h14-15,18-21,24H,9-13,16-17,22-23H2,1-8H3/b15-14+/t24-/m1/s1
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n/an/an/an/a 650n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50515957
PNG
(CHEMBL4468999)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCN(C)C[C@@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C32H45NO10/c1-22(21-43-32(35)24-18-27(38-5)31(41-8)28(19-24)39-6)20-33(2)14-10-9-11-15-42-29(34)13-12-23-16-25(36-3)30(40-7)26(17-23)37-4/h12-13,16-19,22H,9-11,14-15,20-21H2,1-8H3/b13-12+/t22-/m1/s1
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n/an/an/an/a 5.80E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50515943
PNG
(CHEMBL4457942)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCN(C)C[C@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C32H45NO10/c1-22(21-43-32(35)24-18-27(38-5)31(41-8)28(19-24)39-6)20-33(2)14-10-9-11-15-42-29(34)13-12-23-16-25(36-3)30(40-7)26(17-23)37-4/h12-13,16-19,22H,9-11,14-15,20-21H2,1-8H3/b13-12+/t22-/m0/s1
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n/an/an/an/a 4.40E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515942
PNG
(CHEMBL4452443)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C30H41NO10/c1-20(19-41-27(32)11-10-21-14-23(34-3)28(38-7)24(15-21)35-4)18-31(2)12-9-13-40-30(33)22-16-25(36-5)29(39-8)26(17-22)37-6/h10-11,14-17,20H,9,12-13,18-19H2,1-8H3/b11-10+/t20-/m1/s1
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n/an/an/an/a 710n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515945
PNG
(CHEMBL4461339)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCCCCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C39H47NO7/c1-28(27-47-36(41)20-19-29-23-34(43-3)38(45-5)35(24-29)44-4)26-40(2)21-13-7-6-8-14-22-46-39(42)37-32-17-11-9-15-30(32)25-31-16-10-12-18-33(31)37/h9-12,15-20,23-25,28H,6-8,13-14,21-22,26-27H2,1-5H3/b20-19+/t28-/m0/s1
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n/an/an/an/a 930n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515947
PNG
(CHEMBL4469835)
Show SMILES COc1cc(\C=C\C(=O)OCCCN(C)C[C@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C30H41NO10/c1-20(19-41-30(33)22-16-25(36-5)29(39-8)26(17-22)37-6)18-31(2)12-9-13-40-27(32)11-10-21-14-23(34-3)28(38-7)24(15-21)35-4/h10-11,14-17,20H,9,12-13,18-19H2,1-8H3/b11-10+/t20-/m0/s1
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n/an/an/an/a 6.40E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515950
PNG
(CHEMBL4549866)
Show SMILES COc1cc(\C=C\C(=O)OCCCN(C)C[C@H](C)COC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C35H39NO7/c1-24(23-43-35(38)33-28-13-8-6-11-26(28)21-27-12-7-9-14-29(27)33)22-36(2)17-10-18-42-32(37)16-15-25-19-30(39-3)34(41-5)31(20-25)40-4/h6-9,11-16,19-21,24H,10,17-18,22-23H2,1-5H3/b16-15+/t24-/m0/s1
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n/an/an/an/a 1.10E+4n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515956
PNG
(CHEMBL4589005)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C32H45NO10/c1-22(21-43-29(34)13-12-23-16-25(36-3)30(40-7)26(17-23)37-4)20-33(2)14-10-9-11-15-42-32(35)24-18-27(38-5)31(41-8)28(19-24)39-6/h12-13,16-19,22H,9-11,14-15,20-21H2,1-8H3/b13-12+/t22-/m1/s1
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n/an/an/an/a 1.00E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515962
PNG
(CHEMBL4548976)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCN(C)C[C@H](C)COC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C37H43NO7/c1-26(25-45-37(40)35-30-15-9-7-13-28(30)23-29-14-8-10-16-31(29)35)24-38(2)19-11-6-12-20-44-34(39)18-17-27-21-32(41-3)36(43-5)33(22-27)42-4/h7-10,13-18,21-23,26H,6,11-12,19-20,24-25H2,1-5H3/b18-17+/t26-/m0/s1
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n/an/an/an/a 4.60E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515965
PNG
(CHEMBL4439920)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCN(C)C[C@@H](C)COC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C37H43NO7/c1-26(25-45-37(40)35-30-15-9-7-13-28(30)23-29-14-8-10-16-31(29)35)24-38(2)19-11-6-12-20-44-34(39)18-17-27-21-32(41-3)36(43-5)33(22-27)42-4/h7-10,13-18,21-23,26H,6,11-12,19-20,24-25H2,1-5H3/b18-17+/t26-/m1/s1
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n/an/an/an/a 810n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50515959
PNG
(CHEMBL4449424)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C30H41NO10/c1-20(19-41-27(32)11-10-21-14-23(34-3)28(38-7)24(15-21)35-4)18-31(2)12-9-13-40-30(33)22-16-25(36-5)29(39-8)26(17-22)37-6/h10-11,14-17,20H,9,12-13,18-19H2,1-8H3/b11-10+/t20-/m0/s1
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n/an/an/an/a 1.27E+4n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515943
PNG
(CHEMBL4457942)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCN(C)C[C@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C32H45NO10/c1-22(21-43-32(35)24-18-27(38-5)31(41-8)28(19-24)39-6)20-33(2)14-10-9-11-15-42-29(34)13-12-23-16-25(36-3)30(40-7)26(17-23)37-4/h12-13,16-19,22H,9-11,14-15,20-21H2,1-8H3/b13-12+/t22-/m0/s1
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n/an/an/an/a 110n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515943
PNG
(CHEMBL4457942)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCN(C)C[C@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C32H45NO10/c1-22(21-43-32(35)24-18-27(38-5)31(41-8)28(19-24)39-6)20-33(2)14-10-9-11-15-42-29(34)13-12-23-16-25(36-3)30(40-7)26(17-23)37-4/h12-13,16-19,22H,9-11,14-15,20-21H2,1-8H3/b13-12+/t22-/m0/s1
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n/an/an/an/a 8.10E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515948
PNG
(CHEMBL4436357)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C35H39NO7/c1-24(23-43-32(37)16-15-25-19-30(39-3)34(41-5)31(20-25)40-4)22-36(2)17-10-18-42-35(38)33-28-13-8-6-11-26(28)21-27-12-7-9-14-29(27)33/h6-9,11-16,19-21,24H,10,17-18,22-23H2,1-5H3/b16-15+/t24-/m0/s1
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n/an/an/an/a 910n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515946
PNG
(CHEMBL4583848)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCCCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C34H49NO10/c1-24(23-45-31(36)15-14-25-18-27(38-3)32(42-7)28(19-25)39-4)22-35(2)16-12-10-9-11-13-17-44-34(37)26-20-29(40-5)33(43-8)30(21-26)41-6/h14-15,18-21,24H,9-13,16-17,22-23H2,1-8H3/b15-14+/t24-/m1/s1
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n/an/an/an/a 4.70E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515958
PNG
(CHEMBL4572151)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCCCN(C)C[C@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C34H49NO10/c1-24(23-45-34(37)26-20-29(40-5)33(43-8)30(21-26)41-6)22-35(2)16-12-10-9-11-13-17-44-31(36)15-14-25-18-27(38-3)32(42-7)28(19-25)39-4/h14-15,18-21,24H,9-13,16-17,22-23H2,1-8H3/b15-14+/t24-/m0/s1
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n/an/an/an/a 2.50E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515961
PNG
(CHEMBL4513635)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCCCN(C)C[C@@H](C)COC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C39H47NO7/c1-28(27-47-39(42)37-32-17-11-9-15-30(32)25-31-16-10-12-18-33(31)37)26-40(2)21-13-7-6-8-14-22-46-36(41)20-19-29-23-34(43-3)38(45-5)35(24-29)44-4/h9-12,15-20,23-25,28H,6-8,13-14,21-22,26-27H2,1-5H3/b20-19+/t28-/m1/s1
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n/an/an/an/a 6.20E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515965
PNG
(CHEMBL4439920)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCN(C)C[C@@H](C)COC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C37H43NO7/c1-26(25-45-37(40)35-30-15-9-7-13-28(30)23-29-14-8-10-16-31(29)35)24-38(2)19-11-6-12-20-44-34(39)18-17-27-21-32(41-3)36(43-5)33(22-27)42-4/h7-10,13-18,21-23,26H,6,11-12,19-20,24-25H2,1-5H3/b18-17+/t26-/m1/s1
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n/an/an/an/a 4.60E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50515942
PNG
(CHEMBL4452443)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C30H41NO10/c1-20(19-41-27(32)11-10-21-14-23(34-3)28(38-7)24(15-21)35-4)18-31(2)12-9-13-40-30(33)22-16-25(36-5)29(39-8)26(17-22)37-6/h10-11,14-17,20H,9,12-13,18-19H2,1-8H3/b11-10+/t20-/m1/s1
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n/an/an/an/a 5.60E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515959
PNG
(CHEMBL4449424)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C30H41NO10/c1-20(19-41-27(32)11-10-21-14-23(34-3)28(38-7)24(15-21)35-4)18-31(2)12-9-13-40-30(33)22-16-25(36-5)29(39-8)26(17-22)37-6/h10-11,14-17,20H,9,12-13,18-19H2,1-8H3/b11-10+/t20-/m0/s1
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n/an/an/an/a 1.38E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515944
PNG
(CHEMBL4474755)
Show SMILES COc1cc(\C=C\C(=O)OCCCN(C)C[C@@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C30H41NO10/c1-20(19-41-30(33)22-16-25(36-5)29(39-8)26(17-22)37-6)18-31(2)12-9-13-40-27(32)11-10-21-14-23(34-3)28(38-7)24(15-21)35-4/h10-11,14-17,20H,9,12-13,18-19H2,1-8H3/b11-10+/t20-/m1/s1
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n/an/an/an/a 9.50E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515944
PNG
(CHEMBL4474755)
Show SMILES COc1cc(\C=C\C(=O)OCCCN(C)C[C@@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C30H41NO10/c1-20(19-41-30(33)22-16-25(36-5)29(39-8)26(17-22)37-6)18-31(2)12-9-13-40-27(32)11-10-21-14-23(34-3)28(38-7)24(15-21)35-4/h10-11,14-17,20H,9,12-13,18-19H2,1-8H3/b11-10+/t20-/m1/s1
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n/an/an/an/a 73n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515952
PNG
(CHEMBL4473662)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C37H43NO7/c1-26(25-45-34(39)18-17-27-21-32(41-3)36(43-5)33(22-27)42-4)24-38(2)19-11-6-12-20-44-37(40)35-30-15-9-7-13-28(30)23-29-14-8-10-16-31(29)35/h7-10,13-18,21-23,26H,6,11-12,19-20,24-25H2,1-5H3/b18-17+/t26-/m0/s1
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n/an/an/an/a 690n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50515956
PNG
(CHEMBL4589005)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C32H45NO10/c1-22(21-43-29(34)13-12-23-16-25(36-3)30(40-7)26(17-23)37-4)20-33(2)14-10-9-11-15-42-32(35)24-18-27(38-5)31(41-8)28(19-24)39-6/h12-13,16-19,22H,9-11,14-15,20-21H2,1-8H3/b13-12+/t22-/m1/s1
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n/an/an/an/a 3.90E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515960
PNG
(CHEMBL4564520)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C32H45NO10/c1-22(21-43-29(34)13-12-23-16-25(36-3)30(40-7)26(17-23)37-4)20-33(2)14-10-9-11-15-42-32(35)24-18-27(38-5)31(41-8)28(19-24)39-6/h12-13,16-19,22H,9-11,14-15,20-21H2,1-8H3/b13-12+/t22-/m0/s1
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n/an/an/an/a 4.20E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515961
PNG
(CHEMBL4513635)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCCCN(C)C[C@@H](C)COC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C39H47NO7/c1-28(27-47-39(42)37-32-17-11-9-15-30(32)25-31-16-10-12-18-33(31)37)26-40(2)21-13-7-6-8-14-22-46-36(41)20-19-29-23-34(43-3)38(45-5)35(24-29)44-4/h9-12,15-20,23-25,28H,6-8,13-14,21-22,26-27H2,1-5H3/b20-19+/t28-/m1/s1
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n/an/an/an/a 990n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515953
PNG
(CHEMBL4476816)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCCCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C34H49NO10/c1-24(23-45-31(36)15-14-25-18-27(38-3)32(42-7)28(19-25)39-4)22-35(2)16-12-10-9-11-13-17-44-34(37)26-20-29(40-5)33(43-8)30(21-26)41-6/h14-15,18-21,24H,9-13,16-17,22-23H2,1-8H3/b15-14+/t24-/m0/s1
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n/an/an/an/a 2.30E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515945
PNG
(CHEMBL4461339)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCCCCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C39H47NO7/c1-28(27-47-36(41)20-19-29-23-34(43-3)38(45-5)35(24-29)44-4)26-40(2)21-13-7-6-8-14-22-46-39(42)37-32-17-11-9-15-30(32)25-31-16-10-12-18-33(31)37/h9-12,15-20,23-25,28H,6-8,13-14,21-22,26-27H2,1-5H3/b20-19+/t28-/m0/s1
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n/an/an/an/a 5.60E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM81939
PNG
(CAS_52-53-9 | NSC_62969 | VERAPAMIL)
Show SMILES COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC
Show InChI InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3
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n/an/an/an/a 500n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50515944
PNG
(CHEMBL4474755)
Show SMILES COc1cc(\C=C\C(=O)OCCCN(C)C[C@@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C30H41NO10/c1-20(19-41-30(33)22-16-25(36-5)29(39-8)26(17-22)37-6)18-31(2)12-9-13-40-27(32)11-10-21-14-23(34-3)28(38-7)24(15-21)35-4/h10-11,14-17,20H,9,12-13,18-19H2,1-8H3/b11-10+/t20-/m1/s1
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n/an/an/an/a 7.30E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM81939
PNG
(CAS_52-53-9 | NSC_62969 | VERAPAMIL)
Show SMILES COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC
Show InChI InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3
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n/an/an/an/a 900n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515962
PNG
(CHEMBL4548976)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCN(C)C[C@H](C)COC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C37H43NO7/c1-26(25-45-37(40)35-30-15-9-7-13-28(30)23-29-14-8-10-16-31(29)35)24-38(2)19-11-6-12-20-44-34(39)18-17-27-21-32(41-3)36(43-5)33(22-27)42-4/h7-10,13-18,21-23,26H,6,11-12,19-20,24-25H2,1-5H3/b18-17+/t26-/m0/s1
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n/an/an/an/a 760n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515960
PNG
(CHEMBL4564520)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C32H45NO10/c1-22(21-43-29(34)13-12-23-16-25(36-3)30(40-7)26(17-23)37-4)20-33(2)14-10-9-11-15-42-32(35)24-18-27(38-5)31(41-8)28(19-24)39-6/h12-13,16-19,22H,9-11,14-15,20-21H2,1-8H3/b13-12+/t22-/m0/s1
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n/an/an/an/a 1.10E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515958
PNG
(CHEMBL4572151)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCCCN(C)C[C@H](C)COC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C34H49NO10/c1-24(23-45-34(37)26-20-29(40-5)33(43-8)30(21-26)41-6)22-35(2)16-12-10-9-11-13-17-44-31(36)15-14-25-18-27(38-3)32(42-7)28(19-25)39-4/h14-15,18-21,24H,9-13,16-17,22-23H2,1-8H3/b15-14+/t24-/m0/s1
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n/an/an/an/a 550n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515964
PNG
(CHEMBL4590439)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C35H39NO7/c1-24(23-43-32(37)16-15-25-19-30(39-3)34(41-5)31(20-25)40-4)22-36(2)17-10-18-42-35(38)33-28-13-8-6-11-26(28)21-27-12-7-9-14-29(27)33/h6-9,11-16,19-21,24H,10,17-18,22-23H2,1-5H3/b16-15+/t24-/m1/s1
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n/an/an/an/a 5.90E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515951
PNG
(CHEMBL4550859)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C37H43NO7/c1-26(25-45-34(39)18-17-27-21-32(41-3)36(43-5)33(22-27)42-4)24-38(2)19-11-6-12-20-44-37(40)35-30-15-9-7-13-28(30)23-29-14-8-10-16-31(29)35/h7-10,13-18,21-23,26H,6,11-12,19-20,24-25H2,1-5H3/b18-17+/t26-/m1/s1
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n/an/an/an/a 720n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515955
PNG
(CHEMBL4559743)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCCCCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C39H47NO7/c1-28(27-47-36(41)20-19-29-23-34(43-3)38(45-5)35(24-29)44-4)26-40(2)21-13-7-6-8-14-22-46-39(42)37-32-17-11-9-15-30(32)25-31-16-10-12-18-33(31)37/h9-12,15-20,23-25,28H,6-8,13-14,21-22,26-27H2,1-5H3/b20-19+/t28-/m1/s1
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n/an/an/an/a 1.40E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515949
PNG
(CHEMBL4525382)
Show SMILES COc1cc(\C=C\C(=O)OCCCN(C)C[C@@H](C)COC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C35H39NO7/c1-24(23-43-35(38)33-28-13-8-6-11-26(28)21-27-12-7-9-14-29(27)33)22-36(2)17-10-18-42-32(37)16-15-25-19-30(39-3)34(41-5)31(20-25)40-4/h6-9,11-16,19-21,24H,10,17-18,22-23H2,1-5H3/b16-15+/t24-/m1/s1
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n/an/an/an/a 6.80E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515952
PNG
(CHEMBL4473662)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C37H43NO7/c1-26(25-45-34(39)18-17-27-21-32(41-3)36(43-5)33(22-27)42-4)24-38(2)19-11-6-12-20-44-37(40)35-30-15-9-7-13-28(30)23-29-14-8-10-16-31(29)35/h7-10,13-18,21-23,26H,6,11-12,19-20,24-25H2,1-5H3/b18-17+/t26-/m0/s1
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n/an/an/an/a 4.70E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50515963
PNG
(CHEMBL4465427)
Show SMILES COc1cc(\C=C\C(=O)OCCCCCCCN(C)C[C@H](C)COC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC |r|
Show InChI InChI=1S/C39H47NO7/c1-28(27-47-39(42)37-32-17-11-9-15-30(32)25-31-16-10-12-18-33(31)37)26-40(2)21-13-7-6-8-14-22-46-36(41)20-19-29-23-34(43-3)38(45-5)35(24-29)44-4/h9-12,15-20,23-25,28H,6-8,13-14,21-22,26-27H2,1-5H3/b20-19+/t28-/m0/s1
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n/an/an/an/a 1.04E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2


(Homo sapiens (Human))		BDBM50515942
PNG
(CHEMBL4452443)
Show SMILES COc1cc(\C=C\C(=O)OC[C@H](C)CN(C)CCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C30H41NO10/c1-20(19-41-27(32)11-10-21-14-23(34-3)28(38-7)24(15-21)35-4)18-31(2)12-9-13-40-30(33)22-16-25(36-5)29(39-8)26(17-22)37-6/h10-11,14-17,20H,9,12-13,18-19H2,1-8H3/b11-10+/t20-/m1/s1
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n/an/an/an/a 3.35E+4n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50515953
PNG
(CHEMBL4476816)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@H](C)CN(C)CCCCCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC |r|
Show InChI InChI=1S/C34H49NO10/c1-24(23-45-31(36)15-14-25-18-27(38-3)32(42-7)28(19-25)39-4)22-35(2)16-12-10-9-11-13-17-44-34(37)26-20-29(40-5)33(43-8)30(21-26)41-6/h14-15,18-21,24H,9-13,16-17,22-23H2,1-8H3/b15-14+/t24-/m0/s1
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n/an/an/an/a 1.90E+3n/an/an/an/a



University of Florence

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111655
BindingDB Entry DOI: 10.7270/Q2ZW1Q9C
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%